HEADER SIGNALING PROTEIN 15-JUL-15 5A8E TITLE THERMOSTABILISED BETA1-ADRENOCEPTOR WITH RATIONALLY DESIGNED INVERSE TITLE 2 AGONIST 7-METHYLCYANOPINDOLOL BOUND COMPND MOL_ID: 1; COMPND 2 MOLECULE: BETA1 ADRENERGIC RECEPTOR; COMPND 3 CHAIN: A; COMPND 4 ENGINEERED: YES; COMPND 5 MUTATION: YES; COMPND 6 OTHER_DETAILS: RESIDUES 3-32 AT THE N-TERMINUS AND RESIDUES 244-271 COMPND 7 OF THE THIRD INTRACELLULAR LOOP WERE DELETED FROM THE CONSTRUCT. THE COMPND 8 CONSTRUCT WAS TRUNCATED AFTER RESIDUE 367 AND A HEXAHIS TAG ADDED. SOURCE MOL_ID: 1; SOURCE 2 ORGANISM_SCIENTIFIC: MELEAGRIS GALLOPAVO; SOURCE 3 ORGANISM_COMMON: TURKEY; SOURCE 4 ORGANISM_TAXID: 9103; SOURCE 5 CELL: ERYTHROCYTE; SOURCE 6 EXPRESSION_SYSTEM: TRICHOPLUSIA NI; SOURCE 7 EXPRESSION_SYSTEM_COMMON: CABBAGE LOOPER; SOURCE 8 EXPRESSION_SYSTEM_TAXID: 7111; SOURCE 9 EXPRESSION_SYSTEM_CELL_LINE: HIGH FIVE; SOURCE 10 EXPRESSION_SYSTEM_VECTOR_TYPE: BACULOVIRUS; SOURCE 11 EXPRESSION_SYSTEM_PLASMID: PBACPAK8 KEYWDS SIGNALING PROTEIN, INVERSE AGONIST EXPDTA X-RAY DIFFRACTION AUTHOR T.SATO,J.G.BAKER,T.WARNE,G.A.BROWN,M.CONGREVE,A.G.W.LESLIE,C.G.TATE REVDAT 4 03-APR-19 5A8E 1 SOURCE REVDAT 3 06-MAR-19 5A8E 1 REMARK REVDAT 2 11-NOV-15 5A8E 1 JRNL REVDAT 1 30-SEP-15 5A8E 0 JRNL AUTH T.SATO,J.BAKER,T.WARNE,G.BROWN,A.LESLIE,M.CONGREVE,C.TATE JRNL TITL PHARMACOLOGICAL ANALYSIS AND STRUCTURE DETERMINATION OF JRNL TITL 2 7-METHYLCYANOPINDOLOL-BOUND BETA1-ADRENERGIC RECEPTOR. JRNL REF MOL.PHARMACOL. V. 88 1024 2015 JRNL REFN ISSN 0026-895X JRNL PMID 26385885 JRNL DOI 10.1124/MOL.115.101030 REMARK 2 REMARK 2 RESOLUTION. 2.40 ANGSTROMS. REMARK 3 REMARK 3 REFINEMENT. REMARK 3 PROGRAM : REFMAC 5.8.0107 REMARK 3 AUTHORS : MURSHUDOV,SKUBAK,LEBEDEV,PANNU,STEINER, REMARK 3 : NICHOLLS,WINN,LONG,VAGIN REMARK 3 REMARK 3 REFINEMENT TARGET : MAXIMUM LIKELIHOOD REMARK 3 REMARK 3 DATA USED IN REFINEMENT. REMARK 3 RESOLUTION RANGE HIGH (ANGSTROMS) : 2.40 REMARK 3 RESOLUTION RANGE LOW (ANGSTROMS) : 37.79 REMARK 3 DATA CUTOFF (SIGMA(F)) : NULL REMARK 3 COMPLETENESS FOR RANGE (%) : 98.0 REMARK 3 NUMBER OF REFLECTIONS : 11942 REMARK 3 REMARK 3 FIT TO DATA USED IN REFINEMENT. REMARK 3 CROSS-VALIDATION METHOD : THROUGHOUT REMARK 3 FREE R VALUE TEST SET SELECTION : RANDOM REMARK 3 R VALUE (WORKING + TEST SET) : 0.218 REMARK 3 R VALUE (WORKING SET) : 0.217 REMARK 3 FREE R VALUE : 0.248 REMARK 3 FREE R VALUE TEST SET SIZE (%) : 4.800 REMARK 3 FREE R VALUE TEST SET COUNT : 608 REMARK 3 REMARK 3 FIT IN THE HIGHEST RESOLUTION BIN. REMARK 3 TOTAL NUMBER OF BINS USED : 20 REMARK 3 BIN RESOLUTION RANGE HIGH (A) : 2.40 REMARK 3 BIN RESOLUTION RANGE LOW (A) : 2.46 REMARK 3 REFLECTION IN BIN (WORKING SET) : 847 REMARK 3 BIN COMPLETENESS (WORKING+TEST) (%) : 98.04 REMARK 3 BIN R VALUE (WORKING SET) : 0.2940 REMARK 3 BIN FREE R VALUE SET COUNT : 54 REMARK 3 BIN FREE R VALUE : 0.2850 REMARK 3 REMARK 3 NUMBER OF NON-HYDROGEN ATOMS USED IN REFINEMENT. REMARK 3 PROTEIN ATOMS : 2270 REMARK 3 NUCLEIC ACID ATOMS : 0 REMARK 3 HETEROGEN ATOMS : 137 REMARK 3 SOLVENT ATOMS : 26 REMARK 3 REMARK 3 B VALUES. REMARK 3 FROM WILSON PLOT (A**2) : NULL REMARK 3 MEAN B VALUE (OVERALL, A**2) : 39.35 REMARK 3 OVERALL ANISOTROPIC B VALUE. REMARK 3 B11 (A**2) : -0.03000 REMARK 3 B22 (A**2) : 0.09000 REMARK 3 B33 (A**2) : -0.06000 REMARK 3 B12 (A**2) : 0.00000 REMARK 3 B13 (A**2) : 0.00000 REMARK 3 B23 (A**2) : 0.00000 REMARK 3 REMARK 3 ESTIMATED OVERALL COORDINATE ERROR. REMARK 3 ESU BASED ON R VALUE (A): 0.561 REMARK 3 ESU BASED ON FREE R VALUE (A): 0.275 REMARK 3 ESU BASED ON MAXIMUM LIKELIHOOD (A): 0.223 REMARK 3 ESU FOR B VALUES BASED ON MAXIMUM LIKELIHOOD (A**2): 9.816 REMARK 3 REMARK 3 CORRELATION COEFFICIENTS. REMARK 3 CORRELATION COEFFICIENT FO-FC : 0.922 REMARK 3 CORRELATION COEFFICIENT FO-FC FREE : 0.905 REMARK 3 REMARK 3 RMS DEVIATIONS FROM IDEAL VALUES COUNT RMS WEIGHT REMARK 3 BOND LENGTHS REFINED ATOMS (A): 2461 ; 0.008 ; 0.020 REMARK 3 BOND LENGTHS OTHERS (A): 2510 ; 0.002 ; 0.020 REMARK 3 BOND ANGLES REFINED ATOMS (DEGREES): 3323 ; 1.290 ; 1.996 REMARK 3 BOND ANGLES OTHERS (DEGREES): 5740 ; 0.921 ; 3.000 REMARK 3 TORSION ANGLES, PERIOD 1 (DEGREES): 285 ; 4.987 ; 5.000 REMARK 3 TORSION ANGLES, PERIOD 2 (DEGREES): 86 ;36.951 ;21.860 REMARK 3 TORSION ANGLES, PERIOD 3 (DEGREES): 396 ;13.654 ;15.000 REMARK 3 TORSION ANGLES, PERIOD 4 (DEGREES): 17 ;15.620 ;15.000 REMARK 3 CHIRAL-CENTER RESTRAINTS (A**3): 387 ; 0.064 ; 0.200 REMARK 3 GENERAL PLANES REFINED ATOMS (A): 2600 ; 0.005 ; 0.020 REMARK 3 GENERAL PLANES OTHERS (A): 577 ; 0.001 ; 0.020 REMARK 3 NON-BONDED CONTACTS REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 NON-BONDED CONTACTS OTHERS (A): NULL ; NULL ; NULL REMARK 3 NON-BONDED TORSION REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 NON-BONDED TORSION OTHERS (A): NULL ; NULL ; NULL REMARK 3 H-BOND (X...Y) REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 H-BOND (X...Y) OTHERS (A): NULL ; NULL ; NULL REMARK 3 POTENTIAL METAL-ION REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 POTENTIAL METAL-ION OTHERS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY VDW REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY VDW OTHERS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY H-BOND REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY H-BOND OTHERS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY METAL-ION REFINED ATOMS (A): NULL ; NULL ; NULL REMARK 3 SYMMETRY METAL-ION OTHERS (A): NULL ; NULL ; NULL REMARK 3 REMARK 3 ISOTROPIC THERMAL FACTOR RESTRAINTS. COUNT RMS WEIGHT REMARK 3 MAIN-CHAIN BOND REFINED ATOMS (A**2): 1140 ; 1.370 ; 3.712 REMARK 3 MAIN-CHAIN BOND OTHER ATOMS (A**2): 1139 ; 1.370 ; 3.710 REMARK 3 MAIN-CHAIN ANGLE REFINED ATOMS (A**2): 1422 ; 2.378 ; 5.555 REMARK 3 MAIN-CHAIN ANGLE OTHER ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 SIDE-CHAIN BOND REFINED ATOMS (A**2): 1318 ; 1.555 ; 4.106 REMARK 3 SIDE-CHAIN BOND OTHER ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 SIDE-CHAIN ANGLE REFINED ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 SIDE-CHAIN ANGLE OTHER ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 LONG RANGE B REFINED ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 LONG RANGE B OTHER ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 REMARK 3 ANISOTROPIC THERMAL FACTOR RESTRAINTS. COUNT RMS WEIGHT REMARK 3 RIGID-BOND RESTRAINTS (A**2): NULL ; NULL ; NULL REMARK 3 SPHERICITY; FREE ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 SPHERICITY; BONDED ATOMS (A**2): NULL ; NULL ; NULL REMARK 3 REMARK 3 NCS RESTRAINTS STATISTICS REMARK 3 NUMBER OF DIFFERENT NCS GROUPS : NULL REMARK 3 REMARK 3 TLS DETAILS REMARK 3 NUMBER OF TLS GROUPS : NULL REMARK 3 REMARK 3 BULK SOLVENT MODELLING. REMARK 3 METHOD USED : MASK REMARK 3 PARAMETERS FOR MASK CALCULATION REMARK 3 VDW PROBE RADIUS : 1.20 REMARK 3 ION PROBE RADIUS : 0.80 REMARK 3 SHRINKAGE RADIUS : 0.80 REMARK 3 REMARK 3 OTHER REFINEMENT REMARKS: HYDROGENS HAVE BEEN ADDED IN THE RIDING REMARK 3 POSITIONS. U VALUES REFINED INDIVIDUALLY REMARK 4 REMARK 4 5A8E COMPLIES WITH FORMAT V. 3.30, 13-JUL-11 REMARK 100 REMARK 100 THIS ENTRY HAS BEEN PROCESSED BY PDBE ON 15-JUL-15. REMARK 100 THE DEPOSITION ID IS D_1290063698. REMARK 200 REMARK 200 EXPERIMENTAL DETAILS REMARK 200 EXPERIMENT TYPE : X-RAY DIFFRACTION REMARK 200 DATE OF DATA COLLECTION : NULL; NULL REMARK 200 TEMPERATURE (KELVIN) : 100; 100 REMARK 200 PH : 7 REMARK 200 NUMBER OF CRYSTALS USED : 4 REMARK 200 REMARK 200 SYNCHROTRON (Y/N) : Y; Y REMARK 200 RADIATION SOURCE : ESRF; DIAMOND REMARK 200 BEAMLINE : ID29; I24 REMARK 200 X-RAY GENERATOR MODEL : NULL; NULL REMARK 200 MONOCHROMATIC OR LAUE (M/L) : M; M REMARK 200 WAVELENGTH OR RANGE (A) : 0.8726; 0.969 REMARK 200 MONOCHROMATOR : NULL; NULL REMARK 200 OPTICS : NULL; NULL REMARK 200 REMARK 200 DETECTOR TYPE : PIXEL; CCD REMARK 200 DETECTOR MANUFACTURER : PILATUS; ADSC CCD REMARK 200 INTENSITY-INTEGRATION SOFTWARE : MOSFLM REMARK 200 DATA SCALING SOFTWARE : AIMLESS REMARK 200 REMARK 200 NUMBER OF UNIQUE REFLECTIONS : 12526 REMARK 200 RESOLUTION RANGE HIGH (A) : 2.400 REMARK 200 RESOLUTION RANGE LOW (A) : 37.800 REMARK 200 REJECTION CRITERIA (SIGMA(I)) : 2.000 REMARK 200 REMARK 200 OVERALL. REMARK 200 COMPLETENESS FOR RANGE (%) : 98.4 REMARK 200 DATA REDUNDANCY : 4.800 REMARK 200 R MERGE (I) : 0.16000 REMARK 200 R SYM (I) : NULL REMARK 200 <I/SIGMA(I)> FOR THE DATA SET : 8.2000 REMARK 200 REMARK 200 IN THE HIGHEST RESOLUTION SHELL. REMARK 200 HIGHEST RESOLUTION SHELL, RANGE HIGH (A) : 2.40 REMARK 200 HIGHEST RESOLUTION SHELL, RANGE LOW (A) : 2.53 REMARK 200 COMPLETENESS FOR SHELL (%) : 98.3 REMARK 200 DATA REDUNDANCY IN SHELL : 4.90 REMARK 200 R MERGE FOR SHELL (I) : 0.70000 REMARK 200 R SYM FOR SHELL (I) : NULL REMARK 200 <I/SIGMA(I)> FOR SHELL : 1.900 REMARK 200 REMARK 200 DIFFRACTION PROTOCOL: SINGLE WAVELENGTH; SINGLE WAVELENGTH REMARK 200 METHOD USED TO DETERMINE THE STRUCTURE: MIR REMARK 200 SOFTWARE USED: PHASER REMARK 200 STARTING MODEL: PDB ENTRY 4BVN REMARK 200 REMARK 200 REMARK: NONE REMARK 280 REMARK 280 CRYSTAL REMARK 280 SOLVENT CONTENT, VS (%): 43.40 REMARK 280 MATTHEWS COEFFICIENT, VM (ANGSTROMS**3/DA): 2.17 REMARK 280 REMARK 280 CRYSTALLIZATION CONDITIONS: 25% PEG600, 0.1M ADA PH7.0, LIPIDIC REMARK 280 CUBIC PHASE (LCP), TEMPERATURE 293K REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY REMARK 290 SYMMETRY OPERATORS FOR SPACE GROUP: P 21 2 21 REMARK 290 REMARK 290 SYMOP SYMMETRY REMARK 290 NNNMMM OPERATOR REMARK 290 1555 X,Y,Z REMARK 290 2555 -X,Y,-Z REMARK 290 3555 X+1/2,-Y,-Z+1/2 REMARK 290 4555 -X+1/2,-Y,Z+1/2 REMARK 290 REMARK 290 WHERE NNN -> OPERATOR NUMBER REMARK 290 MMM -> TRANSLATION VECTOR REMARK 290 REMARK 290 CRYSTALLOGRAPHIC SYMMETRY TRANSFORMATIONS REMARK 290 THE FOLLOWING TRANSFORMATIONS OPERATE ON THE ATOM/HETATM REMARK 290 RECORDS IN THIS ENTRY TO PRODUCE CRYSTALLOGRAPHICALLY REMARK 290 RELATED MOLECULES. REMARK 290 SMTRY1 1 1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 1 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 1 0.000000 0.000000 1.000000 0.00000 REMARK 290 SMTRY1 2 -1.000000 0.000000 0.000000 0.00000 REMARK 290 SMTRY2 2 0.000000 1.000000 0.000000 0.00000 REMARK 290 SMTRY3 2 0.000000 0.000000 -1.000000 0.00000 REMARK 290 SMTRY1 3 1.000000 0.000000 0.000000 26.50950 REMARK 290 SMTRY2 3 0.000000 -1.000000 0.000000 0.00000 REMARK 290 SMTRY3 3 0.000000 0.000000 -1.000000 47.78050 REMARK 290 SMTRY1 4 -1.000000 0.000000 0.000000 26.50950 REMARK 290 SMTRY2 4 0.000000 -1.000000 0.000000 0.00000 REMARK 290 SMTRY3 4 0.000000 0.000000 1.000000 47.78050 REMARK 290 REMARK 290 REMARK: NULL REMARK 300 REMARK 300 BIOMOLECULE: 1 REMARK 300 SEE REMARK 350 FOR THE AUTHOR PROVIDED AND/OR PROGRAM REMARK 300 GENERATED ASSEMBLY INFORMATION FOR THE STRUCTURE IN REMARK 300 THIS ENTRY. THE REMARK MAY ALSO PROVIDE INFORMATION ON REMARK 300 BURIED SURFACE AREA. REMARK 350 REMARK 350 COORDINATES FOR A COMPLETE MULTIMER REPRESENTING THE KNOWN REMARK 350 BIOLOGICALLY SIGNIFICANT OLIGOMERIZATION STATE OF THE REMARK 350 MOLECULE CAN BE GENERATED BY APPLYING BIOMT TRANSFORMATIONS REMARK 350 GIVEN BELOW. BOTH NON-CRYSTALLOGRAPHIC AND REMARK 350 CRYSTALLOGRAPHIC OPERATIONS ARE GIVEN. REMARK 350 REMARK 350 BIOMOLECULE: 1 REMARK 350 AUTHOR DETERMINED BIOLOGICAL UNIT: MONOMERIC REMARK 350 SOFTWARE DETERMINED QUATERNARY STRUCTURE: MONOMERIC REMARK 350 SOFTWARE USED: PISA REMARK 350 APPLY THE FOLLOWING TO CHAINS: A REMARK 350 BIOMT1 1 1.000000 0.000000 0.000000 0.00000 REMARK 350 BIOMT2 1 0.000000 1.000000 0.000000 0.00000 REMARK 350 BIOMT3 1 0.000000 0.000000 1.000000 0.00000 REMARK 465 REMARK 465 MISSING RESIDUES REMARK 465 THE FOLLOWING RESIDUES WERE NOT LOCATED IN THE REMARK 465 EXPERIMENT. (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN REMARK 465 IDENTIFIER; SSSEQ=SEQUENCE NUMBER; I=INSERTION CODE.) REMARK 465 REMARK 465 M RES C SSSEQI REMARK 465 MET A 31 REMARK 465 GLY A 32 REMARK 465 ALA A 33 REMARK 465 GLU A 34 REMARK 465 LEU A 35 REMARK 465 ILE A 241 REMARK 465 ASP A 242 REMARK 465 ARG A 243 REMARK 465 ALA A 244 REMARK 465 SER A 245 REMARK 465 LYS A 246 REMARK 465 ARG A 355 REMARK 465 LEU A 356 REMARK 465 LEU A 357 REMARK 465 ALA A 358 REMARK 465 PHE A 359 REMARK 465 PRO A 360 REMARK 465 ARG A 361 REMARK 465 LYS A 362 REMARK 465 ALA A 363 REMARK 465 ASP A 364 REMARK 465 ARG A 365 REMARK 465 ARG A 366 REMARK 465 LEU A 367 REMARK 465 HIS A 368 REMARK 465 HIS A 369 REMARK 465 HIS A 370 REMARK 465 HIS A 371 REMARK 465 HIS A 372 REMARK 465 HIS A 373 REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: CLOSE CONTACTS REMARK 500 REMARK 500 THE FOLLOWING ATOMS THAT ARE RELATED BY CRYSTALLOGRAPHIC REMARK 500 SYMMETRY ARE IN CLOSE CONTACT. AN ATOM LOCATED WITHIN 0.15 REMARK 500 ANGSTROMS OF A SYMMETRY RELATED ATOM IS ASSUMED TO BE ON A REMARK 500 SPECIAL POSITION AND IS, THEREFORE, LISTED IN REMARK 375 REMARK 500 INSTEAD OF REMARK 500. ATOMS WITH NON-BLANK ALTERNATE REMARK 500 LOCATION INDICATORS ARE NOT INCLUDED IN THE CALCULATIONS. REMARK 500 REMARK 500 DISTANCE CUTOFF: REMARK 500 2.2 ANGSTROMS FOR CONTACTS NOT INVOLVING HYDROGEN ATOMS REMARK 500 1.6 ANGSTROMS FOR CONTACTS INVOLVING HYDROGEN ATOMS REMARK 500 REMARK 500 ATM1 RES C SSEQI ATM2 RES C SSEQI SSYMOP DISTANCE REMARK 500 OG SER A 145 OG SER A 145 2655 1.82 REMARK 500 REMARK 500 REMARK: NULL REMARK 500 REMARK 500 GEOMETRY AND STEREOCHEMISTRY REMARK 500 SUBTOPIC: TORSION ANGLES REMARK 500 REMARK 500 TORSION ANGLES OUTSIDE THE EXPECTED RAMACHANDRAN REGIONS: REMARK 500 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; REMARK 500 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE). REMARK 500 REMARK 500 STANDARD TABLE: REMARK 500 FORMAT:(10X,I3,1X,A3,1X,A1,I4,A1,4X,F7.2,3X,F7.2) REMARK 500 REMARK 500 EXPECTED VALUES: GJ KLEYWEGT AND TA JONES (1996). PHI/PSI- REMARK 500 CHOLOGY: RAMACHANDRAN REVISITED. STRUCTURE 4, 1395 - 1400 REMARK 500 REMARK 500 M RES CSSEQI PSI PHI REMARK 500 PHE A 216 -64.47 -139.87 REMARK 500 THR A 277 138.51 -37.27 REMARK 500 REMARK 500 REMARK: NULL REMARK 610 REMARK 610 MISSING HETEROATOM REMARK 610 THE FOLLOWING RESIDUES HAVE MISSING ATOMS (M=MODEL NUMBER; REMARK 610 RES=RESIDUE NAME; C=CHAIN IDENTIFIER; SSEQ=SEQUENCE NUMBER; REMARK 610 I=INSERTION CODE): REMARK 610 M RES C SSEQI REMARK 610 OLC A 2001 REMARK 610 OLC A 2003 REMARK 610 OLC A 2004 REMARK 620 REMARK 620 METAL COORDINATION REMARK 620 (M=MODEL NUMBER; RES=RESIDUE NAME; C=CHAIN IDENTIFIER; REMARK 620 SSEQ=SEQUENCE NUMBER; I=INSERTION CODE): REMARK 620 REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL REMARK 620 NA A 401 NA REMARK 620 N RES CSSEQI ATOM REMARK 620 1 HOH A3014 O REMARK 620 2 HOH A3015 O 96.5 REMARK 620 3 ASP A 195 O 163.7 82.3 REMARK 620 4 HOH A3009 O 101.4 79.7 94.4 REMARK 620 5 CYS A 192 O 95.7 109.0 69.6 159.9 REMARK 620 6 CYS A 198 O 99.8 151.3 88.3 74.0 92.8 REMARK 620 N 1 2 3 4 5 REMARK 620 REMARK 620 COORDINATION ANGLES FOR: M RES CSSEQI METAL REMARK 620 NA A 402 NA REMARK 620 N RES CSSEQI ATOM REMARK 620 1 ASP A 87 OD1 REMARK 620 2 HOH A3003 O 86.8 REMARK 620 3 HOH A3004 O 65.1 150.4 REMARK 620 4 HOH A3022 O 101.1 113.2 82.9 REMARK 620 5 SER A 128 OG 130.7 96.9 94.8 121.5 REMARK 620 N 1 2 3 4 REMARK 800 REMARK 800 SITE REMARK 800 SITE_IDENTIFIER: AC1 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE NA A 401 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC2 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE NA A 402 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC3 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE XTK A 501 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC4 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE MHA A 801 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC5 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE OLC A 2001 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC6 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE OLC A 2002 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC7 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE OLC A 2003 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC8 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE OLC A 2004 REMARK 800 REMARK 800 SITE_IDENTIFIER: AC9 REMARK 800 EVIDENCE_CODE: SOFTWARE REMARK 800 SITE_DESCRIPTION: BINDING SITE FOR RESIDUE OLC A 2005 REMARK 999 REMARK 999 SEQUENCE REMARK 999 THE FOLLOWING MUTATIONS WERE MADE TO IMPROVE REMARK 999 THERMOSTABILITY R68S,M90V,I129V,Y227A,A282L,F327A,F338M, REMARK 999 Y343L. THE FOLLOWING MUTATIONS WERE MADE TO IMPROVE REMARK 999 EXPRESSION AND HELP CRYSTALLIZATION C116L, E130W,C358A. DBREF 5A8E A 33 368 UNP P07700 ADRB1_MELGA 33 368 SEQADV 5A8E MET A 31 UNP P07700 EXPRESSION TAG SEQADV 5A8E GLY A 32 UNP P07700 EXPRESSION TAG SEQADV 5A8E HIS A 369 UNP P07700 EXPRESSION TAG SEQADV 5A8E HIS A 370 UNP P07700 EXPRESSION TAG SEQADV 5A8E HIS A 371 UNP P07700 EXPRESSION TAG SEQADV 5A8E HIS A 372 UNP P07700 EXPRESSION TAG SEQADV 5A8E HIS A 373 UNP P07700 EXPRESSION TAG SEQADV 5A8E SER A 68 UNP P07700 ARG 68 ENGINEERED MUTATION SEQADV 5A8E VAL A 90 UNP P07700 MET 90 ENGINEERED MUTATION SEQADV 5A8E LEU A 116 UNP P07700 CYS 116 ENGINEERED MUTATION SEQADV 5A8E VAL A 129 UNP P07700 ILE 129 ENGINEERED MUTATION SEQADV 5A8E TRP A 130 UNP P07700 GLU 130 ENGINEERED MUTATION SEQADV 5A8E ALA A 227 UNP P07700 TYR 227 ENGINEERED MUTATION SEQADV 5A8E LEU A 282 UNP P07700 ALA 282 ENGINEERED MUTATION SEQADV 5A8E ALA A 327 UNP P07700 PHE 327 ENGINEERED MUTATION SEQADV 5A8E MET A 338 UNP P07700 PHE 338 ENGINEERED MUTATION SEQADV 5A8E LEU A 343 UNP P07700 TYR 343 ENGINEERED MUTATION SEQADV 5A8E ALA A 358 UNP P07700 CYS 358 ENGINEERED MUTATION SEQRES 1 A 315 MET GLY ALA GLU LEU LEU SER GLN GLN TRP GLU ALA GLY SEQRES 2 A 315 MET SER LEU LEU MET ALA LEU VAL VAL LEU LEU ILE VAL SEQRES 3 A 315 ALA GLY ASN VAL LEU VAL ILE ALA ALA ILE GLY SER THR SEQRES 4 A 315 GLN ARG LEU GLN THR LEU THR ASN LEU PHE ILE THR SER SEQRES 5 A 315 LEU ALA CYS ALA ASP LEU VAL VAL GLY LEU LEU VAL VAL SEQRES 6 A 315 PRO PHE GLY ALA THR LEU VAL VAL ARG GLY THR TRP LEU SEQRES 7 A 315 TRP GLY SER PHE LEU CYS GLU LEU TRP THR SER LEU ASP SEQRES 8 A 315 VAL LEU CYS VAL THR ALA SER VAL TRP THR LEU CYS VAL SEQRES 9 A 315 ILE ALA ILE ASP ARG TYR LEU ALA ILE THR SER PRO PHE SEQRES 10 A 315 ARG TYR GLN SER LEU MET THR ARG ALA ARG ALA LYS VAL SEQRES 11 A 315 ILE ILE CYS THR VAL TRP ALA ILE SER ALA LEU VAL SER SEQRES 12 A 315 PHE LEU PRO ILE MET MET HIS TRP TRP ARG ASP GLU ASP SEQRES 13 A 315 PRO GLN ALA LEU LYS CYS TYR GLN ASP PRO GLY CYS CYS SEQRES 14 A 315 ASP PHE VAL THR ASN ARG ALA TYR ALA ILE ALA SER SER SEQRES 15 A 315 ILE ILE SER PHE TYR ILE PRO LEU LEU ILE MET ILE PHE SEQRES 16 A 315 VAL ALA LEU ARG VAL TYR ARG GLU ALA LYS GLU GLN ILE SEQRES 17 A 315 ARG LYS ILE ASP ARG ALA SER LYS ARG LYS THR SER ARG SEQRES 18 A 315 VAL MET LEU MET ARG GLU HIS LYS ALA LEU LYS THR LEU SEQRES 19 A 315 GLY ILE ILE MET GLY VAL PHE THR LEU CYS TRP LEU PRO SEQRES 20 A 315 PHE PHE LEU VAL ASN ILE VAL ASN VAL PHE ASN ARG ASP SEQRES 21 A 315 LEU VAL PRO ASP TRP LEU PHE VAL ALA PHE ASN TRP LEU SEQRES 22 A 315 GLY TYR ALA ASN SER ALA MET ASN PRO ILE ILE LEU CYS SEQRES 23 A 315 ARG SER PRO ASP PHE ARG LYS ALA PHE LYS ARG LEU LEU SEQRES 24 A 315 ALA PHE PRO ARG LYS ALA ASP ARG ARG LEU HIS HIS HIS SEQRES 25 A 315 HIS HIS HIS HET NA A 401 1 HET NA A 402 1 HET XTK A 501 22 HET MHA A 801 13 HET OLC A2001 16 HET OLC A2002 25 HET OLC A2003 13 HET OLC A2004 21 HET OLC A2005 25 HETNAM NA SODIUM ION HETNAM XTK 4-[(2S)-3-(TERT-BUTYLAMINO)-2-HYDROXYPROPOXY]-7-METHYL- HETNAM 2 XTK 1H-INDOLE-2-CARBONITRILE HETNAM MHA (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID HETNAM OLC (2R)-2,3-DIHYDROXYPROPYL (9Z)-OCTADEC-9-ENOATE HETSYN MHA N-(2-ACETAMIDO)IMINODIACETIC ACID HETSYN OLC 1-OLEOYL-R-GLYCEROL FORMUL 2 NA 2(NA 1+) FORMUL 4 XTK C17 H23 N3 O2 FORMUL 5 MHA C6 H10 N2 O5 FORMUL 6 OLC 5(C21 H40 O4) FORMUL 11 HOH *26(H2 O) HELIX 1 1 LEU A 36 SER A 68 1 33 HELIX 2 2 THR A 74 LEU A 93 1 20 HELIX 3 3 LEU A 93 GLY A 105 1 13 HELIX 4 4 TRP A 109 SER A 145 1 37 HELIX 5 5 SER A 145 MET A 153 1 9 HELIX 6 6 THR A 154 MET A 179 1 26 HELIX 7 7 ASP A 186 ASP A 195 1 10 HELIX 8 8 ASN A 204 PHE A 216 1 13 HELIX 9 9 PHE A 216 LYS A 240 1 25 HELIX 10 10 SER A 278 ASN A 316 1 39 HELIX 11 11 ARG A 317 VAL A 320 5 4 HELIX 12 12 PRO A 321 ARG A 345 1 25 HELIX 13 13 SER A 346 LYS A 354 1 9 SSBOND 1 CYS A 114 CYS A 199 1555 1555 2.04 SSBOND 2 CYS A 192 CYS A 198 1555 1555 2.06 LINK NA NA A 401 O HOH A3014 1555 1555 2.30 LINK NA NA A 401 O HOH A3015 1555 1555 2.33 LINK NA NA A 401 O ASP A 195 1555 1555 2.52 LINK NA NA A 401 O HOH A3009 1555 1555 2.69 LINK NA NA A 401 O CYS A 192 1555 1555 2.56 LINK NA NA A 401 O CYS A 198 1555 1555 2.31 LINK NA NA A 402 OD1 ASP A 87 1555 1555 2.60 LINK NA NA A 402 O HOH A3003 1555 1555 2.13 LINK NA NA A 402 O HOH A3004 1555 1555 2.57 LINK NA NA A 402 O HOH A3022 1555 1555 2.32 LINK NA NA A 402 OG SER A 128 1555 1555 2.46 SITE 1 AC1 6 CYS A 192 ASP A 195 CYS A 198 HOH A3009 SITE 2 AC1 6 HOH A3014 HOH A3015 SITE 1 AC2 5 ASP A 87 SER A 128 HOH A3003 HOH A3004 SITE 2 AC2 5 HOH A3022 SITE 1 AC3 13 TRP A 117 ASP A 121 VAL A 122 THR A 203 SITE 2 AC3 13 ALA A 208 SER A 211 SER A 215 TRP A 303 SITE 3 AC3 13 PHE A 306 PHE A 307 ASN A 310 ASN A 329 SITE 4 AC3 13 TYR A 333 SITE 1 AC4 10 GLY A 110 SER A 111 PRO A 196 LYS A 287 SITE 2 AC4 10 LYS A 290 THR A 291 ARG A 345 SER A 346 SITE 3 AC4 10 HOH A3008 HOH A3026 SITE 1 AC5 7 ALA A 227 ILE A 238 ARG A 239 HIS A 286 SITE 2 AC5 7 LEU A 289 GLY A 293 OLC A2002 SITE 1 AC6 8 TRP A 107 LEU A 108 ASP A 195 GLY A 197 SITE 2 AC6 8 LYS A 287 LYS A 290 GLY A 293 OLC A2001 SITE 1 AC7 1 TYR A 140 SITE 1 AC8 9 GLN A 73 THR A 74 LEU A 75 THR A 76 SITE 2 AC8 9 ARG A 139 ILE A 143 ARG A 155 GLU A 285 SITE 3 AC8 9 ALA A 288 SITE 1 AC9 6 TRP A 181 ASP A 184 ASN A 204 ARG A 205 SITE 2 AC9 6 LYS A 276 PHE A 315 CRYST1 53.019 61.777 95.561 90.00 90.00 90.00 P 21 2 21 4 ORIGX1 1.000000 0.000000 0.000000 0.00000 ORIGX2 0.000000 1.000000 0.000000 0.00000 ORIGX3 0.000000 0.000000 1.000000 0.00000 SCALE1 0.018861 0.000000 0.000000 0.00000 SCALE2 0.000000 0.016187 0.000000 0.00000 SCALE3 0.000000 0.000000 0.010465 0.00000 ATOM 1 N LEU A 36 28.465 41.894 43.339 1.00 95.49 N ATOM 2 CA LEU A 36 29.415 42.780 42.592 1.00 96.34 C ATOM 3 C LEU A 36 28.821 43.333 41.295 1.00 98.32 C ATOM 4 O LEU A 36 29.086 44.481 40.934 1.00 98.08 O ATOM 5 CB LEU A 36 30.721 42.036 42.290 1.00 95.56 C ATOM 6 CG LEU A 36 31.860 42.835 41.648 1.00 93.96 C ATOM 7 CD1 LEU A 36 32.237 44.039 42.502 1.00 93.87 C ATOM 8 CD2 LEU A 36 33.059 41.927 41.420 1.00 92.35 C ATOM 9 N SER A 37 28.048 42.506 40.591 1.00101.01 N ATOM 10 CA SER A 37 27.246 42.962 39.447 1.00103.08 C ATOM 11 C SER A 37 26.144 43.941 39.879 1.00106.54 C ATOM 12 O SER A 37 25.751 44.816 39.102 1.00110.44 O ATOM 13 CB SER A 37 26.626 41.768 38.715 1.00102.13 C ATOM 14 OG SER A 37 25.752 41.043 39.563 1.00100.54 O ATOM 15 N GLN A 38 25.648 43.776 41.108 1.00106.92 N ATOM 16 CA GLN A 38 24.687 44.704 41.718 1.00104.39 C ATOM 17 C GLN A 38 25.318 46.065 42.046 1.00100.89 C ATOM 18 O GLN A 38 24.659 47.098 41.910 1.00100.30 O ATOM 19 CB GLN A 38 24.085 44.081 42.987 1.00105.47 C ATOM 20 CG GLN A 38 22.888 44.818 43.583 1.00107.19 C ATOM 21 CD GLN A 38 21.582 44.588 42.832 1.00107.23 C ATOM 22 OE1 GLN A 38 21.571 44.151 41.678 1.00105.69 O ATOM 23 NE2 GLN A 38 20.465 44.888 43.492 1.00106.18 N ATOM 24 N GLN A 39 26.575 46.060 42.492 1.00 97.65 N ATOM 25 CA GLN A 39 27.335 47.304 42.715 1.00 96.16 C ATOM 26 C GLN A 39 27.554 48.091 41.417 1.00 91.92 C ATOM 27 O GLN A 39 27.482 49.323 41.417 1.00 95.05 O ATOM 28 CB GLN A 39 28.690 47.015 43.388 1.00 97.89 C ATOM 29 CG GLN A 39 28.608 46.772 44.892 1.00 98.12 C ATOM 30 CD GLN A 39 28.329 48.034 45.699 1.00 99.98 C ATOM 31 OE1 GLN A 39 28.327 49.146 45.168 1.00101.20 O ATOM 32 NE2 GLN A 39 28.091 47.862 46.997 1.00102.41 N ATOM 33 N TRP A 40 27.821 47.374 40.325 1.00 84.81 N ATOM 34 CA TRP A 40 27.959 47.980 38.997 1.00 80.04 C ATOM 35 C TRP A 40 26.609 48.458 38.442 1.00 79.29 C ATOM 36 O TRP A 40 26.532 49.539 37.859 1.00 77.91 O ATOM 37 CB TRP A 40 28.602 46.985 38.030 1.00 77.44 C ATOM 38 CG TRP A 40 29.028 47.584 36.733 1.00 74.53 C ATOM 39 CD1 TRP A 40 30.121 48.369 36.516 1.00 75.76 C ATOM 40 CD2 TRP A 40 28.381 47.433 35.466 1.00 72.52 C ATOM 41 NE1 TRP A 40 30.193 48.725 35.191 1.00 75.39 N ATOM 42 CE2 TRP A 40 29.138 48.164 34.522 1.00 73.45 C ATOM 43 CE3 TRP A 40 27.232 46.755 35.035 1.00 70.42 C ATOM 44 CZ2 TRP A 40 28.785 48.235 33.168 1.00 72.88 C ATOM 45 CZ3 TRP A 40 26.882 46.824 33.689 1.00 70.07 C ATOM 46 CH2 TRP A 40 27.657 47.562 32.772 1.00 71.32 C ATOM 47 N GLU A 41 25.563 47.646 38.614 1.00 77.53 N ATOM 48 CA GLU A 41 24.189 48.040 38.249 1.00 77.61 C ATOM 49 C GLU A 41 23.729 49.294 38.992 1.00 76.92 C ATOM 50 O GLU A 41 23.213 50.226 38.378 1.00 79.25 O ATOM 51 CB GLU A 41 23.178 46.911 38.519 1.00 78.13 C ATOM 52 CG GLU A 41 22.967 45.943 37.362 1.00 79.52 C ATOM 53 CD GLU A 41 21.689 45.129 37.502 1.00 80.73 C ATOM 54 OE1 GLU A 41 21.292 44.818 38.646 1.00 82.13 O ATOM 55 OE2 GLU A 41 21.079 44.795 36.465 1.00 79.02 O ATOM 56 N ALA A 42 23.908 49.293 40.312 1.00 74.80 N ATOM 57 CA ALA A 42 23.539 50.430 41.162 1.00 72.88 C ATOM 58 C ALA A 42 24.417 51.651 40.895 1.00 71.01 C ATOM 59 O ALA A 42 23.925 52.781 40.914 1.00 68.72 O ATOM 60 CB ALA A 42 23.622 50.043 42.631 1.00 72.21 C ATOM 61 N GLY A 43 25.708 51.410 40.658 1.00 70.42 N ATOM 62 CA GLY A 43 26.675 52.464 40.352 1.00 69.59 C ATOM 63 C GLY A 43 26.413 53.139 39.021 1.00 68.87 C ATOM 64 O GLY A 43 26.407 54.369 38.938 1.00 68.15 O ATOM 65 N MET A 44 26.192 52.332 37.982 1.00 68.75 N ATOM 66 CA MET A 44 25.886 52.850 36.644 1.00 68.25 C ATOM 67 C MET A 44 24.505 53.511 36.589 1.00 65.63 C ATOM 68 O MET A 44 24.368 54.578 36.000 1.00 67.05 O ATOM 69 CB MET A 44 26.002 51.754 35.575 1.00 70.30 C ATOM 70 CG MET A 44 27.432 51.347 35.233 1.00 72.50 C ATOM 71 SD MET A 44 28.340 52.635 34.352 1.00 76.15 S ATOM 72 CE MET A 44 29.555 51.689 33.437 1.00 77.41 C ATOM 73 N SER A 45 23.500 52.893 37.213 1.00 60.80 N ATOM 74 CA SER A 45 22.155 53.491 37.337 1.00 59.80 C ATOM 75 C SER A 45 22.177 54.954 37.791 1.00 59.01 C ATOM 76 O SER A 45 21.507 55.799 37.194 1.00 59.92 O ATOM 77 CB SER A 45 21.284 52.689 38.315 1.00 59.81 C ATOM 78 OG SER A 45 20.833 51.476 37.738 1.00 60.22 O ATOM 79 N LEU A 46 22.947 55.235 38.841 1.00 57.60 N ATOM 80 CA LEU A 46 23.053 56.586 39.407 1.00 57.57 C ATOM 81 C LEU A 46 23.804 57.538 38.478 1.00 55.82 C ATOM 82 O LEU A 46 23.376 58.676 38.291 1.00 57.37 O ATOM 83 CB LEU A 46 23.734 56.545 40.785 1.00 59.48 C ATOM 84 CG LEU A 46 23.967 57.868 41.531 1.00 60.40 C ATOM 85 CD1 LEU A 46 22.669 58.634 41.750 1.00 60.27 C ATOM 86 CD2 LEU A 46 24.662 57.601 42.856 1.00 60.58 C ATOM 87 N LEU A 47 24.923 57.072 37.920 1.00 53.55 N ATOM 88 CA LEU A 47 25.688 57.830 36.912 1.00 53.05 C ATOM 89 C LEU A 47 24.842 58.201 35.677 1.00 51.13 C ATOM 90 O LEU A 47 24.995 59.291 35.124 1.00 48.78 O ATOM 91 CB LEU A 47 26.943 57.045 36.482 1.00 53.61 C ATOM 92 CG LEU A 47 27.733 57.523 35.252 1.00 55.98 C ATOM 93 CD1 LEU A 47 28.274 58.936 35.431 1.00 56.88 C ATOM 94 CD2 LEU A 47 28.869 56.558 34.946 1.00 56.75 C ATOM 95 N MET A 48 23.963 57.293 35.253 1.00 49.36 N ATOM 96 CA MET A 48 23.076 57.550 34.115 1.00 48.89 C ATOM 97 C MET A 48 21.985 58.566 34.465 1.00 47.54 C ATOM 98 O MET A 48 21.639 59.403 33.635 1.00 48.58 O ATOM 99 CB MET A 48 22.442 56.251 33.608 1.00 49.38 C ATOM 100 CG MET A 48 23.432 55.218 33.083 1.00 50.41 C ATOM 101 SD MET A 48 24.322 55.700 31.599 1.00 51.09 S ATOM 102 CE MET A 48 25.085 54.139 31.159 1.00 51.53 C ATOM 103 N ALA A 49 21.449 58.490 35.683 1.00 45.83 N ATOM 104 CA ALA A 49 20.487 59.482 36.175 1.00 44.76 C ATOM 105 C ALA A 49 21.071 60.898 36.155 1.00 44.71 C ATOM 106 O ALA A 49 20.396 61.834 35.732 1.00 44.69 O ATOM 107 CB ALA A 49 20.028 59.124 37.579 1.00 44.90 C ATOM 108 N LEU A 50 22.324 61.039 36.593 1.00 44.83 N ATOM 109 CA LEU A 50 23.034 62.326 36.563 1.00 44.94 C ATOM 110 C LEU A 50 23.302 62.836 35.141 1.00 42.75 C ATOM 111 O LEU A 50 23.168 64.034 34.880 1.00 42.89 O ATOM 112 CB LEU A 50 24.358 62.247 37.344 1.00 46.73 C ATOM 113 CG LEU A 50 24.294 61.962 38.854 1.00 49.21 C ATOM 114 CD1 LEU A 50 25.664 62.177 39.485 1.00 49.05 C ATOM 115 CD2 LEU A 50 23.244 62.815 39.563 1.00 50.46 C ATOM 116 N VAL A 51 23.677 61.937 34.233 1.00 40.34 N ATOM 117 CA VAL A 51 23.817 62.288 32.808 1.00 39.36 C ATOM 118 C VAL A 51 22.478 62.778 32.225 1.00 37.07 C ATOM 119 O VAL A 51 22.434 63.815 31.556 1.00 33.30 O ATOM 120 CB VAL A 51 24.385 61.109 31.982 1.00 39.68 C ATOM 121 CG1 VAL A 51 24.245 61.351 30.483 1.00 40.02 C ATOM 122 CG2 VAL A 51 25.851 60.881 32.332 1.00 40.24 C ATOM 123 N VAL A 52 21.402 62.037 32.495 1.00 36.53 N ATOM 124 CA VAL A 52 20.051 62.427 32.059 1.00 38.00 C ATOM 125 C VAL A 52 19.694 63.816 32.605 1.00 38.83 C ATOM 126 O VAL A 52 19.254 64.688 31.848 1.00 39.37 O ATOM 127 CB VAL A 52 18.967 61.398 32.485 1.00 37.46 C ATOM 128 CG1 VAL A 52 17.556 61.933 32.236 1.00 37.03 C ATOM 129 CG2 VAL A 52 19.146 60.078 31.744 1.00 37.63 C ATOM 130 N LEU A 53 19.897 64.012 33.909 1.00 39.01 N ATOM 131 CA LEU A 53 19.589 65.288 34.563 1.00 39.99 C ATOM 132 C LEU A 53 20.388 66.453 33.973 1.00 38.31 C ATOM 133 O LEU A 53 19.840 67.528 33.752 1.00 40.00 O ATOM 134 CB LEU A 53 19.841 65.200 36.076 1.00 42.05 C ATOM 135 CG LEU A 53 19.514 66.445 36.922 1.00 42.70 C ATOM 136 CD1 LEU A 53 18.035 66.773 36.844 1.00 42.49 C ATOM 137 CD2 LEU A 53 19.948 66.256 38.370 1.00 43.29 C ATOM 138 N LEU A 54 21.676 66.235 33.733 1.00 36.01 N ATOM 139 CA LEU A 54 22.544 67.254 33.135 1.00 34.44 C ATOM 140 C LEU A 54 22.109 67.608 31.715 1.00 31.85 C ATOM 141 O LEU A 54 22.004 68.782 31.374 1.00 30.69 O ATOM 142 CB LEU A 54 23.998 66.764 33.126 1.00 35.74 C ATOM 143 CG LEU A 54 25.089 67.719 32.630 1.00 36.68 C ATOM 144 CD1 LEU A 54 25.260 68.886 33.593 1.00 36.56 C ATOM 145 CD2 LEU A 54 26.403 66.972 32.451 1.00 36.59 C ATOM 146 N ILE A 55 21.865 66.592 30.891 1.00 31.03 N ATOM 147 CA ILE A 55 21.436 66.808 29.504 1.00 30.36 C ATOM 148 C ILE A 55 20.076 67.500 29.469 1.00 30.07 C ATOM 149 O ILE A 55 19.905 68.486 28.754 1.00 29.60 O ATOM 150 CB ILE A 55 21.374 65.484 28.690 1.00 30.14 C ATOM 151 CG1 ILE A 55 22.787 64.925 28.470 1.00 29.87 C ATOM 152 CG2 ILE A 55 20.687 65.698 27.338 1.00 29.91 C ATOM 153 CD1 ILE A 55 22.827 63.480 28.011 1.00 29.78 C ATOM 154 N VAL A 56 19.117 66.980 30.237 1.00 30.05 N ATOM 155 CA VAL A 56 17.745 67.503 30.215 1.00 30.04 C ATOM 156 C VAL A 56 17.678 68.905 30.826 1.00 29.98 C ATOM 157 O VAL A 56 17.159 69.819 30.185 1.00 30.68 O ATOM 158 CB VAL A 56 16.745 66.553 30.912 1.00 30.51 C ATOM 159 CG1 VAL A 56 15.368 67.201 31.045 1.00 30.36 C ATOM 160 CG2 VAL A 56 16.629 65.242 30.138 1.00 30.15 C ATOM 161 N ALA A 57 18.206 69.079 32.039 1.00 28.65 N ATOM 162 CA ALA A 57 18.163 70.386 32.711 1.00 28.36 C ATOM 163 C ALA A 57 18.977 71.429 31.959 1.00 27.60 C ATOM 164 O ALA A 57 18.520 72.569 31.785 1.00 28.81 O ATOM 165 CB ALA A 57 18.645 70.290 34.154 1.00 28.39 C ATOM 166 N GLY A 58 20.179 71.043 31.534 1.00 25.68 N ATOM 167 CA GLY A 58 21.040 71.914 30.756 1.00 24.84 C ATOM 168 C GLY A 58 20.331 72.456 29.533 1.00 24.45 C ATOM 169 O GLY A 58 20.298 73.667 29.312 1.00 24.68 O ATOM 170 N ASN A 59 19.728 71.568 28.754 1.00 24.49 N ATOM 171 CA ASN A 59 19.068 71.985 27.507 1.00 25.16 C ATOM 172 C ASN A 59 17.715 72.690 27.669 1.00 26.01 C ATOM 173 O ASN A 59 17.337 73.485 26.798 1.00 26.38 O ATOM 174 CB ASN A 59 19.018 70.833 26.505 1.00 24.90 C ATOM 175 CG ASN A 59 20.373 70.595 25.855 1.00 24.89 C ATOM 176 OD1 ASN A 59 20.794 71.370 25.006 1.00 25.42 O ATOM 177 ND2 ASN A 59 21.070 69.544 26.267 1.00 24.92 N ATOM 178 N VAL A 60 17.008 72.446 28.776 1.00 26.90 N ATOM 179 CA VAL A 60 15.831 73.265 29.111 1.00 27.39 C ATOM 180 C VAL A 60 16.253 74.711 29.466 1.00 27.52 C ATOM 181 O VAL A 60 15.597 75.676 29.046 1.00 26.46 O ATOM 182 CB VAL A 60 14.988 72.663 30.260 1.00 28.24 C ATOM 183 CG1 VAL A 60 13.819 73.575 30.607 1.00 28.37 C ATOM 184 CG2 VAL A 60 14.441 71.292 29.885 1.00 28.90 C ATOM 185 N LEU A 61 17.334 74.858 30.232 1.00 27.92 N ATOM 186 CA LEU A 61 17.822 76.189 30.629 1.00 29.17 C ATOM 187 C LEU A 61 18.184 77.040 29.418 1.00 29.23 C ATOM 188 O LEU A 61 17.763 78.200 29.324 1.00 28.45 O ATOM 189 CB LEU A 61 19.030 76.104 31.580 1.00 30.31 C ATOM 190 CG LEU A 61 18.728 75.903 33.068 1.00 32.45 C ATOM 191 CD1 LEU A 61 20.021 75.649 33.828 1.00 32.89 C ATOM 192 CD2 LEU A 61 17.990 77.106 33.657 1.00 33.02 C ATOM 193 N VAL A 62 18.951 76.449 28.499 1.00 28.28 N ATOM 194 CA VAL A 62 19.322 77.094 27.235 1.00 27.30 C ATOM 195 C VAL A 62 18.080 77.615 26.524 1.00 27.29 C ATOM 196 O VAL A 62 18.020 78.782 26.147 1.00 26.96 O ATOM 197 CB VAL A 62 20.104 76.114 26.324 1.00 26.90 C ATOM 198 CG1 VAL A 62 20.189 76.606 24.880 1.00 26.56 C ATOM 199 CG2 VAL A 62 21.501 75.898 26.884 1.00 26.93 C ATOM 200 N ILE A 63 17.089 76.742 26.367 1.00 28.01 N ATOM 201 CA ILE A 63 15.825 77.099 25.717 1.00 28.09 C ATOM 202 C ILE A 63 15.050 78.155 26.538 1.00 28.19 C ATOM 203 O ILE A 63 14.457 79.065 25.962 1.00 27.89 O ATOM 204 CB ILE A 63 14.966 75.840 25.444 1.00 28.39 C ATOM 205 CG1 ILE A 63 15.688 74.909 24.458 1.00 28.51 C ATOM 206 CG2 ILE A 63 13.611 76.220 24.854 1.00 28.78 C ATOM 207 CD1 ILE A 63 15.191 73.479 24.466 1.00 28.45 C ATOM 208 N ALA A 64 15.075 78.029 27.868 1.00 28.48 N ATOM 209 CA ALA A 64 14.467 79.012 28.785 1.00 28.30 C ATOM 210 C ALA A 64 15.190 80.364 28.799 1.00 29.02 C ATOM 211 O ALA A 64 14.561 81.400 28.968 1.00 28.62 O ATOM 212 CB ALA A 64 14.412 78.450 30.197 1.00 27.95 C ATOM 213 N ALA A 65 16.513 80.343 28.659 1.00 30.59 N ATOM 214 CA ALA A 65 17.305 81.561 28.528 1.00 31.46 C ATOM 215 C ALA A 65 16.931 82.306 27.259 1.00 33.85 C ATOM 216 O ALA A 65 16.761 83.527 27.283 1.00 36.82 O ATOM 217 CB ALA A 65 18.789 81.236 28.520 1.00 31.29 C ATOM 218 N ILE A 66 16.786 81.567 26.160 1.00 34.74 N ATOM 219 CA ILE A 66 16.485 82.164 24.856 1.00 35.69 C ATOM 220 C ILE A 66 15.063 82.742 24.832 1.00 37.33 C ATOM 221 O ILE A 66 14.857 83.854 24.344 1.00 38.07 O ATOM 222 CB ILE A 66 16.717 81.157 23.697 1.00 34.44 C ATOM 223 CG1 ILE A 66 18.205 80.796 23.613 1.00 34.19 C ATOM 224 CG2 ILE A 66 16.262 81.743 22.362 1.00 33.98 C ATOM 225 CD1 ILE A 66 18.502 79.545 22.818 1.00 34.32 C ATOM 226 N GLY A 67 14.101 81.997 25.373 1.00 38.75 N ATOM 227 CA GLY A 67 12.697 82.418 25.384 1.00 40.23 C ATOM 228 C GLY A 67 12.299 83.480 26.403 1.00 42.37 C ATOM 229 O GLY A 67 11.216 84.060 26.289 1.00 42.56 O ATOM 230 N SER A 68 13.145 83.730 27.406 1.00 44.71 N ATOM 231 CA SER A 68 12.829 84.691 28.473 1.00 46.18 C ATOM 232 C SER A 68 13.681 85.965 28.447 1.00 47.05 C ATOM 233 O SER A 68 13.681 86.718 29.426 1.00 47.81 O ATOM 234 CB SER A 68 12.988 84.013 29.834 1.00 47.05 C ATOM 235 OG SER A 68 14.353 83.930 30.208 1.00 47.75 O ATOM 236 N THR A 69 14.391 86.211 27.344 1.00 47.88 N ATOM 237 CA THR A 69 15.367 87.301 27.270 1.00 48.97 C ATOM 238 C THR A 69 15.342 87.961 25.890 1.00 52.36 C ATOM 239 O THR A 69 15.476 87.278 24.878 1.00 51.21 O ATOM 240 CB THR A 69 16.801 86.789 27.558 1.00 47.82 C ATOM 241 OG1 THR A 69 16.782 85.856 28.645 1.00 46.46 O ATOM 242 CG2 THR A 69 17.731 87.941 27.912 1.00 47.84 C ATOM 243 N GLN A 70 15.182 89.287 25.874 1.00 56.50 N ATOM 244 CA GLN A 70 15.181 90.101 24.644 1.00 59.91 C ATOM 245 C GLN A 70 16.504 90.014 23.877 1.00 59.86 C ATOM 246 O GLN A 70 16.507 89.831 22.660 1.00 57.80 O ATOM 247 CB GLN A 70 14.881 91.575 24.999 1.00 62.94 C ATOM 248 CG GLN A 70 14.994 92.594 23.864 1.00 64.60 C ATOM 249 CD GLN A 70 14.055 92.312 22.702 1.00 67.08 C ATOM 250 OE1 GLN A 70 12.935 91.833 22.896 1.00 67.93 O ATOM 251 NE2 GLN A 70 14.499 92.628 21.485 1.00 68.68 N ATOM 252 N ARG A 71 17.611 90.176 24.603 1.00 62.74 N ATOM 253 CA ARG A 71 18.970 90.095 24.037 1.00 64.27 C ATOM 254 C ARG A 71 19.247 88.805 23.252 1.00 61.83 C ATOM 255 O ARG A 71 19.946 88.842 22.235 1.00 59.91 O ATOM 256 CB ARG A 71 20.025 90.228 25.146 1.00 69.17 C ATOM 257 CG ARG A 71 20.352 91.654 25.565 1.00 72.82 C ATOM 258 CD ARG A 71 21.195 91.657 26.838 1.00 76.90 C ATOM 259 NE ARG A 71 22.202 92.722 26.882 1.00 79.59 N ATOM 260 CZ ARG A 71 23.035 92.944 27.904 1.00 81.51 C ATOM 261 NH1 ARG A 71 23.000 92.182 29.000 1.00 83.06 N ATOM 262 NH2 ARG A 71 23.914 93.941 27.834 1.00 81.30 N ATOM 263 N LEU A 72 18.700 87.680 23.727 1.00 57.77 N ATOM 264 CA LEU A 72 18.912 86.366 23.096 1.00 55.02 C ATOM 265 C LEU A 72 17.879 85.991 22.006 1.00 54.16 C ATOM 266 O LEU A 72 17.874 84.848 21.536 1.00 52.26 O ATOM 267 CB LEU A 72 18.981 85.275 24.180 1.00 53.96 C ATOM 268 CG LEU A 72 20.101 85.408 25.223 1.00 52.91 C ATOM 269 CD1 LEU A 72 19.961 84.327 26.282 1.00 52.20 C ATOM 270 CD2 LEU A 72 21.482 85.343 24.586 1.00 52.39 C ATOM 271 N GLN A 73 17.049 86.945 21.570 1.00 52.78 N ATOM 272 CA GLN A 73 16.065 86.710 20.503 1.00 53.33 C ATOM 273 C GLN A 73 16.654 86.955 19.107 1.00 51.49 C ATOM 274 O GLN A 73 16.092 87.710 18.310 1.00 52.38 O ATOM 275 CB GLN A 73 14.824 87.596 20.709 1.00 55.81 C ATOM 276 CG GLN A 73 13.974 87.205 21.900 1.00 56.73 C ATOM 277 CD GLN A 73 13.158 85.960 21.629 1.00 58.82 C ATOM 278 OE1 GLN A 73 12.078 86.033 21.038 1.00 61.91 O ATOM 279 NE2 GLN A 73 13.673 84.806 22.048 1.00 60.09 N ATOM 280 N THR A 74 17.772 86.297 18.808 1.00 48.05 N ATOM 281 CA THR A 74 18.421 86.397 17.504 1.00 45.86 C ATOM 282 C THR A 74 18.027 85.202 16.637 1.00 45.22 C ATOM 283 O THR A 74 17.511 84.200 17.144 1.00 46.13 O ATOM 284 CB THR A 74 19.951 86.467 17.649 1.00 44.48 C ATOM 285 OG1 THR A 74 20.416 85.365 18.436 1.00 43.25 O ATOM 286 CG2 THR A 74 20.355 87.771 18.320 1.00 43.97 C ATOM 287 N LEU A 75 18.254 85.327 15.330 1.00 43.60 N ATOM 288 CA LEU A 75 17.964 84.247 14.376 1.00 42.99 C ATOM 289 C LEU A 75 18.819 83.012 14.636 1.00 40.77 C ATOM 290 O LEU A 75 18.326 81.884 14.582 1.00 37.83 O ATOM 291 CB LEU A 75 18.182 84.722 12.936 1.00 44.51 C ATOM 292 CG LEU A 75 17.102 85.664 12.403 1.00 45.31 C ATOM 293 CD1 LEU A 75 17.615 86.516 11.253 1.00 46.82 C ATOM 294 CD2 LEU A 75 15.889 84.870 11.964 1.00 45.81 C ATOM 295 N THR A 76 20.099 83.243 14.912 1.00 39.32 N ATOM 296 CA THR A 76 21.033 82.181 15.262 1.00 39.69 C ATOM 297 C THR A 76 20.554 81.354 16.454 1.00 38.22 C ATOM 298 O THR A 76 20.643 80.127 16.429 1.00 36.92 O ATOM 299 CB THR A 76 22.430 82.760 15.556 1.00 40.76 C ATOM 300 OG1 THR A 76 22.886 83.488 14.406 1.00 43.58 O ATOM 301 CG2 THR A 76 23.429 81.663 15.866 1.00 41.00 C ATOM 302 N ASN A 77 20.043 82.021 17.486 1.00 37.08 N ATOM 303 CA ASN A 77 19.559 81.322 18.681 1.00 36.28 C ATOM 304 C ASN A 77 18.281 80.501 18.466 1.00 36.49 C ATOM 305 O ASN A 77 18.004 79.580 19.240 1.00 36.02 O ATOM 306 CB ASN A 77 19.410 82.293 19.858 1.00 36.37 C ATOM 307 CG ASN A 77 20.749 82.675 20.475 1.00 35.84 C ATOM 308 OD1 ASN A 77 21.791 82.102 20.154 1.00 36.49 O ATOM 309 ND2 ASN A 77 20.724 83.639 21.374 1.00 36.16 N ATOM 310 N LEU A 78 17.513 80.827 17.425 1.00 37.18 N ATOM 311 CA LEU A 78 16.460 79.929 16.938 1.00 37.50 C ATOM 312 C LEU A 78 17.052 78.649 16.359 1.00 35.61 C ATOM 313 O LEU A 78 16.492 77.571 16.561 1.00 35.72 O ATOM 314 CB LEU A 78 15.551 80.605 15.900 1.00 40.31 C ATOM 315 CG LEU A 78 14.273 81.230 16.458 1.00 43.15 C ATOM 316 CD1 LEU A 78 14.584 82.347 17.443 1.00 44.06 C ATOM 317 CD2 LEU A 78 13.420 81.745 15.308 1.00 45.09 C ATOM 318 N PHE A 79 18.165 78.765 15.633 1.00 33.80 N ATOM 319 CA PHE A 79 18.905 77.577 15.189 1.00 33.23 C ATOM 320 C PHE A 79 19.543 76.819 16.364 1.00 31.78 C ATOM 321 O PHE A 79 19.568 75.583 16.352 1.00 31.13 O ATOM 322 CB PHE A 79 19.956 77.912 14.121 1.00 33.37 C ATOM 323 CG PHE A 79 19.379 78.494 12.857 1.00 34.08 C ATOM 324 CD1 PHE A 79 18.381 77.825 12.157 1.00 34.96 C ATOM 325 CD2 PHE A 79 19.850 79.704 12.349 1.00 34.23 C ATOM 326 CE1 PHE A 79 17.847 78.360 10.993 1.00 35.56 C ATOM 327 CE2 PHE A 79 19.325 80.242 11.185 1.00 34.68 C ATOM 328 CZ PHE A 79 18.321 79.569 10.505 1.00 35.40 C ATOM 329 N ILE A 80 20.042 77.547 17.368 1.00 29.98 N ATOM 330 CA ILE A 80 20.517 76.932 18.627 1.00 30.20 C ATOM 331 C ILE A 80 19.406 76.117 19.306 1.00 29.24 C ATOM 332 O ILE A 80 19.669 75.037 19.841 1.00 27.80 O ATOM 333 CB ILE A 80 21.079 77.992 19.621 1.00 31.16 C ATOM 334 CG1 ILE A 80 22.396 78.598 19.109 1.00 31.73 C ATOM 335 CG2 ILE A 80 21.280 77.430 21.029 1.00 31.81 C ATOM 336 CD1 ILE A 80 23.555 77.625 19.006 1.00 32.69 C ATOM 337 N THR A 81 18.176 76.639 19.283 1.00 28.76 N ATOM 338 CA THR A 81 17.016 75.944 19.862 1.00 28.15 C ATOM 339 C THR A 81 16.773 74.562 19.232 1.00 27.13 C ATOM 340 O THR A 81 16.378 73.635 19.939 1.00 25.67 O ATOM 341 CB THR A 81 15.749 76.829 19.791 1.00 29.00 C ATOM 342 OG1 THR A 81 15.975 78.022 20.555 1.00 29.68 O ATOM 343 CG2 THR A 81 14.523 76.117 20.352 1.00 29.78 C ATOM 344 N SER A 82 17.030 74.429 17.925 1.00 26.49 N ATOM 345 CA SER A 82 16.918 73.136 17.222 1.00 26.02 C ATOM 346 C SER A 82 17.929 72.113 17.752 1.00 25.77 C ATOM 347 O SER A 82 17.572 70.954 17.992 1.00 25.24 O ATOM 348 CB SER A 82 17.072 73.320 15.702 1.00 26.71 C ATOM 349 OG SER A 82 17.319 72.093 15.029 1.00 26.81 O ATOM 350 N LEU A 83 19.175 72.546 17.945 1.00 25.64 N ATOM 351 CA LEU A 83 20.209 71.698 18.560 1.00 26.27 C ATOM 352 C LEU A 83 19.802 71.296 19.958 1.00 25.30 C ATOM 353 O LEU A 83 19.874 70.122 20.317 1.00 25.06 O ATOM 354 CB LEU A 83 21.562 72.408 18.636 1.00 27.24 C ATOM 355 CG LEU A 83 22.225 72.773 17.313 1.00 28.37 C ATOM 356 CD1 LEU A 83 23.342 73.778 17.543 1.00 29.62 C ATOM 357 CD2 LEU A 83 22.756 71.528 16.624 1.00 29.04 C ATOM 358 N ALA A 84 19.366 72.281 20.736 1.00 25.65 N ATOM 359 CA ALA A 84 18.861 72.050 22.094 1.00 25.97 C ATOM 360 C ALA A 84 17.697 71.059 22.130 1.00 26.14 C ATOM 361 O ALA A 84 17.617 70.259 23.049 1.00 26.93 O ATOM 362 CB ALA A 84 18.453 73.368 22.742 1.00 26.10 C ATOM 363 N CYS A 85 16.804 71.116 21.140 1.00 26.93 N ATOM 364 CA CYS A 85 15.706 70.148 21.025 1.00 28.00 C ATOM 365 C CYS A 85 16.220 68.737 20.739 1.00 29.06 C ATOM 366 O CYS A 85 15.727 67.761 21.322 1.00 29.48 O ATOM 367 CB CYS A 85 14.710 70.555 19.930 1.00 28.56 C ATOM 368 SG CYS A 85 13.624 71.927 20.376 1.00 29.79 S ATOM 369 N ALA A 86 17.197 68.631 19.837 1.00 29.28 N ATOM 370 CA ALA A 86 17.827 67.348 19.532 1.00 29.13 C ATOM 371 C ALA A 86 18.555 66.785 20.750 1.00 29.19 C ATOM 372 O ALA A 86 18.464 65.598 21.025 1.00 30.35 O ATOM 373 CB ALA A 86 18.779 67.481 18.353 1.00 29.27 C ATOM 374 N ASP A 87 19.269 67.630 21.482 1.00 29.46 N ATOM 375 CA ASP A 87 19.931 67.188 22.720 1.00 31.19 C ATOM 376 C ASP A 87 18.920 66.764 23.799 1.00 30.98 C ATOM 377 O ASP A 87 19.166 65.829 24.564 1.00 30.25 O ATOM 378 CB ASP A 87 20.863 68.284 23.250 1.00 32.48 C ATOM 379 CG ASP A 87 22.026 68.583 22.300 1.00 34.32 C ATOM 380 OD1 ASP A 87 22.409 67.686 21.513 1.00 34.04 O ATOM 381 OD2 ASP A 87 22.568 69.713 22.341 1.00 37.33 O ATOM 382 N LEU A 88 17.777 67.442 23.829 1.00 30.90 N ATOM 383 CA LEU A 88 16.690 67.124 24.761 1.00 31.32 C ATOM 384 C LEU A 88 16.042 65.763 24.467 1.00 30.52 C ATOM 385 O LEU A 88 15.765 64.996 25.393 1.00 30.53 O ATOM 386 CB LEU A 88 15.630 68.236 24.723 1.00 31.95 C ATOM 387 CG LEU A 88 14.770 68.528 25.944 1.00 32.05 C ATOM 388 CD1 LEU A 88 15.621 68.731 27.187 1.00 32.57 C ATOM 389 CD2 LEU A 88 13.944 69.772 25.655 1.00 31.73 C ATOM 390 N VAL A 89 15.812 65.461 23.187 1.00 29.00 N ATOM 391 CA VAL A 89 15.292 64.141 22.788 1.00 28.12 C ATOM 392 C VAL A 89 16.283 63.029 23.159 1.00 27.45 C ATOM 393 O VAL A 89 15.880 61.957 23.606 1.00 28.15 O ATOM 394 CB VAL A 89 14.916 64.102 21.286 1.00 28.48 C ATOM 395 CG1 VAL A 89 14.588 62.685 20.815 1.00 28.66 C ATOM 396 CG2 VAL A 89 13.715 65.003 21.029 1.00 28.18 C ATOM 397 N VAL A 90 17.575 63.301 22.999 1.00 26.83 N ATOM 398 CA VAL A 90 18.628 62.372 23.421 1.00 26.02 C ATOM 399 C VAL A 90 18.538 62.091 24.927 1.00 25.41 C ATOM 400 O VAL A 90 18.570 60.938 25.346 1.00 25.21 O ATOM 401 CB VAL A 90 20.040 62.889 23.007 1.00 25.34 C ATOM 402 CG1 VAL A 90 21.162 62.101 23.665 1.00 24.76 C ATOM 403 CG2 VAL A 90 20.194 62.806 21.498 1.00 26.10 C ATOM 404 N GLY A 91 18.420 63.145 25.725 1.00 25.92 N ATOM 405 CA GLY A 91 18.340 63.024 27.182 1.00 26.60 C ATOM 406 C GLY A 91 17.116 62.287 27.708 1.00 27.39 C ATOM 407 O GLY A 91 17.234 61.521 28.661 1.00 27.82 O ATOM 408 N LEU A 92 15.955 62.508 27.082 1.00 28.10 N ATOM 409 CA LEU A 92 14.684 61.924 27.534 1.00 29.18 C ATOM 410 C LEU A 92 14.408 60.531 26.970 1.00 30.68 C ATOM 411 O LEU A 92 13.909 59.666 27.687 1.00 32.24 O ATOM 412 CB LEU A 92 13.502 62.826 27.149 1.00 29.33 C ATOM 413 CG LEU A 92 13.506 64.284 27.634 1.00 29.66 C ATOM 414 CD1 LEU A 92 12.482 65.087 26.847 1.00 29.38 C ATOM 415 CD2 LEU A 92 13.257 64.404 29.132 1.00 29.56 C ATOM 416 N LEU A 93 14.680 60.328 25.681 1.00 31.33 N ATOM 417 CA LEU A 93 14.290 59.089 24.997 1.00 31.56 C ATOM 418 C LEU A 93 15.476 58.171 24.695 1.00 31.93 C ATOM 419 O LEU A 93 15.428 56.986 25.020 1.00 35.31 O ATOM 420 CB LEU A 93 13.508 59.409 23.726 1.00 31.52 C ATOM 421 CG LEU A 93 12.305 60.352 23.895 1.00 32.26 C ATOM 422 CD1 LEU A 93 11.573 60.534 22.576 1.00 32.82 C ATOM 423 CD2 LEU A 93 11.328 59.859 24.949 1.00 32.76 C ATOM 424 N VAL A 94 16.551 58.711 24.128 1.00 30.19 N ATOM 425 CA VAL A 94 17.677 57.883 23.697 1.00 28.95 C ATOM 426 C VAL A 94 18.500 57.372 24.881 1.00 28.74 C ATOM 427 O VAL A 94 18.677 56.164 25.018 1.00 29.25 O ATOM 428 CB VAL A 94 18.581 58.606 22.677 1.00 28.54 C ATOM 429 CG1 VAL A 94 19.745 57.716 22.253 1.00 28.48 C ATOM 430 CG2 VAL A 94 17.769 59.010 21.455 1.00 28.61 C ATOM 431 N VAL A 95 19.000 58.264 25.730 1.00 28.63 N ATOM 432 CA VAL A 95 19.903 57.841 26.815 1.00 29.50 C ATOM 433 C VAL A 95 19.252 56.900 27.853 1.00 30.46 C ATOM 434 O VAL A 95 19.898 55.939 28.273 1.00 31.24 O ATOM 435 CB VAL A 95 20.625 59.049 27.476 1.00 29.28 C ATOM 436 CG1 VAL A 95 21.330 58.666 28.777 1.00 29.09 C ATOM 437 CG2 VAL A 95 21.641 59.633 26.505 1.00 29.30 C ATOM 438 N PRO A 96 17.989 57.149 28.260 1.00 32.14 N ATOM 439 CA PRO A 96 17.365 56.230 29.231 1.00 33.48 C ATOM 440 C PRO A 96 17.178 54.795 28.734 1.00 35.13 C ATOM 441 O PRO A 96 17.458 53.859 29.479 1.00 36.36 O ATOM 442 CB PRO A 96 16.019 56.905 29.526 1.00 33.09 C ATOM 443 CG PRO A 96 16.326 58.354 29.362 1.00 32.77 C ATOM 444 CD PRO A 96 17.191 58.382 28.125 1.00 32.39 C ATOM 445 N PHE A 97 16.715 54.626 27.496 1.00 36.90 N ATOM 446 CA PHE A 97 16.682 53.300 26.851 1.00 37.35 C ATOM 447 C PHE A 97 18.084 52.688 26.720 1.00 36.71 C ATOM 448 O PHE A 97 18.264 51.482 26.910 1.00 37.94 O ATOM 449 CB PHE A 97 16.061 53.379 25.444 1.00 39.23 C ATOM 450 CG PHE A 97 14.550 53.371 25.411 1.00 40.55 C ATOM 451 CD1 PHE A 97 13.817 52.407 26.099 1.00 41.18 C ATOM 452 CD2 PHE A 97 13.855 54.296 24.628 1.00 41.44 C ATOM 453 CE1 PHE A 97 12.428 52.391 26.042 1.00 41.72 C ATOM 454 CE2 PHE A 97 12.467 54.283 24.565 1.00 41.57 C ATOM 455 CZ PHE A 97 11.754 53.324 25.266 1.00 41.79 C ATOM 456 N GLY A 98 19.061 53.515 26.360 1.00 35.58 N ATOM 457 CA GLY A 98 20.446 53.077 26.222 1.00 35.60 C ATOM 458 C GLY A 98 21.078 52.639 27.532 1.00 35.83 C ATOM 459 O GLY A 98 21.778 51.631 27.575 1.00 35.67 O ATOM 460 N ALA A 99 20.833 53.402 28.597 1.00 36.05 N ATOM 461 CA ALA A 99 21.336 53.074 29.942 1.00 35.88 C ATOM 462 C ALA A 99 20.921 51.675 30.387 1.00 35.84 C ATOM 463 O ALA A 99 21.752 50.907 30.869 1.00 36.47 O ATOM 464 CB ALA A 99 20.858 54.102 30.958 1.00 36.05 C ATOM 465 N THR A 100 19.642 51.350 30.199 1.00 35.59 N ATOM 466 CA THR A 100 19.112 50.028 30.540 1.00 35.21 C ATOM 467 C THR A 100 19.763 48.900 29.724 1.00 35.47 C ATOM 468 O THR A 100 19.911 47.796 30.224 1.00 34.74 O ATOM 469 CB THR A 100 17.577 49.948 30.375 1.00 35.14 C ATOM 470 OG1 THR A 100 17.208 50.178 29.008 1.00 34.42 O ATOM 471 CG2 THR A 100 16.876 50.955 31.292 1.00 34.59 C ATOM 472 N LEU A 101 20.137 49.182 28.477 1.00 37.00 N ATOM 473 CA LEU A 101 20.850 48.215 27.633 1.00 39.65 C ATOM 474 C LEU A 101 22.285 47.980 28.119 1.00 42.06 C ATOM 475 O LEU A 101 22.762 46.840 28.142 1.00 41.58 O ATOM 476 CB LEU A 101 20.857 48.683 26.172 1.00 39.74 C ATOM 477 CG LEU A 101 21.508 47.794 25.110 1.00 39.64 C ATOM 478 CD1 LEU A 101 21.063 46.341 25.203 1.00 39.76 C ATOM 479 CD2 LEU A 101 21.194 48.346 23.731 1.00 39.97 C ATOM 480 N VAL A 102 22.959 49.059 28.509 1.00 44.99 N ATOM 481 CA VAL A 102 24.314 48.984 29.054 1.00 48.27 C ATOM 482 C VAL A 102 24.326 48.238 30.400 1.00 50.79 C ATOM 483 O VAL A 102 25.115 47.308 30.575 1.00 52.12 O ATOM 484 CB VAL A 102 24.953 50.397 29.186 1.00 49.41 C ATOM 485 CG1 VAL A 102 26.260 50.360 29.982 1.00 49.67 C ATOM 486 CG2 VAL A 102 25.200 50.996 27.805 1.00 48.17 C ATOM 487 N VAL A 103 23.450 48.625 31.330 1.00 51.94 N ATOM 488 CA VAL A 103 23.478 48.044 32.683 1.00 54.28 C ATOM 489 C VAL A 103 22.987 46.592 32.736 1.00 54.32 C ATOM 490 O VAL A 103 23.614 45.765 33.393 1.00 56.57 O ATOM 491 CB VAL A 103 22.747 48.907 33.752 1.00 55.48 C ATOM 492 CG1 VAL A 103 23.320 50.320 33.788 1.00 56.20 C ATOM 493 CG2 VAL A 103 21.236 48.926 33.549 1.00 57.06 C ATOM 494 N ARG A 104 21.889 46.272 32.049 1.00 53.94 N ATOM 495 CA ARG A 104 21.365 44.891 32.040 1.00 52.90 C ATOM 496 C ARG A 104 22.065 43.982 31.028 1.00 48.13 C ATOM 497 O ARG A 104 22.068 42.768 31.201 1.00 45.40 O ATOM 498 CB ARG A 104 19.847 44.864 31.808 1.00 55.93 C ATOM 499 CG ARG A 104 19.035 45.435 32.962 1.00 60.42 C ATOM 500 CD ARG A 104 18.926 44.456 34.126 1.00 64.64 C ATOM 501 NE ARG A 104 18.707 45.156 35.400 1.00 70.46 N ATOM 502 CZ ARG A 104 17.638 45.047 36.199 1.00 74.22 C ATOM 503 NH1 ARG A 104 16.615 44.240 35.911 1.00 75.05 N ATOM 504 NH2 ARG A 104 17.595 45.760 37.326 1.00 75.84 N ATOM 505 N GLY A 105 22.647 44.562 29.978 1.00 45.86 N ATOM 506 CA GLY A 105 23.307 43.786 28.922 1.00 43.24 C ATOM 507 C GLY A 105 22.368 43.126 27.919 1.00 41.26 C ATOM 508 O GLY A 105 22.804 42.293 27.128 1.00 41.40 O ATOM 509 N THR A 106 21.087 43.499 27.943 1.00 39.20 N ATOM 510 CA THR A 106 20.084 43.001 26.991 1.00 36.75 C ATOM 511 C THR A 106 19.006 44.065 26.792 1.00 33.65 C ATOM 512 O THR A 106 18.900 44.997 27.592 1.00 34.55 O ATOM 513 CB THR A 106 19.442 41.670 27.461 1.00 36.98 C ATOM 514 OG1 THR A 106 18.375 41.299 26.578 1.00 36.87 O ATOM 515 CG2 THR A 106 18.891 41.778 28.882 1.00 37.89 C ATOM 516 N TRP A 107 18.220 43.920 25.729 1.00 30.25 N ATOM 517 CA TRP A 107 17.139 44.854 25.416 1.00 28.39 C ATOM 518 C TRP A 107 15.817 44.358 26.026 1.00 28.22 C ATOM 519 O TRP A 107 15.344 43.273 25.696 1.00 27.40 O ATOM 520 CB TRP A 107 17.016 45.036 23.896 1.00 26.92 C ATOM 521 CG TRP A 107 15.982 46.055 23.480 1.00 24.98 C ATOM 522 CD1 TRP A 107 14.759 45.798 22.953 1.00 24.63 C ATOM 523 CD2 TRP A 107 16.094 47.479 23.557 1.00 23.90 C ATOM 524 NE1 TRP A 107 14.093 46.968 22.700 1.00 24.36 N ATOM 525 CE2 TRP A 107 14.891 48.019 23.057 1.00 23.78 C ATOM 526 CE3 TRP A 107 17.096 48.355 23.990 1.00 23.78 C ATOM 527 CZ2 TRP A 107 14.653 49.397 22.985 1.00 23.62 C ATOM 528 CZ3 TRP A 107 16.862 49.738 23.912 1.00 23.37 C ATOM 529 CH2 TRP A 107 15.649 50.237 23.413 1.00 23.59 C ATOM 530 N LEU A 108 15.234 45.168 26.907 1.00 28.26 N ATOM 531 CA LEU A 108 14.026 44.804 27.651 1.00 28.71 C ATOM 532 C LEU A 108 12.720 45.239 26.976 1.00 28.43 C ATOM 533 O LEU A 108 11.654 44.730 27.324 1.00 28.94 O ATOM 534 CB LEU A 108 14.066 45.437 29.045 1.00 29.51 C ATOM 535 CG LEU A 108 15.328 45.246 29.890 1.00 30.30 C ATOM 536 CD1 LEU A 108 15.261 46.130 31.124 1.00 30.06 C ATOM 537 CD2 LEU A 108 15.505 43.785 30.271 1.00 30.88 C ATOM 538 N TRP A 109 12.792 46.155 26.012 1.00 27.35 N ATOM 539 CA TRP A 109 11.607 46.910 25.578 1.00 26.68 C ATOM 540 C TRP A 109 10.922 46.387 24.309 1.00 26.11 C ATOM 541 O TRP A 109 10.027 47.044 23.777 1.00 25.09 O ATOM 542 CB TRP A 109 11.968 48.397 25.469 1.00 26.80 C ATOM 543 CG TRP A 109 12.645 48.846 26.709 1.00 27.28 C ATOM 544 CD1 TRP A 109 13.967 49.140 26.863 1.00 27.66 C ATOM 545 CD2 TRP A 109 12.055 48.955 28.008 1.00 27.63 C ATOM 546 NE1 TRP A 109 14.230 49.472 28.172 1.00 27.40 N ATOM 547 CE2 TRP A 109 13.073 49.360 28.897 1.00 28.09 C ATOM 548 CE3 TRP A 109 10.758 48.764 28.507 1.00 28.06 C ATOM 549 CZ2 TRP A 109 12.831 49.584 30.263 1.00 29.20 C ATOM 550 CZ3 TRP A 109 10.518 48.980 29.865 1.00 27.98 C ATOM 551 CH2 TRP A 109 11.548 49.387 30.724 1.00 28.53 C ATOM 552 N GLY A 110 11.299 45.193 23.855 1.00 25.54 N ATOM 553 CA GLY A 110 10.662 44.583 22.697 1.00 25.27 C ATOM 554 C GLY A 110 11.153 45.147 21.376 1.00 25.30 C ATOM 555 O GLY A 110 11.878 46.141 21.330 1.00 25.48 O ATOM 556 N SER A 111 10.730 44.504 20.297 1.00 25.22 N ATOM 557 CA SER A 111 11.279 44.757 18.972 1.00 25.76 C ATOM 558 C SER A 111 10.826 46.084 18.371 1.00 26.35 C ATOM 559 O SER A 111 11.601 46.723 17.669 1.00 27.08 O ATOM 560 CB SER A 111 10.946 43.603 18.030 1.00 25.72 C ATOM 561 OG SER A 111 9.548 43.419 17.952 1.00 27.21 O ATOM 562 N PHE A 112 9.592 46.507 18.640 1.00 27.26 N ATOM 563 CA PHE A 112 9.116 47.795 18.118 1.00 28.03 C ATOM 564 C PHE A 112 9.878 48.986 18.703 1.00 27.73 C ATOM 565 O PHE A 112 10.298 49.866 17.966 1.00 28.01 O ATOM 566 CB PHE A 112 7.619 48.010 18.346 1.00 28.45 C ATOM 567 CG PHE A 112 7.170 49.411 18.009 1.00 29.34 C ATOM 568 CD1 PHE A 112 7.294 49.894 16.711 1.00 29.66 C ATOM 569 CD2 PHE A 112 6.678 50.265 18.989 1.00 29.91 C ATOM 570 CE1 PHE A 112 6.911 51.186 16.388 1.00 29.60 C ATOM 571 CE2 PHE A 112 6.294 51.561 18.669 1.00 30.28 C ATOM 572 CZ PHE A 112 6.415 52.021 17.369 1.00 29.82 C ATOM 573 N LEU A 113 10.026 49.018 20.022 1.00 27.62 N ATOM 574 CA LEU A 113 10.725 50.114 20.692 1.00 27.58 C ATOM 575 C LEU A 113 12.223 50.121 20.415 1.00 27.05 C ATOM 576 O LEU A 113 12.847 51.169 20.504 1.00 26.00 O ATOM 577 CB LEU A 113 10.481 50.078 22.203 1.00 28.06 C ATOM 578 CG LEU A 113 9.045 50.413 22.607 1.00 29.62 C ATOM 579 CD1 LEU A 113 8.812 50.084 24.068 1.00 30.25 C ATOM 580 CD2 LEU A 113 8.722 51.884 22.340 1.00 30.12 C ATOM 581 N CYS A 114 12.799 48.957 20.117 1.00 27.47 N ATOM 582 CA CYS A 114 14.167 48.882 19.600 1.00 27.54 C ATOM 583 C CYS A 114 14.280 49.681 18.314 1.00 27.50 C ATOM 584 O CYS A 114 15.212 50.458 18.162 1.00 26.77 O ATOM 585 CB CYS A 114 14.582 47.427 19.337 1.00 27.69 C ATOM 586 SG CYS A 114 16.172 47.224 18.493 1.00 27.85 S ATOM 587 N GLU A 115 13.324 49.480 17.406 1.00 28.72 N ATOM 588 CA GLU A 115 13.307 50.163 16.108 1.00 30.16 C ATOM 589 C GLU A 115 13.025 51.660 16.222 1.00 28.62 C ATOM 590 O GLU A 115 13.642 52.460 15.518 1.00 28.69 O ATOM 591 CB GLU A 115 12.288 49.517 15.165 1.00 33.35 C ATOM 592 CG GLU A 115 12.648 48.099 14.749 1.00 37.55 C ATOM 593 CD GLU A 115 11.684 47.524 13.723 1.00 42.27 C ATOM 594 OE1 GLU A 115 10.503 47.269 14.075 1.00 44.88 O ATOM 595 OE2 GLU A 115 12.112 47.321 12.561 1.00 45.87 O ATOM 596 N LEU A 116 12.091 52.033 17.093 1.00 26.61 N ATOM 597 CA LEU A 116 11.785 53.435 17.330 1.00 25.94 C ATOM 598 C LEU A 116 12.954 54.147 18.006 1.00 25.22 C ATOM 599 O LEU A 116 13.280 55.278 17.651 1.00 24.21 O ATOM 600 CB LEU A 116 10.528 53.576 18.189 1.00 26.57 C ATOM 601 CG LEU A 116 10.108 55.017 18.519 1.00 27.08 C ATOM 602 CD1 LEU A 116 9.698 55.759 17.251 1.00 27.08 C ATOM 603 CD2 LEU A 116 8.996 55.042 19.552 1.00 26.65 C ATOM 604 N TRP A 117 13.553 53.484 18.995 1.00 24.88 N ATOM 605 CA TRP A 117 14.726 54.001 19.699 1.00 25.07 C ATOM 606 C TRP A 117 15.854 54.284 18.719 1.00 24.69 C ATOM 607 O TRP A 117 16.423 55.376 18.726 1.00 24.51 O ATOM 608 CB TRP A 117 15.192 53.008 20.771 1.00 25.37 C ATOM 609 CG TRP A 117 16.461 53.378 21.485 1.00 25.89 C ATOM 610 CD1 TRP A 117 16.674 54.471 22.287 1.00 26.60 C ATOM 611 CD2 TRP A 117 17.688 52.635 21.486 1.00 25.46 C ATOM 612 NE1 TRP A 117 17.965 54.455 22.776 1.00 26.65 N ATOM 613 CE2 TRP A 117 18.607 53.342 22.298 1.00 25.81 C ATOM 614 CE3 TRP A 117 18.100 51.440 20.882 1.00 25.22 C ATOM 615 CZ2 TRP A 117 19.914 52.895 22.514 1.00 25.14 C ATOM 616 CZ3 TRP A 117 19.399 50.993 21.102 1.00 24.80 C ATOM 617 CH2 TRP A 117 20.287 51.718 21.919 1.00 24.96 C ATOM 618 N THR A 118 16.152 53.305 17.871 1.00 24.14 N ATOM 619 CA THR A 118 17.183 53.458 16.850 1.00 24.52 C ATOM 620 C THR A 118 16.878 54.614 15.886 1.00 24.63 C ATOM 621 O THR A 118 17.776 55.389 15.568 1.00 25.42 O ATOM 622 CB THR A 118 17.404 52.154 16.063 1.00 24.55 C ATOM 623 OG1 THR A 118 17.582 51.067 16.979 1.00 25.03 O ATOM 624 CG2 THR A 118 18.636 52.253 15.199 1.00 24.73 C ATOM 625 N SER A 119 15.625 54.743 15.452 1.00 24.21 N ATOM 626 CA SER A 119 15.221 55.817 14.526 1.00 24.26 C ATOM 627 C SER A 119 15.358 57.224 15.123 1.00 24.22 C ATOM 628 O SER A 119 15.739 58.161 14.425 1.00 24.51 O ATOM 629 CB SER A 119 13.780 55.607 14.044 1.00 24.63 C ATOM 630 OG SER A 119 13.652 54.378 13.339 1.00 25.27 O ATOM 631 N LEU A 120 15.036 57.363 16.406 1.00 24.09 N ATOM 632 CA LEU A 120 15.150 58.645 17.112 1.00 24.29 C ATOM 633 C LEU A 120 16.608 59.023 17.369 1.00 23.62 C ATOM 634 O LEU A 120 16.971 60.204 17.316 1.00 23.04 O ATOM 635 CB LEU A 120 14.411 58.595 18.455 1.00 24.67 C ATOM 636 CG LEU A 120 12.891 58.547 18.406 1.00 25.50 C ATOM 637 CD1 LEU A 120 12.352 58.303 19.811 1.00 26.10 C ATOM 638 CD2 LEU A 120 12.314 59.828 17.816 1.00 25.53 C ATOM 639 N ASP A 121 17.412 58.012 17.694 1.00 22.53 N ATOM 640 CA ASP A 121 18.854 58.159 17.861 1.00 22.09 C ATOM 641 C ASP A 121 19.473 58.714 16.566 1.00 22.00 C ATOM 642 O ASP A 121 20.158 59.744 16.574 1.00 22.09 O ATOM 643 CB ASP A 121 19.456 56.791 18.227 1.00 21.87 C ATOM 644 CG ASP A 121 20.901 56.873 18.681 1.00 21.62 C ATOM 645 OD1 ASP A 121 21.538 57.931 18.497 1.00 21.35 O ATOM 646 OD2 ASP A 121 21.406 55.855 19.213 1.00 20.80 O ATOM 647 N VAL A 122 19.184 58.039 15.459 1.00 21.76 N ATOM 648 CA VAL A 122 19.651 58.444 14.122 1.00 21.59 C ATOM 649 C VAL A 122 19.152 59.843 13.716 1.00 21.26 C ATOM 650 O VAL A 122 19.911 60.632 13.140 1.00 20.12 O ATOM 651 CB VAL A 122 19.235 57.398 13.063 1.00 21.22 C ATOM 652 CG1 VAL A 122 19.484 57.899 11.647 1.00 21.39 C ATOM 653 CG2 VAL A 122 19.992 56.091 13.288 1.00 21.60 C ATOM 654 N LEU A 123 17.881 60.123 14.014 1.00 21.52 N ATOM 655 CA LEU A 123 17.247 61.424 13.737 1.00 21.84 C ATOM 656 C LEU A 123 17.951 62.590 14.418 1.00 21.81 C ATOM 657 O LEU A 123 18.231 63.602 13.774 1.00 21.43 O ATOM 658 CB LEU A 123 15.770 61.407 14.175 1.00 22.34 C ATOM 659 CG LEU A 123 15.001 62.739 14.187 1.00 22.59 C ATOM 660 CD1 LEU A 123 14.907 63.314 12.784 1.00 22.79 C ATOM 661 CD2 LEU A 123 13.620 62.551 14.792 1.00 22.79 C ATOM 662 N CYS A 124 18.182 62.451 15.725 1.00 22.20 N ATOM 663 CA CYS A 124 18.836 63.487 16.530 1.00 22.90 C ATOM 664 C CYS A 124 20.236 63.832 16.032 1.00 22.29 C ATOM 665 O CYS A 124 20.607 65.007 15.985 1.00 22.78 O ATOM 666 CB CYS A 124 18.910 63.062 17.997 1.00 24.33 C ATOM 667 SG CYS A 124 17.299 63.007 18.810 1.00 27.35 S ATOM 668 N VAL A 125 21.011 62.818 15.656 1.00 21.43 N ATOM 669 CA VAL A 125 22.343 63.065 15.102 1.00 21.25 C ATOM 670 C VAL A 125 22.240 63.801 13.757 1.00 20.82 C ATOM 671 O VAL A 125 23.003 64.738 13.502 1.00 20.31 O ATOM 672 CB VAL A 125 23.157 61.771 14.930 1.00 21.34 C ATOM 673 CG1 VAL A 125 24.495 62.069 14.265 1.00 21.53 C ATOM 674 CG2 VAL A 125 23.387 61.106 16.284 1.00 21.90 C ATOM 675 N THR A 126 21.290 63.370 12.920 1.00 20.15 N ATOM 676 CA THR A 126 21.108 63.923 11.582 1.00 19.34 C ATOM 677 C THR A 126 20.617 65.362 11.650 1.00 19.67 C ATOM 678 O THR A 126 21.176 66.233 10.991 1.00 20.34 O ATOM 679 CB THR A 126 20.124 63.076 10.757 1.00 18.91 C ATOM 680 OG1 THR A 126 20.568 61.712 10.748 1.00 18.57 O ATOM 681 CG2 THR A 126 20.029 63.589 9.309 1.00 19.24 C ATOM 682 N ALA A 127 19.583 65.609 12.450 1.00 19.66 N ATOM 683 CA ALA A 127 19.033 66.954 12.601 1.00 19.52 C ATOM 684 C ALA A 127 20.062 67.928 13.188 1.00 19.34 C ATOM 685 O ALA A 127 20.105 69.087 12.800 1.00 19.22 O ATOM 686 CB ALA A 127 17.780 66.915 13.464 1.00 19.63 C ATOM 687 N SER A 128 20.879 67.446 14.126 1.00 19.64 N ATOM 688 CA SER A 128 21.951 68.253 14.740 1.00 19.70 C ATOM 689 C SER A 128 23.000 68.706 13.746 1.00 19.19 C ATOM 690 O SER A 128 23.277 69.894 13.644 1.00 19.06 O ATOM 691 CB SER A 128 22.677 67.469 15.831 1.00 19.69 C ATOM 692 OG SER A 128 21.862 67.290 16.967 1.00 19.88 O ATOM 693 N VAL A 129 23.600 67.752 13.042 1.00 19.20 N ATOM 694 CA VAL A 129 24.685 68.080 12.111 1.00 20.05 C ATOM 695 C VAL A 129 24.212 68.911 10.908 1.00 20.40 C ATOM 696 O VAL A 129 24.952 69.774 10.436 1.00 20.53 O ATOM 697 CB VAL A 129 25.516 66.839 11.684 1.00 20.13 C ATOM 698 CG1 VAL A 129 24.715 65.875 10.828 1.00 20.34 C ATOM 699 CG2 VAL A 129 26.791 67.271 10.963 1.00 19.94 C ATOM 700 N TRP A 130 22.988 68.672 10.436 1.00 21.11 N ATOM 701 CA TRP A 130 22.406 69.504 9.371 1.00 21.43 C ATOM 702 C TRP A 130 22.067 70.923 9.848 1.00 21.63 C ATOM 703 O TRP A 130 22.195 71.870 9.075 1.00 22.03 O ATOM 704 CB TRP A 130 21.182 68.823 8.724 1.00 21.88 C ATOM 705 CG TRP A 130 21.589 67.878 7.658 1.00 22.14 C ATOM 706 CD1 TRP A 130 21.614 66.517 7.727 1.00 22.37 C ATOM 707 CD2 TRP A 130 22.094 68.226 6.368 1.00 22.36 C ATOM 708 NE1 TRP A 130 22.092 65.994 6.549 1.00 22.49 N ATOM 709 CE2 TRP A 130 22.394 67.022 5.698 1.00 22.51 C ATOM 710 CE3 TRP A 130 22.325 69.441 5.713 1.00 22.71 C ATOM 711 CZ2 TRP A 130 22.903 66.994 4.400 1.00 22.90 C ATOM 712 CZ3 TRP A 130 22.839 69.415 4.422 1.00 23.17 C ATOM 713 CH2 TRP A 130 23.120 68.199 3.778 1.00 23.11 C ATOM 714 N THR A 131 21.635 71.060 11.103 1.00 21.06 N ATOM 715 CA THR A 131 21.407 72.367 11.720 1.00 20.99 C ATOM 716 C THR A 131 22.714 73.147 11.917 1.00 21.33 C ATOM 717 O THR A 131 22.734 74.369 11.746 1.00 21.73 O ATOM 718 CB THR A 131 20.694 72.233 13.087 1.00 21.14 C ATOM 719 OG1 THR A 131 19.410 71.623 12.904 1.00 21.12 O ATOM 720 CG2 THR A 131 20.514 73.596 13.765 1.00 20.95 C ATOM 721 N LEU A 132 23.796 72.466 12.296 1.00 21.58 N ATOM 722 CA LEU A 132 25.110 73.128 12.355 1.00 21.99 C ATOM 723 C LEU A 132 25.561 73.574 10.959 1.00 22.95 C ATOM 724 O LEU A 132 26.146 74.657 10.796 1.00 23.53 O ATOM 725 CB LEU A 132 26.171 72.239 12.999 1.00 21.28 C ATOM 726 CG LEU A 132 25.951 71.892 14.473 1.00 21.39 C ATOM 727 CD1 LEU A 132 26.881 70.768 14.903 1.00 21.24 C ATOM 728 CD2 LEU A 132 26.120 73.103 15.375 1.00 21.49 C ATOM 729 N CYS A 133 25.271 72.751 9.959 1.00 23.23 N ATOM 730 CA CYS A 133 25.523 73.124 8.575 1.00 25.08 C ATOM 731 C CYS A 133 24.700 74.349 8.108 1.00 24.58 C ATOM 732 O CYS A 133 25.230 75.209 7.401 1.00 24.68 O ATOM 733 CB CYS A 133 25.279 71.933 7.666 1.00 26.56 C ATOM 734 SG CYS A 133 25.700 72.309 5.972 1.00 31.92 S ATOM 735 N VAL A 134 23.429 74.430 8.511 1.00 23.77 N ATOM 736 CA VAL A 134 22.594 75.614 8.256 1.00 24.11 C ATOM 737 C VAL A 134 23.143 76.867 8.959 1.00 24.22 C ATOM 738 O VAL A 134 23.193 77.933 8.355 1.00 24.13 O ATOM 739 CB VAL A 134 21.113 75.387 8.677 1.00 24.51 C ATOM 740 CG1 VAL A 134 20.302 76.683 8.628 1.00 24.38 C ATOM 741 CG2 VAL A 134 20.452 74.347 7.782 1.00 24.48 C ATOM 742 N ILE A 135 23.536 76.730 10.227 1.00 24.88 N ATOM 743 CA ILE A 135 24.138 77.832 11.002 1.00 24.38 C ATOM 744 C ILE A 135 25.397 78.392 10.333 1.00 23.87 C ATOM 745 O ILE A 135 25.568 79.607 10.267 1.00 22.72 O ATOM 746 CB ILE A 135 24.448 77.405 12.463 1.00 24.82 C ATOM 747 CG1 ILE A 135 23.141 77.276 13.251 1.00 24.80 C ATOM 748 CG2 ILE A 135 25.374 78.409 13.166 1.00 25.05 C ATOM 749 CD1 ILE A 135 23.275 76.546 14.572 1.00 24.82 C ATOM 750 N ALA A 136 26.270 77.514 9.846 1.00 24.29 N ATOM 751 CA ALA A 136 27.498 77.950 9.163 1.00 24.73 C ATOM 752 C ALA A 136 27.168 78.763 7.922 1.00 25.75 C ATOM 753 O ALA A 136 27.727 79.842 7.718 1.00 25.76 O ATOM 754 CB ALA A 136 28.370 76.761 8.792 1.00 24.45 C ATOM 755 N ILE A 137 26.242 78.243 7.113 1.00 26.74 N ATOM 756 CA ILE A 137 25.824 78.892 5.861 1.00 27.22 C ATOM 757 C ILE A 137 25.119 80.228 6.120 1.00 26.91 C ATOM 758 O ILE A 137 25.400 81.216 5.449 1.00 26.88 O ATOM 759 CB ILE A 137 24.929 77.945 5.017 1.00 27.89 C ATOM 760 CG1 ILE A 137 25.765 76.770 4.490 1.00 28.20 C ATOM 761 CG2 ILE A 137 24.274 78.677 3.845 1.00 27.90 C ATOM 762 CD1 ILE A 137 24.945 75.588 4.006 1.00 28.36 C ATOM 763 N ASP A 138 24.198 80.223 7.080 1.00 27.83 N ATOM 764 CA ASP A 138 23.461 81.406 7.521 1.00 28.60 C ATOM 765 C ASP A 138 24.420 82.545 7.876 1.00 30.32 C ATOM 766 O ASP A 138 24.313 83.653 7.341 1.00 31.25 O ATOM 767 CB ASP A 138 22.611 81.023 8.738 1.00 28.85 C ATOM 768 CG ASP A 138 21.838 82.195 9.324 1.00 29.69 C ATOM 769 OD1 ASP A 138 20.830 82.613 8.724 1.00 31.50 O ATOM 770 OD2 ASP A 138 22.204 82.671 10.415 1.00 29.12 O ATOM 771 N ARG A 139 25.375 82.239 8.757 1.00 31.13 N ATOM 772 CA ARG A 139 26.342 83.218 9.250 1.00 30.30 C ATOM 773 C ARG A 139 27.276 83.722 8.163 1.00 30.52 C ATOM 774 O ARG A 139 27.604 84.902 8.155 1.00 30.58 O ATOM 775 CB ARG A 139 27.159 82.650 10.421 1.00 30.03 C ATOM 776 CG ARG A 139 26.383 82.449 11.718 1.00 30.34 C ATOM 777 CD ARG A 139 25.737 83.734 12.209 1.00 30.95 C ATOM 778 NE ARG A 139 24.371 83.924 11.700 1.00 31.84 N ATOM 779 CZ ARG A 139 23.695 85.078 11.706 1.00 33.09 C ATOM 780 NH1 ARG A 139 24.231 86.183 12.177 1.00 33.38 N ATOM 781 NH2 ARG A 139 22.457 85.137 11.227 1.00 34.27 N ATOM 782 N TYR A 140 27.705 82.841 7.261 1.00 31.83 N ATOM 783 CA TYR A 140 28.477 83.262 6.080 1.00 33.56 C ATOM 784 C TYR A 140 27.735 84.321 5.264 1.00 34.02 C ATOM 785 O TYR A 140 28.310 85.352 4.925 1.00 32.59 O ATOM 786 CB TYR A 140 28.820 82.081 5.171 1.00 34.17 C ATOM 787 CG TYR A 140 29.707 82.497 4.021 1.00 37.34 C ATOM 788 CD1 TYR A 140 31.073 82.724 4.216 1.00 39.14 C ATOM 789 CD2 TYR A 140 29.179 82.705 2.741 1.00 38.97 C ATOM 790 CE1 TYR A 140 31.891 83.124 3.164 1.00 40.84 C ATOM 791 CE2 TYR A 140 29.986 83.107 1.686 1.00 39.67 C ATOM 792 CZ TYR A 140 31.338 83.315 1.897 1.00 41.24 C ATOM 793 OH TYR A 140 32.139 83.712 0.848 1.00 43.50 O ATOM 794 N LEU A 141 26.461 84.063 4.972 1.00 34.93 N ATOM 795 CA LEU A 141 25.639 85.016 4.229 1.00 37.13 C ATOM 796 C LEU A 141 25.381 86.287 5.035 1.00 37.56 C ATOM 797 O LEU A 141 25.342 87.383 4.469 1.00 38.81 O ATOM 798 CB LEU A 141 24.316 84.375 3.786 1.00 37.06 C ATOM 799 CG LEU A 141 24.466 83.210 2.803 1.00 38.03 C ATOM 800 CD1 LEU A 141 23.132 82.512 2.586 1.00 39.08 C ATOM 801 CD2 LEU A 141 25.056 83.669 1.476 1.00 38.29 C ATOM 802 N ALA A 142 25.222 86.132 6.348 1.00 37.50 N ATOM 803 CA ALA A 142 25.028 87.266 7.244 1.00 38.34 C ATOM 804 C ALA A 142 26.224 88.240 7.270 1.00 39.99 C ATOM 805 O ALA A 142 26.022 89.451 7.190 1.00 39.76 O ATOM 806 CB ALA A 142 24.699 86.776 8.644 1.00 38.01 C ATOM 807 N ILE A 143 27.453 87.727 7.378 1.00 41.31 N ATOM 808 CA ILE A 143 28.651 88.606 7.355 1.00 43.07 C ATOM 809 C ILE A 143 28.998 89.171 5.974 1.00 42.81 C ATOM 810 O ILE A 143 29.435 90.317 5.884 1.00 42.85 O ATOM 811 CB ILE A 143 29.936 87.966 7.965 1.00 45.19 C ATOM 812 CG1 ILE A 143 30.357 86.681 7.236 1.00 46.04 C ATOM 813 CG2 ILE A 143 29.765 87.760 9.464 1.00 46.29 C ATOM 814 CD1 ILE A 143 31.603 86.051 7.815 1.00 48.20 C ATOM 815 N THR A 144 28.817 88.373 4.918 1.00 42.50 N ATOM 816 CA THR A 144 29.173 88.785 3.550 1.00 42.09 C ATOM 817 C THR A 144 28.122 89.678 2.882 1.00 43.41 C ATOM 818 O THR A 144 28.466 90.472 2.007 1.00 44.44 O ATOM 819 CB THR A 144 29.445 87.577 2.628 1.00 40.52 C ATOM 820 OG1 THR A 144 28.320 86.692 2.637 1.00 38.74 O ATOM 821 CG2 THR A 144 30.688 86.828 3.077 1.00 40.49 C ATOM 822 N SER A 145 26.856 89.527 3.271 1.00 43.41 N ATOM 823 CA SER A 145 25.780 90.402 2.804 1.00 45.06 C ATOM 824 C SER A 145 24.860 90.778 3.968 1.00 44.98 C ATOM 825 O SER A 145 23.700 90.364 4.001 1.00 43.96 O ATOM 826 CB SER A 145 24.979 89.721 1.689 1.00 46.33 C ATOM 827 OG SER A 145 25.795 89.461 0.562 1.00 50.75 O ATOM 828 N PRO A 146 25.367 91.582 4.926 1.00 45.89 N ATOM 829 CA PRO A 146 24.532 91.972 6.077 1.00 47.01 C ATOM 830 C PRO A 146 23.301 92.790 5.692 1.00 48.55 C ATOM 831 O PRO A 146 22.279 92.734 6.373 1.00 46.82 O ATOM 832 CB PRO A 146 25.479 92.818 6.948 1.00 46.44 C ATOM 833 CG PRO A 146 26.830 92.737 6.326 1.00 46.63 C ATOM 834 CD PRO A 146 26.646 92.315 4.902 1.00 46.48 C ATOM 835 N PHE A 147 23.412 93.516 4.585 1.00 52.79 N ATOM 836 CA PHE A 147 22.378 94.427 4.115 1.00 55.70 C ATOM 837 C PHE A 147 21.197 93.613 3.581 1.00 53.84 C ATOM 838 O PHE A 147 20.062 93.769 4.044 1.00 50.74 O ATOM 839 CB PHE A 147 22.964 95.361 3.040 1.00 59.04 C ATOM 840 CG PHE A 147 24.232 96.071 3.475 1.00 62.41 C ATOM 841 CD1 PHE A 147 24.166 97.200 4.280 1.00 64.21 C ATOM 842 CD2 PHE A 147 25.492 95.596 3.100 1.00 63.23 C ATOM 843 CE1 PHE A 147 25.320 97.856 4.696 1.00 65.00 C ATOM 844 CE2 PHE A 147 26.652 96.244 3.515 1.00 64.47 C ATOM 845 CZ PHE A 147 26.566 97.379 4.313 1.00 65.27 C ATOM 846 N ARG A 148 21.487 92.721 2.636 1.00 53.71 N ATOM 847 CA ARG A 148 20.487 91.803 2.092 1.00 54.54 C ATOM 848 C ARG A 148 19.925 90.883 3.167 1.00 54.94 C ATOM 849 O ARG A 148 18.701 90.764 3.310 1.00 54.60 O ATOM 850 CB ARG A 148 21.094 90.954 0.979 1.00 56.63 C ATOM 851 CG ARG A 148 20.153 89.902 0.399 1.00 59.88 C ATOM 852 CD ARG A 148 20.754 89.199 -0.807 1.00 62.80 C ATOM 853 NE ARG A 148 21.257 90.154 -1.793 1.00 65.39 N ATOM 854 CZ ARG A 148 20.499 90.894 -2.605 1.00 69.08 C ATOM 855 NH1 ARG A 148 19.165 90.817 -2.580 1.00 70.01 N ATOM 856 NH2 ARG A 148 21.085 91.734 -3.458 1.00 70.29 N ATOM 857 N TYR A 149 20.825 90.231 3.907 1.00 53.28 N ATOM 858 CA TYR A 149 20.443 89.254 4.929 1.00 50.47 C ATOM 859 C TYR A 149 19.369 89.794 5.864 1.00 54.57 C ATOM 860 O TYR A 149 18.380 89.117 6.135 1.00 55.08 O ATOM 861 CB TYR A 149 21.656 88.802 5.761 1.00 46.98 C ATOM 862 CG TYR A 149 21.288 87.767 6.803 1.00 43.48 C ATOM 863 CD1 TYR A 149 20.836 88.149 8.069 1.00 41.59 C ATOM 864 CD2 TYR A 149 21.347 86.408 6.512 1.00 41.38 C ATOM 865 CE1 TYR A 149 20.465 87.211 9.016 1.00 39.76 C ATOM 866 CE2 TYR A 149 20.987 85.462 7.457 1.00 40.41 C ATOM 867 CZ TYR A 149 20.542 85.869 8.711 1.00 39.93 C ATOM 868 OH TYR A 149 20.173 84.953 9.676 1.00 38.43 O ATOM 869 N GLN A 150 19.575 91.014 6.349 1.00 60.40 N ATOM 870 CA GLN A 150 18.716 91.591 7.384 1.00 65.23 C ATOM 871 C GLN A 150 17.356 92.042 6.833 1.00 64.12 C ATOM 872 O GLN A 150 16.358 91.996 7.555 1.00 62.77 O ATOM 873 CB GLN A 150 19.445 92.741 8.093 1.00 69.37 C ATOM 874 CG GLN A 150 19.041 92.950 9.547 1.00 75.15 C ATOM 875 CD GLN A 150 20.095 93.697 10.351 1.00 80.33 C ATOM 876 OE1 GLN A 150 21.007 94.308 9.789 1.00 84.60 O ATOM 877 NE2 GLN A 150 19.976 93.651 11.677 1.00 83.43 N ATOM 878 N SER A 151 17.314 92.459 5.566 1.00 64.27 N ATOM 879 CA SER A 151 16.041 92.796 4.910 1.00 65.70 C ATOM 880 C SER A 151 15.235 91.545 4.522 1.00 64.33 C ATOM 881 O SER A 151 14.006 91.593 4.494 1.00 63.98 O ATOM 882 CB SER A 151 16.263 93.697 3.683 1.00 65.74 C ATOM 883 OG SER A 151 16.603 92.951 2.526 1.00 67.63 O ATOM 884 N LEU A 152 15.926 90.435 4.243 1.00 64.80 N ATOM 885 CA LEU A 152 15.296 89.222 3.702 1.00 65.82 C ATOM 886 C LEU A 152 14.974 88.130 4.742 1.00 65.25 C ATOM 887 O LEU A 152 13.914 87.511 4.659 1.00 68.63 O ATOM 888 CB LEU A 152 16.176 88.650 2.584 1.00 66.68 C ATOM 889 CG LEU A 152 15.592 87.592 1.638 1.00 68.28 C ATOM 890 CD1 LEU A 152 14.218 87.973 1.097 1.00 68.10 C ATOM 891 CD2 LEU A 152 16.562 87.339 0.489 1.00 68.10 C ATOM 892 N MET A 153 15.869 87.888 5.704 1.00 63.09 N ATOM 893 CA MET A 153 15.635 86.851 6.727 1.00 60.72 C ATOM 894 C MET A 153 14.754 87.370 7.855 1.00 60.65 C ATOM 895 O MET A 153 14.941 88.489 8.327 1.00 59.18 O ATOM 896 CB MET A 153 16.950 86.303 7.309 1.00 60.32 C ATOM 897 CG MET A 153 17.566 85.160 6.511 1.00 59.52 C ATOM 898 SD MET A 153 16.607 83.627 6.547 1.00 60.92 S ATOM 899 CE MET A 153 16.755 83.139 8.263 1.00 60.30 C ATOM 900 N THR A 154 13.799 86.539 8.272 1.00 62.20 N ATOM 901 CA THR A 154 12.898 86.835 9.388 1.00 63.05 C ATOM 902 C THR A 154 12.815 85.645 10.342 1.00 63.35 C ATOM 903 O THR A 154 13.221 84.529 10.004 1.00 60.95 O ATOM 904 CB THR A 154 11.470 87.160 8.898 1.00 62.56 C ATOM 905 OG1 THR A 154 10.952 86.055 8.147 1.00 62.24 O ATOM 906 CG2 THR A 154 11.464 88.414 8.034 1.00 61.47 C ATOM 907 N ARG A 155 12.276 85.911 11.530 1.00 65.08 N ATOM 908 CA ARG A 155 12.089 84.906 12.583 1.00 66.12 C ATOM 909 C ARG A 155 11.243 83.717 12.109 1.00 65.91 C ATOM 910 O ARG A 155 11.516 82.572 12.474 1.00 66.35 O ATOM 911 CB ARG A 155 11.439 85.557 13.810 1.00 69.13 C ATOM 912 CG ARG A 155 11.579 84.762 15.099 1.00 72.93 C ATOM 913 CD ARG A 155 11.239 85.596 16.333 1.00 74.44 C ATOM 914 NE ARG A 155 12.046 86.815 16.428 1.00 75.06 N ATOM 915 CZ ARG A 155 13.338 86.868 16.762 1.00 76.62 C ATOM 916 NH1 ARG A 155 14.029 85.767 17.057 1.00 77.09 N ATOM 917 NH2 ARG A 155 13.951 88.047 16.804 1.00 78.48 N ATOM 918 N ALA A 156 10.227 84.002 11.295 1.00 65.16 N ATOM 919 CA ALA A 156 9.365 82.970 10.712 1.00 63.61 C ATOM 920 C ALA A 156 10.083 82.124 9.656 1.00 62.51 C ATOM 921 O ALA A 156 9.882 80.908 9.598 1.00 66.60 O ATOM 922 CB ALA A 156 8.113 83.602 10.115 1.00 63.55 C ATOM 923 N ARG A 157 10.907 82.760 8.823 1.00 57.73 N ATOM 924 CA ARG A 157 11.668 82.039 7.796 1.00 56.16 C ATOM 925 C ARG A 157 12.728 81.093 8.389 1.00 54.18 C ATOM 926 O ARG A 157 13.037 80.054 7.795 1.00 52.39 O ATOM 927 CB ARG A 157 12.318 83.022 6.821 1.00 58.16 C ATOM 928 CG ARG A 157 13.031 82.358 5.652 1.00 60.38 C ATOM 929 CD ARG A 157 13.252 83.317 4.496 1.00 62.76 C ATOM 930 NE ARG A 157 14.330 82.871 3.610 1.00 65.45 N ATOM 931 CZ ARG A 157 14.678 83.465 2.467 1.00 68.03 C ATOM 932 NH1 ARG A 157 14.034 84.547 2.026 1.00 69.91 N ATOM 933 NH2 ARG A 157 15.678 82.966 1.748 1.00 68.99 N ATOM 934 N ALA A 158 13.282 81.458 9.547 1.00 51.91 N ATOM 935 CA ALA A 158 14.175 80.574 10.303 1.00 49.23 C ATOM 936 C ALA A 158 13.453 79.300 10.748 1.00 47.28 C ATOM 937 O ALA A 158 13.969 78.200 10.545 1.00 46.63 O ATOM 938 CB ALA A 158 14.760 81.300 11.507 1.00 49.21 C ATOM 939 N LYS A 159 12.264 79.456 11.337 1.00 46.11 N ATOM 940 CA LYS A 159 11.430 78.313 11.766 1.00 46.17 C ATOM 941 C LYS A 159 11.111 77.344 10.621 1.00 43.38 C ATOM 942 O LYS A 159 11.124 76.124 10.807 1.00 43.12 O ATOM 943 CB LYS A 159 10.111 78.790 12.389 1.00 48.53 C ATOM 944 CG LYS A 159 10.227 79.401 13.780 1.00 50.56 C ATOM 945 CD LYS A 159 8.855 79.839 14.288 1.00 52.67 C ATOM 946 CE LYS A 159 8.775 79.886 15.806 1.00 54.64 C ATOM 947 NZ LYS A 159 9.450 81.089 16.362 1.00 57.12 N ATOM 948 N VAL A 160 10.828 77.900 9.446 1.00 41.05 N ATOM 949 CA VAL A 160 10.552 77.110 8.241 1.00 38.99 C ATOM 950 C VAL A 160 11.763 76.264 7.837 1.00 37.41 C ATOM 951 O VAL A 160 11.617 75.082 7.497 1.00 37.67 O ATOM 952 CB VAL A 160 10.097 78.024 7.067 1.00 39.28 C ATOM 953 CG1 VAL A 160 10.106 77.292 5.721 1.00 38.10 C ATOM 954 CG2 VAL A 160 8.710 78.585 7.351 1.00 38.97 C ATOM 955 N ILE A 161 12.949 76.871 7.868 1.00 35.59 N ATOM 956 CA ILE A 161 14.194 76.147 7.573 1.00 34.55 C ATOM 957 C ILE A 161 14.417 75.015 8.585 1.00 33.27 C ATOM 958 O ILE A 161 14.765 73.901 8.200 1.00 31.30 O ATOM 959 CB ILE A 161 15.423 77.087 7.538 1.00 34.42 C ATOM 960 CG1 ILE A 161 15.328 78.042 6.339 1.00 34.54 C ATOM 961 CG2 ILE A 161 16.722 76.282 7.451 1.00 34.44 C ATOM 962 CD1 ILE A 161 16.189 79.283 6.461 1.00 34.53 C ATOM 963 N ILE A 162 14.194 75.313 9.864 1.00 32.35 N ATOM 964 CA ILE A 162 14.319 74.324 10.938 1.00 32.38 C ATOM 965 C ILE A 162 13.363 73.147 10.708 1.00 33.02 C ATOM 966 O ILE A 162 13.760 71.987 10.858 1.00 32.14 O ATOM 967 CB ILE A 162 14.083 74.963 12.334 1.00 32.12 C ATOM 968 CG1 ILE A 162 15.211 75.950 12.660 1.00 32.11 C ATOM 969 CG2 ILE A 162 14.015 73.895 13.423 1.00 32.22 C ATOM 970 CD1 ILE A 162 14.932 76.853 13.840 1.00 32.16 C ATOM 971 N CYS A 163 12.116 73.457 10.340 1.00 33.73 N ATOM 972 CA ACYS A 163 11.103 72.440 10.031 0.50 33.30 C ATOM 973 CA BCYS A 163 11.124 72.420 10.055 0.50 33.55 C ATOM 974 C CYS A 163 11.529 71.559 8.859 1.00 32.73 C ATOM 975 O CYS A 163 11.373 70.343 8.901 1.00 33.89 O ATOM 976 CB ACYS A 163 9.753 73.103 9.717 0.50 33.87 C ATOM 977 CB BCYS A 163 9.730 73.024 9.847 0.50 34.41 C ATOM 978 SG ACYS A 163 8.421 71.960 9.269 0.50 33.57 S ATOM 979 SG BCYS A 163 8.925 73.498 11.395 0.50 34.82 S ATOM 980 N THR A 164 12.056 72.181 7.808 1.00 31.59 N ATOM 981 CA THR A 164 12.540 71.438 6.635 1.00 31.46 C ATOM 982 C THR A 164 13.700 70.491 7.004 1.00 31.34 C ATOM 983 O THR A 164 13.704 69.329 6.589 1.00 33.01 O ATOM 984 CB THR A 164 12.964 72.397 5.506 1.00 32.17 C ATOM 985 OG1 THR A 164 11.891 73.304 5.232 1.00 32.89 O ATOM 986 CG2 THR A 164 13.312 71.646 4.226 1.00 32.42 C ATOM 987 N VAL A 165 14.650 70.980 7.805 1.00 29.67 N ATOM 988 CA VAL A 165 15.721 70.143 8.353 1.00 29.20 C ATOM 989 C VAL A 165 15.150 68.909 9.086 1.00 29.43 C ATOM 990 O VAL A 165 15.477 67.775 8.727 1.00 28.49 O ATOM 991 CB VAL A 165 16.676 70.946 9.281 1.00 29.05 C ATOM 992 CG1 VAL A 165 17.617 70.025 10.059 1.00 28.67 C ATOM 993 CG2 VAL A 165 17.493 71.947 8.471 1.00 29.04 C ATOM 994 N TRP A 166 14.298 69.128 10.088 1.00 29.16 N ATOM 995 CA TRP A 166 13.706 68.009 10.847 1.00 29.86 C ATOM 996 C TRP A 166 12.789 67.096 10.008 1.00 31.32 C ATOM 997 O TRP A 166 12.729 65.890 10.250 1.00 30.97 O ATOM 998 CB TRP A 166 12.950 68.513 12.082 1.00 29.46 C ATOM 999 CG TRP A 166 13.841 68.912 13.239 1.00 29.24 C ATOM 1000 CD1 TRP A 166 14.437 70.123 13.440 1.00 28.98 C ATOM 1001 CD2 TRP A 166 14.211 68.098 14.362 1.00 29.04 C ATOM 1002 NE1 TRP A 166 15.156 70.116 14.611 1.00 28.14 N ATOM 1003 CE2 TRP A 166 15.035 68.886 15.197 1.00 28.71 C ATOM 1004 CE3 TRP A 166 13.928 66.780 14.742 1.00 29.11 C ATOM 1005 CZ2 TRP A 166 15.582 68.396 16.390 1.00 29.53 C ATOM 1006 CZ3 TRP A 166 14.473 66.292 15.932 1.00 29.30 C ATOM 1007 CH2 TRP A 166 15.291 67.098 16.738 1.00 29.23 C ATOM 1008 N ALA A 167 12.085 67.670 9.031 1.00 33.09 N ATOM 1009 CA ALA A 167 11.240 66.895 8.117 1.00 33.21 C ATOM 1010 C ALA A 167 12.072 66.006 7.192 1.00 33.86 C ATOM 1011 O ALA A 167 11.782 64.815 7.075 1.00 35.24 O ATOM 1012 CB ALA A 167 10.336 67.811 7.308 1.00 33.32 C ATOM 1013 N ILE A 168 13.113 66.560 6.561 1.00 34.40 N ATOM 1014 CA ILE A 168 14.015 65.741 5.723 1.00 34.68 C ATOM 1015 C ILE A 168 14.778 64.735 6.594 1.00 33.57 C ATOM 1016 O ILE A 168 14.857 63.558 6.244 1.00 33.99 O ATOM 1017 CB ILE A 168 15.031 66.559 4.888 1.00 35.92 C ATOM 1018 CG1 ILE A 168 14.333 67.559 3.956 1.00 37.08 C ATOM 1019 CG2 ILE A 168 15.877 65.624 4.019 1.00 35.97 C ATOM 1020 CD1 ILE A 168 15.225 68.714 3.546 1.00 37.87 C ATOM 1021 N SER A 169 15.327 65.194 7.721 1.00 32.53 N ATOM 1022 CA SER A 169 16.029 64.306 8.663 1.00 31.36 C ATOM 1023 C SER A 169 15.169 63.106 9.035 1.00 30.90 C ATOM 1024 O SER A 169 15.643 61.982 9.004 1.00 29.74 O ATOM 1025 CB SER A 169 16.455 65.051 9.931 1.00 30.70 C ATOM 1026 OG SER A 169 17.465 65.995 9.639 1.00 30.44 O ATOM 1027 N ALA A 170 13.904 63.355 9.360 1.00 32.26 N ATOM 1028 CA ALA A 170 12.947 62.284 9.675 1.00 34.10 C ATOM 1029 C ALA A 170 12.703 61.335 8.496 1.00 36.17 C ATOM 1030 O ALA A 170 12.653 60.119 8.693 1.00 35.02 O ATOM 1031 CB ALA A 170 11.633 62.871 10.157 1.00 34.39 C ATOM 1032 N LEU A 171 12.568 61.888 7.284 1.00 38.95 N ATOM 1033 CA LEU A 171 12.476 61.077 6.051 1.00 41.26 C ATOM 1034 C LEU A 171 13.658 60.115 5.945 1.00 41.48 C ATOM 1035 O LEU A 171 13.466 58.893 5.980 1.00 41.12 O ATOM 1036 CB LEU A 171 12.395 61.965 4.787 1.00 43.85 C ATOM 1037 CG LEU A 171 12.693 61.344 3.405 1.00 46.14 C ATOM 1038 CD1 LEU A 171 11.556 60.430 2.978 1.00 46.95 C ATOM 1039 CD2 LEU A 171 12.953 62.410 2.345 1.00 47.05 C ATOM 1040 N VAL A 172 14.869 60.674 5.842 1.00 40.87 N ATOM 1041 CA VAL A 172 16.088 59.864 5.676 1.00 40.65 C ATOM 1042 C VAL A 172 16.392 58.946 6.871 1.00 39.47 C ATOM 1043 O VAL A 172 17.066 57.933 6.697 1.00 41.55 O ATOM 1044 CB VAL A 172 17.352 60.710 5.339 1.00 43.09 C ATOM 1045 CG1 VAL A 172 17.144 61.518 4.062 1.00 44.06 C ATOM 1046 CG2 VAL A 172 17.773 61.622 6.492 1.00 44.13 C ATOM 1047 N SER A 173 15.910 59.300 8.066 1.00 37.09 N ATOM 1048 CA SER A 173 16.125 58.499 9.272 1.00 36.04 C ATOM 1049 C SER A 173 15.106 57.376 9.400 1.00 36.99 C ATOM 1050 O SER A 173 15.480 56.216 9.536 1.00 37.83 O ATOM 1051 CB SER A 173 16.064 59.370 10.532 1.00 35.74 C ATOM 1052 OG SER A 173 17.057 60.381 10.516 1.00 34.77 O ATOM 1053 N PHE A 174 13.821 57.720 9.366 1.00 37.39 N ATOM 1054 CA PHE A 174 12.760 56.742 9.657 1.00 38.07 C ATOM 1055 C PHE A 174 12.470 55.788 8.499 1.00 38.99 C ATOM 1056 O PHE A 174 12.263 54.598 8.727 1.00 39.91 O ATOM 1057 CB PHE A 174 11.461 57.426 10.116 1.00 37.65 C ATOM 1058 CG PHE A 174 11.406 57.687 11.594 1.00 37.33 C ATOM 1059 CD1 PHE A 174 11.994 58.822 12.140 1.00 38.18 C ATOM 1060 CD2 PHE A 174 10.763 56.790 12.448 1.00 37.55 C ATOM 1061 CE1 PHE A 174 11.945 59.058 13.512 1.00 38.40 C ATOM 1062 CE2 PHE A 174 10.707 57.020 13.816 1.00 37.21 C ATOM 1063 CZ PHE A 174 11.302 58.154 14.350 1.00 38.08 C ATOM 1064 N LEU A 175 12.453 56.293 7.268 1.00 39.18 N ATOM 1065 CA LEU A 175 12.088 55.457 6.124 1.00 39.36 C ATOM 1066 C LEU A 175 12.959 54.195 6.016 1.00 38.65 C ATOM 1067 O LEU A 175 12.407 53.086 6.021 1.00 35.80 O ATOM 1068 CB LEU A 175 12.076 56.262 4.811 1.00 41.71 C ATOM 1069 CG LEU A 175 11.848 55.517 3.496 1.00 43.17 C ATOM 1070 CD1 LEU A 175 10.471 54.875 3.489 1.00 44.39 C ATOM 1071 CD2 LEU A 175 12.002 56.479 2.329 1.00 44.72 C ATOM 1072 N PRO A 176 14.312 54.348 5.948 1.00 37.51 N ATOM 1073 CA PRO A 176 15.149 53.146 5.803 1.00 35.68 C ATOM 1074 C PRO A 176 15.041 52.143 6.959 1.00 35.12 C ATOM 1075 O PRO A 176 15.159 50.942 6.727 1.00 32.43 O ATOM 1076 CB PRO A 176 16.571 53.717 5.709 1.00 35.82 C ATOM 1077 CG PRO A 176 16.382 55.113 5.237 1.00 36.06 C ATOM 1078 CD PRO A 176 15.149 55.563 5.955 1.00 36.57 C ATOM 1079 N ILE A 177 14.794 52.637 8.174 1.00 36.53 N ATOM 1080 CA ILE A 177 14.645 51.781 9.355 1.00 37.96 C ATOM 1081 C ILE A 177 13.319 51.015 9.287 1.00 40.71 C ATOM 1082 O ILE A 177 13.297 49.803 9.517 1.00 40.82 O ATOM 1083 CB ILE A 177 14.743 52.583 10.677 1.00 38.08 C ATOM 1084 CG1 ILE A 177 16.065 53.365 10.763 1.00 38.10 C ATOM 1085 CG2 ILE A 177 14.594 51.667 11.894 1.00 37.98 C ATOM 1086 CD1 ILE A 177 17.320 52.528 10.791 1.00 38.70 C ATOM 1087 N MET A 178 12.233 51.725 8.968 1.00 44.60 N ATOM 1088 CA MET A 178 10.915 51.114 8.715 1.00 48.06 C ATOM 1089 C MET A 178 10.963 50.023 7.645 1.00 47.53 C ATOM 1090 O MET A 178 10.432 48.932 7.853 1.00 47.59 O ATOM 1091 CB MET A 178 9.892 52.174 8.279 1.00 52.55 C ATOM 1092 CG MET A 178 9.307 53.000 9.412 1.00 56.57 C ATOM 1093 SD MET A 178 8.510 54.518 8.838 1.00 65.25 S ATOM 1094 CE MET A 178 7.376 53.912 7.583 1.00 63.22 C ATOM 1095 N MET A 179 11.610 50.325 6.518 1.00 46.41 N ATOM 1096 CA MET A 179 11.688 49.407 5.368 1.00 46.81 C ATOM 1097 C MET A 179 12.689 48.247 5.498 1.00 45.10 C ATOM 1098 O MET A 179 12.759 47.410 4.598 1.00 45.59 O ATOM 1099 CB MET A 179 12.022 50.194 4.088 1.00 49.57 C ATOM 1100 CG MET A 179 11.002 51.255 3.692 1.00 52.13 C ATOM 1101 SD MET A 179 9.482 50.558 3.025 1.00 54.91 S ATOM 1102 CE MET A 179 8.441 50.492 4.487 1.00 54.53 C ATOM 1103 N HIS A 180 13.460 48.198 6.586 1.00 44.10 N ATOM 1104 CA HIS A 180 14.501 47.171 6.801 1.00 43.80 C ATOM 1105 C HIS A 180 15.628 47.173 5.750 1.00 41.04 C ATOM 1106 O HIS A 180 16.274 46.150 5.528 1.00 41.74 O ATOM 1107 CB HIS A 180 13.888 45.762 6.948 1.00 45.53 C ATOM 1108 CG HIS A 180 13.001 45.609 8.145 1.00 47.74 C ATOM 1109 ND1 HIS A 180 11.928 44.746 8.169 1.00 50.39 N ATOM 1110 CD2 HIS A 180 13.029 46.208 9.360 1.00 48.51 C ATOM 1111 CE1 HIS A 180 11.335 44.815 9.349 1.00 50.16 C ATOM 1112 NE2 HIS A 180 11.982 45.698 10.089 1.00 48.77 N ATOM 1113 N TRP A 181 15.889 48.333 5.148 1.00 38.29 N ATOM 1114 CA TRP A 181 16.994 48.502 4.194 1.00 37.53 C ATOM 1115 C TRP A 181 18.377 48.313 4.835 1.00 35.54 C ATOM 1116 O TRP A 181 19.360 48.039 4.156 1.00 34.94 O ATOM 1117 CB TRP A 181 16.927 49.900 3.562 1.00 39.72 C ATOM 1118 CG TRP A 181 15.767 50.131 2.621 1.00 40.47 C ATOM 1119 CD1 TRP A 181 14.908 49.193 2.110 1.00 41.46 C ATOM 1120 CD2 TRP A 181 15.371 51.383 2.054 1.00 40.86 C ATOM 1121 NE1 TRP A 181 13.996 49.790 1.277 1.00 41.74 N ATOM 1122 CE2 TRP A 181 14.259 51.132 1.219 1.00 42.03 C ATOM 1123 CE3 TRP A 181 15.850 52.692 2.166 1.00 41.48 C ATOM 1124 CZ2 TRP A 181 13.610 52.149 0.503 1.00 43.38 C ATOM 1125 CZ3 TRP A 181 15.205 53.706 1.453 1.00 43.44 C ATOM 1126 CH2 TRP A 181 14.094 53.425 0.634 1.00 43.79 C ATOM 1127 N TRP A 182 18.429 48.485 6.148 1.00 35.05 N ATOM 1128 CA TRP A 182 19.645 48.347 6.954 1.00 34.40 C ATOM 1129 C TRP A 182 20.087 46.915 7.251 1.00 34.72 C ATOM 1130 O TRP A 182 21.255 46.702 7.548 1.00 35.16 O ATOM 1131 CB TRP A 182 19.493 49.111 8.284 1.00 34.78 C ATOM 1132 CG TRP A 182 18.307 48.692 9.107 1.00 34.58 C ATOM 1133 CD1 TRP A 182 17.013 49.071 8.925 1.00 34.55 C ATOM 1134 CD2 TRP A 182 18.310 47.813 10.232 1.00 35.33 C ATOM 1135 NE1 TRP A 182 16.204 48.480 9.857 1.00 35.41 N ATOM 1136 CE2 TRP A 182 16.974 47.703 10.678 1.00 35.28 C ATOM 1137 CE3 TRP A 182 19.310 47.105 10.911 1.00 35.96 C ATOM 1138 CZ2 TRP A 182 16.610 46.917 11.772 1.00 35.61 C ATOM 1139 CZ3 TRP A 182 18.947 46.322 12.011 1.00 36.18 C ATOM 1140 CH2 TRP A 182 17.609 46.237 12.426 1.00 36.11 C ATOM 1141 N ARG A 183 19.190 45.938 7.153 1.00 35.74 N ATOM 1142 CA ARG A 183 19.488 44.592 7.649 1.00 38.25 C ATOM 1143 C ARG A 183 20.606 43.876 6.878 1.00 38.25 C ATOM 1144 O ARG A 183 20.765 44.056 5.668 1.00 37.09 O ATOM 1145 CB ARG A 183 18.221 43.729 7.698 1.00 40.89 C ATOM 1146 CG ARG A 183 17.168 44.298 8.641 1.00 43.19 C ATOM 1147 CD ARG A 183 16.154 43.278 9.134 1.00 44.94 C ATOM 1148 NE ARG A 183 15.390 43.837 10.250 1.00 47.37 N ATOM 1149 CZ ARG A 183 14.549 43.160 11.035 1.00 48.79 C ATOM 1150 NH1 ARG A 183 14.314 41.864 10.842 1.00 49.10 N ATOM 1151 NH2 ARG A 183 13.927 43.799 12.028 1.00 51.05 N ATOM 1152 N ASP A 184 21.388 43.100 7.626 1.00 38.92 N ATOM 1153 CA ASP A 184 22.485 42.291 7.117 1.00 41.04 C ATOM 1154 C ASP A 184 21.983 40.849 7.059 1.00 40.94 C ATOM 1155 O ASP A 184 21.000 40.515 7.709 1.00 39.76 O ATOM 1156 CB ASP A 184 23.688 42.421 8.061 1.00 43.37 C ATOM 1157 CG ASP A 184 24.972 41.874 7.466 1.00 45.29 C ATOM 1158 OD1 ASP A 184 25.386 42.391 6.406 1.00 46.13 O ATOM 1159 OD2 ASP A 184 25.565 40.940 8.062 1.00 45.51 O ATOM 1160 N GLU A 185 22.648 40.005 6.275 1.00 43.21 N ATOM 1161 CA GLU A 185 22.186 38.632 6.001 1.00 45.58 C ATOM 1162 C GLU A 185 22.968 37.572 6.816 1.00 43.50 C ATOM 1163 O GLU A 185 22.662 36.380 6.743 1.00 42.14 O ATOM 1164 CB GLU A 185 22.317 38.359 4.486 1.00 49.16 C ATOM 1165 CG GLU A 185 21.162 37.659 3.747 1.00 52.76 C ATOM 1166 CD GLU A 185 20.438 36.553 4.511 1.00 56.45 C ATOM 1167 OE1 GLU A 185 19.461 36.863 5.230 1.00 58.47 O ATOM 1168 OE2 GLU A 185 20.798 35.364 4.346 1.00 57.99 O ATOM 1169 N ASP A 186 23.962 38.006 7.594 1.00 42.54 N ATOM 1170 CA ASP A 186 24.799 37.094 8.379 1.00 42.61 C ATOM 1171 C ASP A 186 23.967 36.392 9.463 1.00 41.39 C ATOM 1172 O ASP A 186 23.043 37.003 9.992 1.00 39.90 O ATOM 1173 CB ASP A 186 25.949 37.865 9.029 1.00 43.97 C ATOM 1174 CG ASP A 186 26.963 36.954 9.681 1.00 46.94 C ATOM 1175 OD1 ASP A 186 27.845 36.412 8.968 1.00 47.97 O ATOM 1176 OD2 ASP A 186 26.868 36.765 10.913 1.00 48.56 O ATOM 1177 N PRO A 187 24.276 35.110 9.780 1.00 41.90 N ATOM 1178 CA PRO A 187 23.566 34.398 10.860 1.00 42.25 C ATOM 1179 C PRO A 187 23.545 35.109 12.213 1.00 42.42 C ATOM 1180 O PRO A 187 22.514 35.099 12.886 1.00 43.12 O ATOM 1181 CB PRO A 187 24.341 33.085 10.979 1.00 42.48 C ATOM 1182 CG PRO A 187 24.865 32.844 9.615 1.00 42.13 C ATOM 1183 CD PRO A 187 25.143 34.190 9.014 1.00 41.58 C ATOM 1184 N GLN A 188 24.672 35.703 12.600 1.00 43.22 N ATOM 1185 CA GLN A 188 24.745 36.548 13.799 1.00 44.53 C ATOM 1186 C GLN A 188 23.684 37.636 13.737 1.00 41.15 C ATOM 1187 O GLN A 188 22.911 37.808 14.680 1.00 40.88 O ATOM 1188 CB GLN A 188 26.130 37.208 13.924 1.00 47.52 C ATOM 1189 CG GLN A 188 26.349 38.021 15.199 1.00 50.91 C ATOM 1190 CD GLN A 188 27.340 39.158 15.008 1.00 54.55 C ATOM 1191 OE1 GLN A 188 28.558 38.950 15.016 1.00 59.03 O ATOM 1192 NE2 GLN A 188 26.823 40.371 14.840 1.00 55.25 N ATOM 1193 N ALA A 189 23.670 38.366 12.623 1.00 38.70 N ATOM 1194 CA ALA A 189 22.722 39.455 12.405 1.00 36.65 C ATOM 1195 C ALA A 189 21.284 38.951 12.435 1.00 35.86 C ATOM 1196 O ALA A 189 20.430 39.554 13.083 1.00 33.80 O ATOM 1197 CB ALA A 189 23.006 40.162 11.086 1.00 35.74 C ATOM 1198 N LEU A 190 21.031 37.842 11.743 1.00 35.95 N ATOM 1199 CA LEU A 190 19.687 37.266 11.662 1.00 36.79 C ATOM 1200 C LEU A 190 19.178 36.802 13.027 1.00 37.19 C ATOM 1201 O LEU A 190 17.999 36.982 13.335 1.00 36.40 O ATOM 1202 CB LEU A 190 19.641 36.109 10.651 1.00 36.94 C ATOM 1203 CG LEU A 190 19.874 36.462 9.174 1.00 37.28 C ATOM 1204 CD1 LEU A 190 19.968 35.187 8.345 1.00 37.29 C ATOM 1205 CD2 LEU A 190 18.798 37.396 8.632 1.00 37.18 C ATOM 1206 N LYS A 191 20.069 36.226 13.833 1.00 37.74 N ATOM 1207 CA LYS A 191 19.749 35.815 15.206 1.00 39.23 C ATOM 1208 C LYS A 191 19.372 37.014 16.083 1.00 38.38 C ATOM 1209 O LYS A 191 18.450 36.930 16.898 1.00 38.00 O ATOM 1210 CB LYS A 191 20.929 35.063 15.836 1.00 41.93 C ATOM 1211 CG LYS A 191 20.572 34.287 17.095 1.00 45.75 C ATOM 1212 CD LYS A 191 21.819 33.860 17.858 1.00 49.59 C ATOM 1213 CE LYS A 191 21.473 32.994 19.063 1.00 52.20 C ATOM 1214 NZ LYS A 191 20.598 33.704 20.042 1.00 54.17 N ATOM 1215 N CYS A 192 20.095 38.120 15.918 1.00 36.66 N ATOM 1216 CA CYS A 192 19.772 39.365 16.611 1.00 34.83 C ATOM 1217 C CYS A 192 18.400 39.902 16.200 1.00 34.87 C ATOM 1218 O CYS A 192 17.677 40.442 17.040 1.00 34.56 O ATOM 1219 CB CYS A 192 20.855 40.414 16.353 1.00 34.29 C ATOM 1220 SG CYS A 192 20.618 41.975 17.228 1.00 35.31 S ATOM 1221 N TYR A 193 18.042 39.746 14.922 1.00 34.83 N ATOM 1222 CA TYR A 193 16.741 40.195 14.402 1.00 35.04 C ATOM 1223 C TYR A 193 15.590 39.306 14.867 1.00 36.43 C ATOM 1224 O TYR A 193 14.491 39.800 15.088 1.00 36.66 O ATOM 1225 CB TYR A 193 16.732 40.300 12.864 1.00 34.23 C ATOM 1226 CG TYR A 193 17.884 41.084 12.262 1.00 34.24 C ATOM 1227 CD1 TYR A 193 18.497 42.154 12.955 1.00 35.10 C ATOM 1228 CD2 TYR A 193 18.369 40.767 10.991 1.00 34.23 C ATOM 1229 CE1 TYR A 193 19.562 42.860 12.402 1.00 34.36 C ATOM 1230 CE2 TYR A 193 19.429 41.471 10.430 1.00 34.08 C ATOM 1231 CZ TYR A 193 20.026 42.514 11.133 1.00 34.08 C ATOM 1232 OH TYR A 193 21.075 43.207 10.572 1.00 31.18 O ATOM 1233 N GLN A 194 15.841 38.005 15.002 1.00 39.18 N ATOM 1234 CA GLN A 194 14.860 37.070 15.574 1.00 41.72 C ATOM 1235 C GLN A 194 14.653 37.257 17.082 1.00 40.43 C ATOM 1236 O GLN A 194 13.605 36.894 17.613 1.00 40.53 O ATOM 1237 CB GLN A 194 15.287 35.622 15.321 1.00 45.13 C ATOM 1238 CG GLN A 194 15.206 35.192 13.863 1.00 48.57 C ATOM 1239 CD GLN A 194 16.036 33.949 13.579 1.00 52.57 C ATOM 1240 OE1 GLN A 194 16.289 33.135 14.476 1.00 54.73 O ATOM 1241 NE2 GLN A 194 16.471 33.799 12.329 1.00 54.02 N ATOM 1242 N ASP A 195 15.665 37.787 17.759 1.00 38.30 N ATOM 1243 CA ASP A 195 15.645 37.971 19.199 1.00 38.15 C ATOM 1244 C ASP A 195 15.144 39.385 19.556 1.00 38.70 C ATOM 1245 O ASP A 195 15.838 40.381 19.284 1.00 37.72 O ATOM 1246 CB ASP A 195 17.061 37.745 19.744 1.00 37.69 C ATOM 1247 CG ASP A 195 17.110 37.614 21.245 1.00 38.28 C ATOM 1248 OD1 ASP A 195 16.059 37.674 21.930 1.00 38.86 O ATOM 1249 OD2 ASP A 195 18.234 37.446 21.751 1.00 40.87 O ATOM 1250 N PRO A 196 13.939 39.493 20.158 1.00 39.07 N ATOM 1251 CA PRO A 196 13.551 40.803 20.727 1.00 37.98 C ATOM 1252 C PRO A 196 14.494 41.336 21.828 1.00 35.61 C ATOM 1253 O PRO A 196 14.486 42.536 22.100 1.00 34.60 O ATOM 1254 CB PRO A 196 12.136 40.556 21.282 1.00 39.03 C ATOM 1255 CG PRO A 196 11.888 39.084 21.167 1.00 39.77 C ATOM 1256 CD PRO A 196 12.796 38.564 20.103 1.00 39.21 C ATOM 1257 N GLY A 197 15.285 40.452 22.442 1.00 33.08 N ATOM 1258 CA GLY A 197 16.302 40.835 23.417 1.00 32.53 C ATOM 1259 C GLY A 197 17.593 41.428 22.883 1.00 32.51 C ATOM 1260 O GLY A 197 18.389 41.942 23.663 1.00 32.44 O ATOM 1261 N CYS A 198 17.814 41.347 21.571 1.00 33.03 N ATOM 1262 CA CYS A 198 18.980 41.949 20.928 1.00 32.81 C ATOM 1263 C CYS A 198 18.581 43.220 20.185 1.00 31.30 C ATOM 1264 O CYS A 198 17.739 43.162 19.288 1.00 30.54 O ATOM 1265 CB CYS A 198 19.607 40.962 19.945 1.00 33.10 C ATOM 1266 SG CYS A 198 21.128 41.573 19.180 1.00 35.18 S ATOM 1267 N CYS A 199 19.181 44.352 20.555 1.00 30.58 N ATOM 1268 CA CYS A 199 19.003 45.617 19.833 1.00 30.85 C ATOM 1269 C CYS A 199 20.359 46.214 19.423 1.00 32.31 C ATOM 1270 O CYS A 199 20.614 47.403 19.605 1.00 33.49 O ATOM 1271 CB CYS A 199 18.187 46.607 20.682 1.00 29.54 C ATOM 1272 SG CYS A 199 17.531 48.031 19.778 1.00 27.72 S ATOM 1273 N ASP A 200 21.231 45.371 18.875 1.00 34.34 N ATOM 1274 CA ASP A 200 22.464 45.836 18.224 1.00 34.98 C ATOM 1275 C ASP A 200 22.108 46.266 16.816 1.00 32.20 C ATOM 1276 O ASP A 200 21.498 45.505 16.062 1.00 31.55 O ATOM 1277 CB ASP A 200 23.527 44.730 18.152 1.00 37.13 C ATOM 1278 CG ASP A 200 24.054 44.326 19.516 1.00 39.95 C ATOM 1279 OD1 ASP A 200 23.609 44.883 20.545 1.00 42.59 O ATOM 1280 OD2 ASP A 200 24.928 43.439 19.561 1.00 43.45 O ATOM 1281 N PHE A 201 22.503 47.482 16.459 1.00 30.88 N ATOM 1282 CA PHE A 201 22.246 48.030 15.134 1.00 29.57 C ATOM 1283 C PHE A 201 23.281 47.448 14.162 1.00 29.15 C ATOM 1284 O PHE A 201 24.192 48.147 13.714 1.00 29.06 O ATOM 1285 CB PHE A 201 22.274 49.574 15.202 1.00 28.66 C ATOM 1286 CG PHE A 201 21.643 50.276 14.019 1.00 28.86 C ATOM 1287 CD1 PHE A 201 20.482 49.793 13.402 1.00 28.74 C ATOM 1288 CD2 PHE A 201 22.188 51.471 13.551 1.00 29.02 C ATOM 1289 CE1 PHE A 201 19.910 50.469 12.332 1.00 28.91 C ATOM 1290 CE2 PHE A 201 21.616 52.148 12.482 1.00 29.02 C ATOM 1291 CZ PHE A 201 20.474 51.649 11.875 1.00 28.77 C ATOM 1292 N VAL A 202 23.119 46.153 13.867 1.00 28.01 N ATOM 1293 CA VAL A 202 23.971 45.419 12.937 1.00 28.04 C ATOM 1294 C VAL A 202 23.438 45.722 11.540 1.00 27.43 C ATOM 1295 O VAL A 202 22.270 45.456 11.235 1.00 27.24 O ATOM 1296 CB VAL A 202 23.924 43.886 13.169 1.00 29.06 C ATOM 1297 CG1 VAL A 202 24.876 43.168 12.217 1.00 29.54 C ATOM 1298 CG2 VAL A 202 24.270 43.537 14.606 1.00 29.34 C ATOM 1299 N THR A 203 24.284 46.299 10.699 1.00 26.49 N ATOM 1300 CA THR A 203 23.840 46.806 9.411 1.00 26.76 C ATOM 1301 C THR A 203 24.692 46.242 8.295 1.00 25.79 C ATOM 1302 O THR A 203 25.843 45.872 8.513 1.00 25.62 O ATOM 1303 CB THR A 203 23.886 48.351 9.358 1.00 26.68 C ATOM 1304 OG1 THR A 203 25.242 48.808 9.454 1.00 27.21 O ATOM 1305 CG2 THR A 203 23.083 48.953 10.499 1.00 26.70 C ATOM 1306 N ASN A 204 24.106 46.167 7.106 1.00 25.40 N ATOM 1307 CA ASN A 204 24.867 45.915 5.887 1.00 24.61 C ATOM 1308 C ASN A 204 25.698 47.156 5.521 1.00 25.19 C ATOM 1309 O ASN A 204 25.349 48.283 5.872 1.00 24.30 O ATOM 1310 CB ASN A 204 23.936 45.477 4.741 1.00 24.55 C ATOM 1311 CG ASN A 204 22.980 46.571 4.296 1.00 24.81 C ATOM 1312 OD1 ASN A 204 23.407 47.592 3.764 1.00 26.28 O ATOM 1313 ND2 ASN A 204 21.681 46.354 4.481 1.00 24.87 N ATOM 1314 N ARG A 205 26.825 46.916 4.864 1.00 26.56 N ATOM 1315 CA ARG A 205 27.753 47.945 4.387 1.00 27.28 C ATOM 1316 C ARG A 205 27.142 49.020 3.487 1.00 25.39 C ATOM 1317 O ARG A 205 27.525 50.186 3.582 1.00 24.84 O ATOM 1318 CB ARG A 205 28.925 47.294 3.644 1.00 30.29 C ATOM 1319 CG ARG A 205 29.813 46.392 4.488 1.00 34.05 C ATOM 1320 CD ARG A 205 30.775 45.610 3.606 1.00 38.75 C ATOM 1321 NE ARG A 205 31.481 44.544 4.325 1.00 42.95 N ATOM 1322 CZ ARG A 205 32.555 43.888 3.868 1.00 46.92 C ATOM 1323 NH1 ARG A 205 33.087 44.169 2.671 1.00 48.37 N ATOM 1324 NH2 ARG A 205 33.115 42.941 4.621 1.00 48.38 N ATOM 1325 N ALA A 206 26.220 48.634 2.608 1.00 24.86 N ATOM 1326 CA ALA A 206 25.564 49.598 1.710 1.00 24.73 C ATOM 1327 C ALA A 206 24.820 50.677 2.490 1.00 23.94 C ATOM 1328 O ALA A 206 25.001 51.872 2.240 1.00 22.53 O ATOM 1329 CB ALA A 206 24.610 48.896 0.753 1.00 24.89 C ATOM 1330 N TYR A 207 23.994 50.240 3.440 1.00 23.77 N ATOM 1331 CA TYR A 207 23.265 51.161 4.311 1.00 23.89 C ATOM 1332 C TYR A 207 24.206 52.004 5.182 1.00 23.13 C ATOM 1333 O TYR A 207 24.026 53.222 5.294 1.00 23.40 O ATOM 1334 CB TYR A 207 22.265 50.424 5.207 1.00 24.35 C ATOM 1335 CG TYR A 207 21.715 51.324 6.282 1.00 25.02 C ATOM 1336 CD1 TYR A 207 20.682 52.212 6.011 1.00 25.83 C ATOM 1337 CD2 TYR A 207 22.267 51.330 7.561 1.00 25.50 C ATOM 1338 CE1 TYR A 207 20.193 53.065 6.991 1.00 26.22 C ATOM 1339 CE2 TYR A 207 21.788 52.176 8.547 1.00 25.63 C ATOM 1340 CZ TYR A 207 20.754 53.045 8.261 1.00 25.97 C ATOM 1341 OH TYR A 207 20.281 53.887 9.245 1.00 26.56 O ATOM 1342 N ALA A 208 25.190 51.355 5.796 1.00 21.60 N ATOM 1343 CA ALA A 208 26.129 52.037 6.686 1.00 21.18 C ATOM 1344 C ALA A 208 26.890 53.166 6.011 1.00 20.77 C ATOM 1345 O ALA A 208 26.981 54.259 6.559 1.00 20.11 O ATOM 1346 CB ALA A 208 27.117 51.042 7.275 1.00 21.30 C ATOM 1347 N ILE A 209 27.441 52.891 4.829 1.00 20.57 N ATOM 1348 CA ILE A 209 28.210 53.885 4.086 1.00 20.62 C ATOM 1349 C ILE A 209 27.285 54.994 3.597 1.00 20.06 C ATOM 1350 O ILE A 209 27.566 56.173 3.809 1.00 20.26 O ATOM 1351 CB ILE A 209 28.999 53.245 2.907 1.00 21.45 C ATOM 1352 CG1 ILE A 209 30.104 52.331 3.444 1.00 21.98 C ATOM 1353 CG2 ILE A 209 29.633 54.312 2.018 1.00 21.24 C ATOM 1354 CD1 ILE A 209 30.538 51.262 2.468 1.00 22.70 C ATOM 1355 N ALA A 210 26.178 54.613 2.966 1.00 19.70 N ATOM 1356 CA ALA A 210 25.244 55.583 2.390 1.00 19.59 C ATOM 1357 C ALA A 210 24.572 56.468 3.434 1.00 19.55 C ATOM 1358 O ALA A 210 24.510 57.679 3.259 1.00 19.55 O ATOM 1359 CB ALA A 210 24.195 54.877 1.548 1.00 19.77 C ATOM 1360 N SER A 211 24.081 55.877 4.520 1.00 19.78 N ATOM 1361 CA SER A 211 23.435 56.662 5.586 1.00 20.09 C ATOM 1362 C SER A 211 24.418 57.626 6.259 1.00 20.17 C ATOM 1363 O SER A 211 24.091 58.790 6.482 1.00 20.03 O ATOM 1364 CB SER A 211 22.815 55.747 6.636 1.00 20.17 C ATOM 1365 OG SER A 211 23.815 55.027 7.328 1.00 20.37 O ATOM 1366 N SER A 212 25.619 57.130 6.565 1.00 20.21 N ATOM 1367 CA SER A 212 26.698 57.953 7.136 1.00 20.27 C ATOM 1368 C SER A 212 27.123 59.128 6.269 1.00 20.61 C ATOM 1369 O SER A 212 27.473 60.179 6.798 1.00 20.63 O ATOM 1370 CB SER A 212 27.927 57.098 7.416 1.00 20.10 C ATOM 1371 OG SER A 212 27.628 56.155 8.415 1.00 21.11 O ATOM 1372 N ILE A 213 27.121 58.938 4.950 1.00 21.44 N ATOM 1373 CA ILE A 213 27.448 60.006 4.010 1.00 22.13 C ATOM 1374 C ILE A 213 26.377 61.104 4.024 1.00 22.40 C ATOM 1375 O ILE A 213 26.681 62.277 4.207 1.00 21.79 O ATOM 1376 CB ILE A 213 27.649 59.451 2.576 1.00 22.70 C ATOM 1377 CG1 ILE A 213 28.994 58.723 2.474 1.00 23.05 C ATOM 1378 CG2 ILE A 213 27.622 60.571 1.536 1.00 23.14 C ATOM 1379 CD1 ILE A 213 29.060 57.714 1.342 1.00 23.42 C ATOM 1380 N ILE A 214 25.131 60.700 3.811 1.00 23.92 N ATOM 1381 CA ILE A 214 23.993 61.620 3.731 1.00 25.17 C ATOM 1382 C ILE A 214 23.716 62.322 5.060 1.00 25.00 C ATOM 1383 O ILE A 214 23.394 63.508 5.075 1.00 24.93 O ATOM 1384 CB ILE A 214 22.712 60.875 3.249 1.00 26.74 C ATOM 1385 CG1 ILE A 214 22.832 60.555 1.759 1.00 27.60 C ATOM 1386 CG2 ILE A 214 21.437 61.687 3.508 1.00 27.45 C ATOM 1387 CD1 ILE A 214 21.694 59.710 1.213 1.00 28.75 C ATOM 1388 N SER A 215 23.818 61.587 6.164 1.00 24.97 N ATOM 1389 CA SER A 215 23.424 62.115 7.472 1.00 25.11 C ATOM 1390 C SER A 215 24.546 62.718 8.295 1.00 24.43 C ATOM 1391 O SER A 215 24.247 63.365 9.285 1.00 24.70 O ATOM 1392 CB SER A 215 22.743 61.031 8.305 1.00 25.55 C ATOM 1393 OG SER A 215 21.472 60.692 7.776 1.00 26.55 O ATOM 1394 N PHE A 216 25.812 62.514 7.915 1.00 23.90 N ATOM 1395 CA PHE A 216 26.942 62.991 8.723 1.00 23.49 C ATOM 1396 C PHE A 216 28.103 63.574 7.905 1.00 23.61 C ATOM 1397 O PHE A 216 28.392 64.767 8.019 1.00 22.94 O ATOM 1398 CB PHE A 216 27.443 61.877 9.660 1.00 23.25 C ATOM 1399 CG PHE A 216 28.590 62.297 10.538 1.00 22.49 C ATOM 1400 CD1 PHE A 216 28.369 63.117 11.647 1.00 22.35 C ATOM 1401 CD2 PHE A 216 29.891 61.900 10.247 1.00 21.80 C ATOM 1402 CE1 PHE A 216 29.426 63.521 12.449 1.00 21.92 C ATOM 1403 CE2 PHE A 216 30.950 62.301 11.047 1.00 21.75 C ATOM 1404 CZ PHE A 216 30.717 63.111 12.151 1.00 21.69 C ATOM 1405 N TYR A 217 28.764 62.755 7.091 1.00 24.27 N ATOM 1406 CA TYR A 217 30.003 63.197 6.412 1.00 25.26 C ATOM 1407 C TYR A 217 29.818 64.412 5.502 1.00 26.33 C ATOM 1408 O TYR A 217 30.636 65.328 5.537 1.00 26.56 O ATOM 1409 CB TYR A 217 30.673 62.063 5.627 1.00 24.85 C ATOM 1410 CG TYR A 217 31.314 61.016 6.506 1.00 25.30 C ATOM 1411 CD1 TYR A 217 32.439 61.324 7.282 1.00 25.79 C ATOM 1412 CD2 TYR A 217 30.813 59.713 6.561 1.00 25.24 C ATOM 1413 CE1 TYR A 217 33.037 60.371 8.098 1.00 25.94 C ATOM 1414 CE2 TYR A 217 31.409 58.751 7.366 1.00 26.23 C ATOM 1415 CZ TYR A 217 32.519 59.085 8.135 1.00 26.55 C ATOM 1416 OH TYR A 217 33.108 58.136 8.939 1.00 27.85 O ATOM 1417 N ILE A 218 28.760 64.419 4.693 1.00 27.08 N ATOM 1418 CA ILE A 218 28.485 65.565 3.816 1.00 27.77 C ATOM 1419 C ILE A 218 28.161 66.836 4.604 1.00 26.32 C ATOM 1420 O ILE A 218 28.801 67.867 4.379 1.00 26.35 O ATOM 1421 CB ILE A 218 27.382 65.257 2.762 1.00 29.05 C ATOM 1422 CG1 ILE A 218 27.901 64.223 1.752 1.00 30.19 C ATOM 1423 CG2 ILE A 218 26.913 66.522 2.037 1.00 29.00 C ATOM 1424 CD1 ILE A 218 29.231 64.557 1.104 1.00 30.57 C ATOM 1425 N PRO A 219 27.177 66.777 5.517 1.00 24.94 N ATOM 1426 CA PRO A 219 26.948 68.003 6.281 1.00 24.43 C ATOM 1427 C PRO A 219 28.153 68.427 7.155 1.00 24.33 C ATOM 1428 O PRO A 219 28.417 69.630 7.267 1.00 23.83 O ATOM 1429 CB PRO A 219 25.691 67.688 7.105 1.00 24.37 C ATOM 1430 CG PRO A 219 25.553 66.206 7.082 1.00 24.50 C ATOM 1431 CD PRO A 219 26.157 65.748 5.795 1.00 24.43 C ATOM 1432 N LEU A 220 28.890 67.467 7.722 1.00 23.98 N ATOM 1433 CA LEU A 220 30.103 67.793 8.498 1.00 24.73 C ATOM 1434 C LEU A 220 31.165 68.524 7.670 1.00 25.33 C ATOM 1435 O LEU A 220 31.737 69.510 8.145 1.00 24.69 O ATOM 1436 CB LEU A 220 30.741 66.545 9.121 1.00 24.89 C ATOM 1437 CG LEU A 220 31.837 66.845 10.155 1.00 25.00 C ATOM 1438 CD1 LEU A 220 31.206 67.227 11.484 1.00 25.45 C ATOM 1439 CD2 LEU A 220 32.777 65.664 10.330 1.00 25.19 C ATOM 1440 N LEU A 221 31.417 68.043 6.447 1.00 25.52 N ATOM 1441 CA LEU A 221 32.413 68.656 5.557 1.00 25.58 C ATOM 1442 C LEU A 221 31.990 70.038 5.067 1.00 25.04 C ATOM 1443 O LEU A 221 32.812 70.950 4.999 1.00 24.24 O ATOM 1444 CB LEU A 221 32.732 67.743 4.373 1.00 26.48 C ATOM 1445 CG LEU A 221 33.417 66.420 4.744 1.00 28.15 C ATOM 1446 CD1 LEU A 221 33.321 65.430 3.587 1.00 28.88 C ATOM 1447 CD2 LEU A 221 34.868 66.619 5.179 1.00 28.52 C ATOM 1448 N ILE A 222 30.712 70.197 4.742 1.00 25.57 N ATOM 1449 CA ILE A 222 30.174 71.511 4.372 1.00 25.71 C ATOM 1450 C ILE A 222 30.284 72.479 5.556 1.00 25.56 C ATOM 1451 O ILE A 222 30.713 73.615 5.378 1.00 26.13 O ATOM 1452 CB ILE A 222 28.712 71.421 3.870 1.00 26.54 C ATOM 1453 CG1 ILE A 222 28.663 70.669 2.530 1.00 26.76 C ATOM 1454 CG2 ILE A 222 28.112 72.815 3.686 1.00 26.72 C ATOM 1455 CD1 ILE A 222 27.270 70.310 2.057 1.00 26.83 C ATOM 1456 N MET A 223 29.904 72.022 6.751 1.00 24.98 N ATOM 1457 CA MET A 223 29.988 72.836 7.978 1.00 24.61 C ATOM 1458 C MET A 223 31.408 73.336 8.236 1.00 23.70 C ATOM 1459 O MET A 223 31.613 74.514 8.496 1.00 22.13 O ATOM 1460 CB MET A 223 29.495 72.021 9.182 1.00 24.83 C ATOM 1461 CG MET A 223 29.474 72.751 10.518 1.00 25.18 C ATOM 1462 SD MET A 223 29.496 71.615 11.921 1.00 26.25 S ATOM 1463 CE MET A 223 31.174 70.987 11.818 1.00 26.27 C ATOM 1464 N ILE A 224 32.376 72.427 8.165 1.00 24.76 N ATOM 1465 CA ILE A 224 33.798 72.767 8.380 1.00 25.29 C ATOM 1466 C ILE A 224 34.311 73.759 7.328 1.00 26.50 C ATOM 1467 O ILE A 224 34.884 74.796 7.671 1.00 27.00 O ATOM 1468 CB ILE A 224 34.682 71.496 8.404 1.00 24.43 C ATOM 1469 CG1 ILE A 224 34.403 70.697 9.687 1.00 24.38 C ATOM 1470 CG2 ILE A 224 36.167 71.843 8.323 1.00 24.28 C ATOM 1471 CD1 ILE A 224 34.851 69.251 9.627 1.00 24.22 C ATOM 1472 N PHE A 225 34.104 73.424 6.059 1.00 27.06 N ATOM 1473 CA PHE A 225 34.535 74.266 4.945 1.00 28.78 C ATOM 1474 C PHE A 225 34.003 75.700 5.083 1.00 28.49 C ATOM 1475 O PHE A 225 34.776 76.657 5.077 1.00 27.85 O ATOM 1476 CB PHE A 225 34.076 73.629 3.627 1.00 30.73 C ATOM 1477 CG PHE A 225 34.353 74.461 2.408 1.00 32.39 C ATOM 1478 CD1 PHE A 225 35.653 74.641 1.955 1.00 34.26 C ATOM 1479 CD2 PHE A 225 33.307 75.043 1.691 1.00 34.00 C ATOM 1480 CE1 PHE A 225 35.912 75.404 0.818 1.00 35.10 C ATOM 1481 CE2 PHE A 225 33.556 75.805 0.556 1.00 34.44 C ATOM 1482 CZ PHE A 225 34.861 75.988 0.119 1.00 34.93 C ATOM 1483 N VAL A 226 32.688 75.818 5.258 1.00 28.00 N ATOM 1484 CA VAL A 226 32.007 77.104 5.359 1.00 27.55 C ATOM 1485 C VAL A 226 32.400 77.853 6.633 1.00 28.22 C ATOM 1486 O VAL A 226 32.652 79.060 6.578 1.00 28.89 O ATOM 1487 CB VAL A 226 30.467 76.935 5.276 1.00 28.01 C ATOM 1488 CG1 VAL A 226 29.741 78.254 5.550 1.00 27.75 C ATOM 1489 CG2 VAL A 226 30.072 76.394 3.902 1.00 28.21 C ATOM 1490 N ALA A 227 32.455 77.152 7.768 1.00 28.22 N ATOM 1491 CA ALA A 227 32.879 77.772 9.040 1.00 28.65 C ATOM 1492 C ALA A 227 34.288 78.387 8.966 1.00 28.89 C ATOM 1493 O ALA A 227 34.522 79.467 9.506 1.00 28.06 O ATOM 1494 CB ALA A 227 32.794 76.776 10.190 1.00 27.71 C ATOM 1495 N LEU A 228 35.211 77.707 8.287 1.00 30.28 N ATOM 1496 CA LEU A 228 36.576 78.221 8.113 1.00 31.42 C ATOM 1497 C LEU A 228 36.593 79.503 7.299 1.00 32.85 C ATOM 1498 O LEU A 228 37.377 80.407 7.588 1.00 32.85 O ATOM 1499 CB LEU A 228 37.478 77.184 7.444 1.00 31.70 C ATOM 1500 CG LEU A 228 37.764 75.931 8.275 1.00 32.21 C ATOM 1501 CD1 LEU A 228 38.254 74.797 7.377 1.00 32.63 C ATOM 1502 CD2 LEU A 228 38.752 76.229 9.394 1.00 31.78 C ATOM 1503 N ARG A 229 35.740 79.576 6.278 1.00 35.03 N ATOM 1504 CA ARG A 229 35.604 80.797 5.491 1.00 37.22 C ATOM 1505 C ARG A 229 34.989 81.937 6.315 1.00 35.38 C ATOM 1506 O ARG A 229 35.428 83.076 6.186 1.00 35.13 O ATOM 1507 CB ARG A 229 34.793 80.558 4.208 1.00 40.45 C ATOM 1508 CG ARG A 229 35.325 79.503 3.234 1.00 44.76 C ATOM 1509 CD ARG A 229 36.823 79.557 2.927 1.00 50.19 C ATOM 1510 NE ARG A 229 37.547 78.322 3.299 1.00 57.13 N ATOM 1511 CZ ARG A 229 38.500 78.197 4.240 1.00 61.81 C ATOM 1512 NH1 ARG A 229 38.908 79.225 4.994 1.00 63.26 N ATOM 1513 NH2 ARG A 229 39.063 77.002 4.439 1.00 63.24 N ATOM 1514 N VAL A 230 33.993 81.628 7.154 1.00 34.65 N ATOM 1515 CA VAL A 230 33.410 82.603 8.111 1.00 34.79 C ATOM 1516 C VAL A 230 34.481 83.134 9.064 1.00 34.28 C ATOM 1517 O VAL A 230 34.569 84.342 9.299 1.00 31.58 O ATOM 1518 CB VAL A 230 32.238 81.997 8.944 1.00 33.89 C ATOM 1519 CG1 VAL A 230 31.875 82.871 10.144 1.00 33.77 C ATOM 1520 CG2 VAL A 230 31.010 81.780 8.072 1.00 33.14 C ATOM 1521 N TYR A 231 35.274 82.216 9.607 1.00 36.05 N ATOM 1522 CA TYR A 231 36.408 82.559 10.467 1.00 39.68 C ATOM 1523 C TYR A 231 37.345 83.514 9.742 1.00 41.25 C ATOM 1524 O TYR A 231 37.691 84.569 10.277 1.00 40.08 O ATOM 1525 CB TYR A 231 37.141 81.282 10.904 1.00 41.39 C ATOM 1526 CG TYR A 231 38.331 81.433 11.840 1.00 45.17 C ATOM 1527 CD1 TYR A 231 38.560 82.598 12.588 1.00 47.12 C ATOM 1528 CD2 TYR A 231 39.218 80.375 12.010 1.00 48.68 C ATOM 1529 CE1 TYR A 231 39.649 82.704 13.439 1.00 48.12 C ATOM 1530 CE2 TYR A 231 40.306 80.478 12.865 1.00 50.08 C ATOM 1531 CZ TYR A 231 40.514 81.643 13.577 1.00 48.82 C ATOM 1532 OH TYR A 231 41.591 81.742 14.420 1.00 52.10 O ATOM 1533 N ARG A 232 37.710 83.150 8.515 1.00 44.05 N ATOM 1534 CA ARG A 232 38.580 83.969 7.670 1.00 46.99 C ATOM 1535 C ARG A 232 38.004 85.369 7.420 1.00 45.70 C ATOM 1536 O ARG A 232 38.725 86.358 7.528 1.00 44.99 O ATOM 1537 CB ARG A 232 38.826 83.261 6.329 1.00 51.12 C ATOM 1538 CG ARG A 232 39.938 83.864 5.475 1.00 55.15 C ATOM 1539 CD ARG A 232 39.885 83.340 4.045 1.00 58.25 C ATOM 1540 NE ARG A 232 40.482 82.006 3.895 1.00 61.07 N ATOM 1541 CZ ARG A 232 40.188 81.124 2.931 1.00 64.62 C ATOM 1542 NH1 ARG A 232 39.258 81.376 2.003 1.00 64.96 N ATOM 1543 NH2 ARG A 232 40.818 79.949 2.907 1.00 65.58 N ATOM 1544 N GLU A 233 36.713 85.437 7.095 1.00 44.22 N ATOM 1545 CA GLU A 233 36.041 86.703 6.756 1.00 43.62 C ATOM 1546 C GLU A 233 35.817 87.594 7.982 1.00 42.99 C ATOM 1547 O GLU A 233 35.962 88.813 7.889 1.00 42.10 O ATOM 1548 CB GLU A 233 34.710 86.417 6.046 1.00 45.13 C ATOM 1549 CG GLU A 233 33.820 87.623 5.752 1.00 46.97 C ATOM 1550 CD GLU A 233 34.422 88.604 4.759 1.00 49.38 C ATOM 1551 OE1 GLU A 233 34.960 88.156 3.720 1.00 51.03 O ATOM 1552 OE2 GLU A 233 34.326 89.828 5.003 1.00 49.24 O ATOM 1553 N ALA A 234 35.437 86.995 9.110 1.00 41.83 N ATOM 1554 CA ALA A 234 35.356 87.723 10.379 1.00 43.04 C ATOM 1555 C ALA A 234 36.724 88.324 10.705 1.00 45.51 C ATOM 1556 O ALA A 234 36.849 89.533 10.928 1.00 43.00 O ATOM 1557 CB ALA A 234 34.900 86.804 11.505 1.00 42.17 C ATOM 1558 N LYS A 235 37.742 87.467 10.681 1.00 47.33 N ATOM 1559 CA LYS A 235 39.131 87.866 10.920 1.00 51.13 C ATOM 1560 C LYS A 235 39.574 89.042 10.043 1.00 52.58 C ATOM 1561 O LYS A 235 40.326 89.884 10.508 1.00 53.00 O ATOM 1562 CB LYS A 235 40.067 86.673 10.705 1.00 54.42 C ATOM 1563 CG LYS A 235 41.480 86.828 11.243 1.00 58.44 C ATOM 1564 CD LYS A 235 42.326 85.628 10.819 1.00 62.77 C ATOM 1565 CE LYS A 235 43.476 85.344 11.773 1.00 65.79 C ATOM 1566 NZ LYS A 235 44.054 83.992 11.527 1.00 67.83 N ATOM 1567 N GLU A 236 39.115 89.100 8.790 1.00 53.78 N ATOM 1568 CA GLU A 236 39.428 90.236 7.901 1.00 53.74 C ATOM 1569 C GLU A 236 38.648 91.523 8.199 1.00 54.01 C ATOM 1570 O GLU A 236 39.187 92.619 8.021 1.00 52.75 O ATOM 1571 CB GLU A 236 39.247 89.852 6.426 1.00 54.27 C ATOM 1572 CG GLU A 236 40.294 88.884 5.890 1.00 55.94 C ATOM 1573 CD GLU A 236 41.724 89.314 6.184 1.00 57.64 C ATOM 1574 OE1 GLU A 236 42.036 90.517 6.043 1.00 59.81 O ATOM 1575 OE2 GLU A 236 42.541 88.448 6.565 1.00 59.19 O ATOM 1576 N GLN A 237 37.397 91.394 8.644 1.00 54.50 N ATOM 1577 CA GLN A 237 36.556 92.559 8.952 1.00 54.60 C ATOM 1578 C GLN A 237 37.030 93.390 10.159 1.00 56.25 C ATOM 1579 O GLN A 237 36.903 94.620 10.146 1.00 57.11 O ATOM 1580 CB GLN A 237 35.088 92.147 9.121 1.00 54.06 C ATOM 1581 CG GLN A 237 34.394 91.869 7.795 1.00 54.24 C ATOM 1582 CD GLN A 237 32.905 91.590 7.924 1.00 54.64 C ATOM 1583 OE1 GLN A 237 32.308 91.749 8.991 1.00 54.41 O ATOM 1584 NE2 GLN A 237 32.296 91.170 6.823 1.00 56.64 N ATOM 1585 N ILE A 238 37.550 92.731 11.194 1.00 57.23 N ATOM 1586 CA ILE A 238 38.211 93.452 12.306 1.00 61.07 C ATOM 1587 C ILE A 238 39.499 94.156 11.878 1.00 63.41 C ATOM 1588 O ILE A 238 39.791 95.237 12.386 1.00 65.44 O ATOM 1589 CB ILE A 238 38.555 92.577 13.544 1.00 60.52 C ATOM 1590 CG1 ILE A 238 39.124 91.216 13.132 1.00 61.98 C ATOM 1591 CG2 ILE A 238 37.353 92.454 14.468 1.00 60.42 C ATOM 1592 CD1 ILE A 238 40.024 90.590 14.163 1.00 62.90 C ATOM 1593 N ARG A 239 40.258 93.556 10.960 1.00 64.87 N ATOM 1594 CA ARG A 239 41.544 94.124 10.530 1.00 67.28 C ATOM 1595 C ARG A 239 41.337 95.390 9.697 1.00 66.50 C ATOM 1596 O ARG A 239 42.072 96.360 9.871 1.00 67.44 O ATOM 1597 CB ARG A 239 42.379 93.107 9.739 1.00 69.91 C ATOM 1598 CG ARG A 239 42.731 91.835 10.498 1.00 72.78 C ATOM 1599 CD ARG A 239 43.846 92.013 11.514 1.00 76.09 C ATOM 1600 NE ARG A 239 43.996 90.816 12.349 1.00 79.32 N ATOM 1601 CZ ARG A 239 44.578 89.674 11.972 1.00 82.87 C ATOM 1602 NH1 ARG A 239 45.098 89.527 10.750 1.00 85.02 N ATOM 1603 NH2 ARG A 239 44.647 88.657 12.830 1.00 85.42 N ATOM 1604 N LYS A 240 40.327 95.375 8.819 1.00 64.69 N ATOM 1605 CA LYS A 240 39.958 96.517 7.952 1.00 63.24 C ATOM 1606 C LYS A 240 41.153 97.195 7.278 1.00 60.41 C ATOM 1607 O LYS A 240 41.728 96.653 6.335 1.00 58.19 O ATOM 1608 CB LYS A 240 39.064 97.552 8.681 1.00 63.91 C ATOM 1609 CG LYS A 240 39.066 97.512 10.208 1.00 65.41 C ATOM 1610 CD LYS A 240 38.076 98.493 10.817 1.00 65.68 C ATOM 1611 CE LYS A 240 36.664 97.933 10.853 1.00 66.57 C ATOM 1612 NZ LYS A 240 35.665 98.988 11.177 1.00 66.81 N ATOM 1613 N ARG A 275 33.261 97.093 6.546 1.00 52.06 N ATOM 1614 CA ARG A 275 32.111 97.446 7.373 1.00 52.84 C ATOM 1615 C ARG A 275 32.245 98.872 7.911 1.00 53.63 C ATOM 1616 O ARG A 275 33.332 99.284 8.337 1.00 51.16 O ATOM 1617 CB ARG A 275 31.969 96.476 8.555 1.00 52.46 C ATOM 1618 CG ARG A 275 31.611 95.040 8.185 1.00 52.44 C ATOM 1619 CD ARG A 275 30.115 94.838 7.967 1.00 53.03 C ATOM 1620 NE ARG A 275 29.318 95.079 9.176 1.00 51.31 N ATOM 1621 CZ ARG A 275 29.061 94.194 10.146 1.00 48.69 C ATOM 1622 NH1 ARG A 275 29.528 92.944 10.112 1.00 47.58 N ATOM 1623 NH2 ARG A 275 28.318 94.578 11.180 1.00 47.94 N ATOM 1624 N LYS A 276 31.132 99.607 7.897 1.00 55.26 N ATOM 1625 CA LYS A 276 31.058 100.940 8.505 1.00 57.59 C ATOM 1626 C LYS A 276 31.077 100.814 10.033 1.00 56.72 C ATOM 1627 O LYS A 276 31.644 101.666 10.722 1.00 58.77 O ATOM 1628 CB LYS A 276 29.784 101.673 8.072 1.00 60.17 C ATOM 1629 CG LYS A 276 29.581 101.785 6.564 1.00 62.33 C ATOM 1630 CD LYS A 276 28.142 101.475 6.164 1.00 65.06 C ATOM 1631 CE LYS A 276 28.026 101.101 4.689 1.00 67.49 C ATOM 1632 NZ LYS A 276 26.615 101.104 4.198 1.00 68.16 N ATOM 1633 N THR A 277 30.442 99.750 10.536 1.00 54.19 N ATOM 1634 CA THR A 277 30.428 99.375 11.958 1.00 53.50 C ATOM 1635 C THR A 277 31.748 99.620 12.704 1.00 51.25 C ATOM 1636 O THR A 277 32.834 99.353 12.186 1.00 49.86 O ATOM 1637 CB THR A 277 30.088 97.869 12.118 1.00 54.75 C ATOM 1638 OG1 THR A 277 28.955 97.528 11.312 1.00 56.97 O ATOM 1639 CG2 THR A 277 29.786 97.510 13.562 1.00 54.18 C ATOM 1640 N SER A 278 31.628 100.124 13.927 1.00 50.54 N ATOM 1641 CA SER A 278 32.753 100.238 14.861 1.00 50.34 C ATOM 1642 C SER A 278 33.484 98.902 15.077 1.00 50.38 C ATOM 1643 O SER A 278 32.872 97.835 15.027 1.00 50.07 O ATOM 1644 CB SER A 278 32.240 100.750 16.211 1.00 50.78 C ATOM 1645 OG SER A 278 33.209 100.583 17.225 1.00 51.58 O ATOM 1646 N ARG A 279 34.784 98.977 15.349 1.00 49.11 N ATOM 1647 CA ARG A 279 35.602 97.786 15.592 1.00 49.03 C ATOM 1648 C ARG A 279 35.238 97.056 16.900 1.00 49.82 C ATOM 1649 O ARG A 279 35.399 95.834 16.979 1.00 49.43 O ATOM 1650 CB ARG A 279 37.083 98.164 15.575 1.00 50.66 C ATOM 1651 CG ARG A 279 38.059 97.000 15.577 1.00 52.10 C ATOM 1652 CD ARG A 279 39.482 97.504 15.388 1.00 53.80 C ATOM 1653 NE ARG A 279 40.456 96.693 16.129 1.00 57.43 N ATOM 1654 CZ ARG A 279 41.313 95.808 15.610 1.00 59.31 C ATOM 1655 NH1 ARG A 279 41.376 95.566 14.302 1.00 60.13 N ATOM 1656 NH2 ARG A 279 42.136 95.151 16.424 1.00 61.00 N ATOM 1657 N VAL A 280 34.743 97.788 17.907 1.00 49.90 N ATOM 1658 CA VAL A 280 34.277 97.165 19.164 1.00 50.20 C ATOM 1659 C VAL A 280 32.938 96.444 18.986 1.00 50.94 C ATOM 1660 O VAL A 280 32.705 95.413 19.620 1.00 50.95 O ATOM 1661 CB VAL A 280 34.196 98.153 20.371 1.00 51.37 C ATOM 1662 CG1 VAL A 280 35.539 98.834 20.604 1.00 51.35 C ATOM 1663 CG2 VAL A 280 33.072 99.184 20.224 1.00 51.12 C ATOM 1664 N MET A 281 32.059 96.998 18.147 1.00 52.31 N ATOM 1665 CA MET A 281 30.817 96.315 17.748 1.00 52.25 C ATOM 1666 C MET A 281 31.107 95.013 17.004 1.00 48.14 C ATOM 1667 O MET A 281 30.420 94.015 17.219 1.00 46.15 O ATOM 1668 CB MET A 281 29.952 97.210 16.852 1.00 56.64 C ATOM 1669 CG MET A 281 29.282 98.396 17.527 1.00 62.41 C ATOM 1670 SD MET A 281 28.255 97.984 18.953 1.00 72.33 S ATOM 1671 CE MET A 281 29.346 98.455 20.294 1.00 70.94 C ATOM 1672 N LEU A 282 32.116 95.033 16.131 1.00 45.30 N ATOM 1673 CA LEU A 282 32.525 93.838 15.386 1.00 43.95 C ATOM 1674 C LEU A 282 33.117 92.759 16.288 1.00 44.11 C ATOM 1675 O LEU A 282 32.955 91.578 16.006 1.00 43.66 O ATOM 1676 CB LEU A 282 33.526 94.185 14.278 1.00 42.04 C ATOM 1677 CG LEU A 282 33.045 95.081 13.138 1.00 40.75 C ATOM 1678 CD1 LEU A 282 34.210 95.411 12.218 1.00 40.02 C ATOM 1679 CD2 LEU A 282 31.907 94.436 12.363 1.00 40.94 C ATOM 1680 N MET A 283 33.812 93.162 17.350 1.00 46.89 N ATOM 1681 CA MET A 283 34.345 92.208 18.330 1.00 49.64 C ATOM 1682 C MET A 283 33.224 91.528 19.120 1.00 47.52 C ATOM 1683 O MET A 283 33.314 90.336 19.409 1.00 44.65 O ATOM 1684 CB MET A 283 35.359 92.880 19.265 1.00 55.16 C ATOM 1685 CG MET A 283 36.698 93.162 18.592 1.00 59.76 C ATOM 1686 SD MET A 283 37.741 94.343 19.478 1.00 68.21 S ATOM 1687 CE MET A 283 39.259 94.244 18.525 1.00 65.97 C ATOM 1688 N ARG A 284 32.161 92.270 19.433 1.00 47.22 N ATOM 1689 CA ARG A 284 30.956 91.688 20.044 1.00 47.83 C ATOM 1690 C ARG A 284 30.241 90.706 19.097 1.00 46.26 C ATOM 1691 O ARG A 284 29.766 89.658 19.536 1.00 45.91 O ATOM 1692 CB ARG A 284 29.996 92.786 20.504 1.00 51.73 C ATOM 1693 CG ARG A 284 30.558 93.626 21.642 1.00 56.93 C ATOM 1694 CD ARG A 284 29.664 94.807 22.004 1.00 62.14 C ATOM 1695 NE ARG A 284 30.410 95.889 22.664 1.00 66.80 N ATOM 1696 CZ ARG A 284 29.866 96.966 23.238 1.00 68.96 C ATOM 1697 NH1 ARG A 284 28.545 97.146 23.261 1.00 71.12 N ATOM 1698 NH2 ARG A 284 30.655 97.880 23.798 1.00 70.42 N ATOM 1699 N GLU A 285 30.174 91.041 17.808 1.00 43.88 N ATOM 1700 CA GLU A 285 29.692 90.105 16.790 1.00 43.38 C ATOM 1701 C GLU A 285 30.536 88.823 16.766 1.00 42.48 C ATOM 1702 O GLU A 285 29.994 87.716 16.682 1.00 42.29 O ATOM 1703 CB GLU A 285 29.680 90.750 15.392 1.00 44.38 C ATOM 1704 CG GLU A 285 28.563 91.763 15.158 1.00 45.77 C ATOM 1705 CD GLU A 285 28.389 92.177 13.693 1.00 46.95 C ATOM 1706 OE1 GLU A 285 29.085 91.654 12.796 1.00 48.21 O ATOM 1707 OE2 GLU A 285 27.533 93.044 13.420 1.00 47.54 O ATOM 1708 N HIS A 286 31.856 88.982 16.856 1.00 40.33 N ATOM 1709 CA HIS A 286 32.787 87.851 16.779 1.00 39.56 C ATOM 1710 C HIS A 286 32.868 86.962 18.021 1.00 36.50 C ATOM 1711 O HIS A 286 33.299 85.814 17.909 1.00 35.89 O ATOM 1712 CB HIS A 286 34.188 88.332 16.387 1.00 41.76 C ATOM 1713 CG HIS A 286 34.251 88.931 15.016 1.00 44.13 C ATOM 1714 ND1 HIS A 286 35.309 89.703 14.585 1.00 45.37 N ATOM 1715 CD2 HIS A 286 33.370 88.894 13.990 1.00 45.14 C ATOM 1716 CE1 HIS A 286 35.086 90.098 13.346 1.00 45.90 C ATOM 1717 NE2 HIS A 286 33.915 89.623 12.961 1.00 46.70 N ATOM 1718 N LYS A 287 32.484 87.479 19.190 1.00 35.63 N ATOM 1719 CA LYS A 287 32.360 86.646 20.402 1.00 34.63 C ATOM 1720 C LYS A 287 31.226 85.640 20.230 1.00 32.15 C ATOM 1721 O LYS A 287 31.372 84.468 20.589 1.00 32.22 O ATOM 1722 CB LYS A 287 32.111 87.486 21.668 1.00 35.71 C ATOM 1723 CG LYS A 287 33.270 88.359 22.145 1.00 37.38 C ATOM 1724 CD LYS A 287 34.598 87.618 22.212 1.00 39.95 C ATOM 1725 CE LYS A 287 35.599 88.322 23.121 1.00 41.97 C ATOM 1726 NZ LYS A 287 36.956 87.708 23.028 1.00 43.33 N ATOM 1727 N ALA A 288 30.107 86.106 19.677 1.00 29.27 N ATOM 1728 CA ALA A 288 28.973 85.236 19.356 1.00 27.94 C ATOM 1729 C ALA A 288 29.330 84.198 18.294 1.00 27.06 C ATOM 1730 O ALA A 288 28.946 83.033 18.425 1.00 26.22 O ATOM 1731 CB ALA A 288 27.781 86.061 18.903 1.00 28.18 C ATOM 1732 N LEU A 289 30.060 84.617 17.254 1.00 26.44 N ATOM 1733 CA LEU A 289 30.543 83.682 16.219 1.00 26.61 C ATOM 1734 C LEU A 289 31.474 82.610 16.784 1.00 25.97 C ATOM 1735 O LEU A 289 31.424 81.454 16.363 1.00 24.49 O ATOM 1736 CB LEU A 289 31.252 84.422 15.072 1.00 26.73 C ATOM 1737 CG LEU A 289 30.376 85.184 14.065 1.00 26.65 C ATOM 1738 CD1 LEU A 289 31.253 85.815 12.998 1.00 26.58 C ATOM 1739 CD2 LEU A 289 29.326 84.288 13.424 1.00 26.49 C ATOM 1740 N LYS A 290 32.314 83.011 17.738 1.00 26.05 N ATOM 1741 CA LYS A 290 33.194 82.090 18.444 1.00 25.70 C ATOM 1742 C LYS A 290 32.445 80.994 19.212 1.00 23.86 C ATOM 1743 O LYS A 290 32.866 79.839 19.184 1.00 22.70 O ATOM 1744 CB LYS A 290 34.113 82.861 19.391 1.00 27.66 C ATOM 1745 CG LYS A 290 35.047 81.969 20.184 1.00 29.89 C ATOM 1746 CD LYS A 290 36.244 82.727 20.720 1.00 32.38 C ATOM 1747 CE LYS A 290 37.204 81.762 21.392 1.00 34.17 C ATOM 1748 NZ LYS A 290 38.214 82.459 22.220 1.00 35.91 N ATOM 1749 N THR A 291 31.365 81.353 19.908 1.00 22.49 N ATOM 1750 CA THR A 291 30.514 80.356 20.569 1.00 22.55 C ATOM 1751 C THR A 291 30.085 79.244 19.584 1.00 22.06 C ATOM 1752 O THR A 291 30.163 78.049 19.900 1.00 21.62 O ATOM 1753 CB THR A 291 29.253 81.003 21.204 1.00 22.97 C ATOM 1754 OG1 THR A 291 29.640 82.039 22.119 1.00 22.71 O ATOM 1755 CG2 THR A 291 28.405 79.964 21.952 1.00 22.68 C ATOM 1756 N LEU A 292 29.663 79.652 18.389 1.00 21.17 N ATOM 1757 CA LEU A 292 29.164 78.718 17.380 1.00 21.09 C ATOM 1758 C LEU A 292 30.250 77.784 16.868 1.00 20.65 C ATOM 1759 O LEU A 292 30.037 76.574 16.767 1.00 21.15 O ATOM 1760 CB LEU A 292 28.533 79.470 16.207 1.00 21.08 C ATOM 1761 CG LEU A 292 27.342 80.360 16.550 1.00 21.09 C ATOM 1762 CD1 LEU A 292 26.970 81.208 15.344 1.00 21.31 C ATOM 1763 CD2 LEU A 292 26.159 79.527 17.039 1.00 21.28 C ATOM 1764 N GLY A 293 31.411 78.343 16.556 1.00 20.30 N ATOM 1765 CA GLY A 293 32.571 77.544 16.169 1.00 20.06 C ATOM 1766 C GLY A 293 33.033 76.545 17.220 1.00 20.14 C ATOM 1767 O GLY A 293 33.504 75.456 16.865 1.00 20.45 O ATOM 1768 N ILE A 294 32.912 76.907 18.504 1.00 19.37 N ATOM 1769 CA ILE A 294 33.222 75.989 19.605 1.00 18.82 C ATOM 1770 C ILE A 294 32.243 74.816 19.588 1.00 18.51 C ATOM 1771 O ILE A 294 32.652 73.659 19.608 1.00 17.85 O ATOM 1772 CB ILE A 294 33.211 76.696 20.991 1.00 18.94 C ATOM 1773 CG1 ILE A 294 34.383 77.670 21.104 1.00 19.20 C ATOM 1774 CG2 ILE A 294 33.323 75.687 22.127 1.00 18.81 C ATOM 1775 CD1 ILE A 294 34.211 78.718 22.189 1.00 19.44 C ATOM 1776 N ILE A 295 30.950 75.126 19.542 1.00 19.30 N ATOM 1777 CA ILE A 295 29.899 74.099 19.403 1.00 19.11 C ATOM 1778 C ILE A 295 30.202 73.210 18.194 1.00 18.99 C ATOM 1779 O ILE A 295 30.114 71.983 18.274 1.00 18.34 O ATOM 1780 CB ILE A 295 28.489 74.737 19.296 1.00 19.24 C ATOM 1781 CG1 ILE A 295 28.064 75.309 20.658 1.00 19.58 C ATOM 1782 CG2 ILE A 295 27.449 73.733 18.800 1.00 19.23 C ATOM 1783 CD1 ILE A 295 26.960 76.353 20.574 1.00 20.06 C ATOM 1784 N MET A 296 30.592 73.834 17.085 1.00 19.52 N ATOM 1785 CA MET A 296 30.924 73.082 15.873 1.00 20.12 C ATOM 1786 C MET A 296 32.124 72.173 16.074 1.00 20.19 C ATOM 1787 O MET A 296 32.069 70.997 15.740 1.00 21.24 O ATOM 1788 CB MET A 296 31.149 74.028 14.694 1.00 20.35 C ATOM 1789 CG MET A 296 29.855 74.610 14.157 1.00 20.44 C ATOM 1790 SD MET A 296 30.117 75.906 12.938 1.00 21.40 S ATOM 1791 CE MET A 296 28.458 76.566 12.818 1.00 21.46 C ATOM 1792 N GLY A 297 33.192 72.718 16.643 1.00 20.54 N ATOM 1793 CA GLY A 297 34.405 71.955 16.913 1.00 20.41 C ATOM 1794 C GLY A 297 34.195 70.780 17.842 1.00 20.56 C ATOM 1795 O GLY A 297 34.690 69.680 17.578 1.00 20.46 O ATOM 1796 N VAL A 298 33.462 71.011 18.931 1.00 20.62 N ATOM 1797 CA VAL A 298 33.201 69.967 19.923 1.00 20.88 C ATOM 1798 C VAL A 298 32.308 68.863 19.351 1.00 20.72 C ATOM 1799 O VAL A 298 32.520 67.692 19.654 1.00 20.71 O ATOM 1800 CB VAL A 298 32.618 70.556 21.235 1.00 21.56 C ATOM 1801 CG1 VAL A 298 32.152 69.461 22.193 1.00 22.58 C ATOM 1802 CG2 VAL A 298 33.666 71.400 21.932 1.00 20.89 C ATOM 1803 N PHE A 299 31.325 69.232 18.526 1.00 20.88 N ATOM 1804 CA PHE A 299 30.453 68.254 17.862 1.00 20.18 C ATOM 1805 C PHE A 299 31.262 67.287 17.019 1.00 20.46 C ATOM 1806 O PHE A 299 31.000 66.075 17.034 1.00 20.96 O ATOM 1807 CB PHE A 299 29.410 68.963 16.992 1.00 20.44 C ATOM 1808 CG PHE A 299 28.389 68.043 16.387 1.00 19.96 C ATOM 1809 CD1 PHE A 299 27.228 67.716 17.083 1.00 20.43 C ATOM 1810 CD2 PHE A 299 28.585 67.498 15.128 1.00 19.95 C ATOM 1811 CE1 PHE A 299 26.271 66.866 16.528 1.00 20.65 C ATOM 1812 CE2 PHE A 299 27.644 66.641 14.568 1.00 20.39 C ATOM 1813 CZ PHE A 299 26.480 66.326 15.267 1.00 20.78 C ATOM 1814 N THR A 300 32.244 67.830 16.297 1.00 20.63 N ATOM 1815 CA THR A 300 33.169 67.045 15.471 1.00 21.55 C ATOM 1816 C THR A 300 34.007 66.069 16.304 1.00 22.83 C ATOM 1817 O THR A 300 34.091 64.880 15.983 1.00 22.96 O ATOM 1818 CB THR A 300 34.113 67.973 14.674 1.00 21.49 C ATOM 1819 OG1 THR A 300 33.335 68.890 13.890 1.00 21.53 O ATOM 1820 CG2 THR A 300 35.018 67.179 13.751 1.00 21.63 C ATOM 1821 N LEU A 301 34.626 66.576 17.370 1.00 24.11 N ATOM 1822 CA LEU A 301 35.375 65.732 18.296 1.00 24.60 C ATOM 1823 C LEU A 301 34.516 64.614 18.898 1.00 23.68 C ATOM 1824 O LEU A 301 34.989 63.486 19.068 1.00 23.17 O ATOM 1825 CB LEU A 301 35.989 66.569 19.428 1.00 26.25 C ATOM 1826 CG LEU A 301 37.173 67.477 19.081 1.00 28.45 C ATOM 1827 CD1 LEU A 301 37.733 68.086 20.356 1.00 29.30 C ATOM 1828 CD2 LEU A 301 38.274 66.732 18.337 1.00 29.34 C ATOM 1829 N CYS A 302 33.261 64.927 19.210 1.00 22.49 N ATOM 1830 CA CYS A 302 32.379 63.973 19.867 1.00 22.06 C ATOM 1831 C CYS A 302 31.881 62.875 18.930 1.00 21.25 C ATOM 1832 O CYS A 302 31.796 61.719 19.346 1.00 21.19 O ATOM 1833 CB CYS A 302 31.204 64.692 20.544 1.00 22.97 C ATOM 1834 SG CYS A 302 31.663 65.610 22.042 1.00 24.80 S ATOM 1835 N TRP A 303 31.575 63.219 17.675 1.00 20.42 N ATOM 1836 CA TRP A 303 30.923 62.280 16.750 1.00 19.78 C ATOM 1837 C TRP A 303 31.814 61.641 15.681 1.00 20.06 C ATOM 1838 O TRP A 303 31.552 60.504 15.282 1.00 19.26 O ATOM 1839 CB TRP A 303 29.703 62.947 16.089 1.00 19.53 C ATOM 1840 CG TRP A 303 28.487 62.966 16.994 1.00 18.57 C ATOM 1841 CD1 TRP A 303 27.887 64.060 17.535 1.00 18.14 C ATOM 1842 CD2 TRP A 303 27.746 61.829 17.461 1.00 17.91 C ATOM 1843 NE1 TRP A 303 26.815 63.680 18.305 1.00 17.92 N ATOM 1844 CE2 TRP A 303 26.706 62.316 18.278 1.00 17.64 C ATOM 1845 CE3 TRP A 303 27.859 60.443 17.260 1.00 17.62 C ATOM 1846 CZ2 TRP A 303 25.779 61.473 18.895 1.00 17.66 C ATOM 1847 CZ3 TRP A 303 26.939 59.600 17.881 1.00 17.59 C ATOM 1848 CH2 TRP A 303 25.916 60.119 18.695 1.00 17.59 C ATOM 1849 N LEU A 304 32.848 62.349 15.213 1.00 20.95 N ATOM 1850 CA LEU A 304 33.696 61.828 14.120 1.00 21.53 C ATOM 1851 C LEU A 304 34.392 60.501 14.456 1.00 21.66 C ATOM 1852 O LEU A 304 34.526 59.656 13.579 1.00 22.29 O ATOM 1853 CB LEU A 304 34.725 62.862 13.634 1.00 21.90 C ATOM 1854 CG LEU A 304 35.658 62.437 12.484 1.00 22.62 C ATOM 1855 CD1 LEU A 304 34.857 61.992 11.263 1.00 23.02 C ATOM 1856 CD2 LEU A 304 36.627 63.555 12.099 1.00 22.82 C ATOM 1857 N PRO A 305 34.836 60.311 15.714 1.00 21.45 N ATOM 1858 CA PRO A 305 35.373 58.991 16.059 1.00 21.38 C ATOM 1859 C PRO A 305 34.376 57.848 15.873 1.00 21.14 C ATOM 1860 O PRO A 305 34.731 56.842 15.272 1.00 20.60 O ATOM 1861 CB PRO A 305 35.770 59.141 17.532 1.00 21.73 C ATOM 1862 CG PRO A 305 36.077 60.590 17.672 1.00 21.93 C ATOM 1863 CD PRO A 305 35.116 61.305 16.764 1.00 21.55 C ATOM 1864 N PHE A 306 33.149 58.012 16.372 1.00 21.65 N ATOM 1865 CA PHE A 306 32.105 56.986 16.222 1.00 21.67 C ATOM 1866 C PHE A 306 31.851 56.639 14.755 1.00 21.33 C ATOM 1867 O PHE A 306 31.797 55.464 14.398 1.00 20.30 O ATOM 1868 CB PHE A 306 30.778 57.415 16.882 1.00 21.77 C ATOM 1869 CG PHE A 306 29.634 56.484 16.577 1.00 21.55 C ATOM 1870 CD1 PHE A 306 29.489 55.291 17.272 1.00 21.68 C ATOM 1871 CD2 PHE A 306 28.728 56.780 15.562 1.00 21.60 C ATOM 1872 CE1 PHE A 306 28.451 54.413 16.977 1.00 21.92 C ATOM 1873 CE2 PHE A 306 27.691 55.910 15.258 1.00 21.93 C ATOM 1874 CZ PHE A 306 27.551 54.721 15.966 1.00 22.11 C ATOM 1875 N PHE A 307 31.695 57.664 13.922 1.00 21.93 N ATOM 1876 CA PHE A 307 31.386 57.463 12.501 1.00 23.22 C ATOM 1877 C PHE A 307 32.546 56.837 11.704 1.00 24.85 C ATOM 1878 O PHE A 307 32.298 56.068 10.784 1.00 24.51 O ATOM 1879 CB PHE A 307 30.860 58.754 11.846 1.00 22.79 C ATOM 1880 CG PHE A 307 29.402 59.008 12.123 1.00 22.98 C ATOM 1881 CD1 PHE A 307 28.413 58.332 11.406 1.00 23.79 C ATOM 1882 CD2 PHE A 307 29.005 59.885 13.122 1.00 23.05 C ATOM 1883 CE1 PHE A 307 27.064 58.545 11.669 1.00 23.57 C ATOM 1884 CE2 PHE A 307 27.657 60.107 13.386 1.00 23.35 C ATOM 1885 CZ PHE A 307 26.686 59.435 12.662 1.00 23.33 C ATOM 1886 N LEU A 308 33.795 57.147 12.055 1.00 26.59 N ATOM 1887 CA LEU A 308 34.946 56.472 11.436 1.00 28.40 C ATOM 1888 C LEU A 308 34.993 54.996 11.859 1.00 29.89 C ATOM 1889 O LEU A 308 35.191 54.101 11.036 1.00 29.23 O ATOM 1890 CB LEU A 308 36.263 57.169 11.805 1.00 28.31 C ATOM 1891 CG LEU A 308 36.460 58.587 11.244 1.00 28.64 C ATOM 1892 CD1 LEU A 308 37.640 59.264 11.923 1.00 28.25 C ATOM 1893 CD2 LEU A 308 36.636 58.590 9.731 1.00 28.56 C ATOM 1894 N VAL A 309 34.803 54.765 13.151 1.00 31.29 N ATOM 1895 CA VAL A 309 34.784 53.417 13.720 1.00 33.39 C ATOM 1896 C VAL A 309 33.597 52.584 13.221 1.00 34.53 C ATOM 1897 O VAL A 309 33.731 51.378 13.029 1.00 36.06 O ATOM 1898 CB VAL A 309 34.856 53.490 15.273 1.00 34.10 C ATOM 1899 CG1 VAL A 309 34.047 52.403 15.967 1.00 34.88 C ATOM 1900 CG2 VAL A 309 36.311 53.457 15.711 1.00 34.36 C ATOM 1901 N ASN A 310 32.448 53.227 13.026 1.00 36.02 N ATOM 1902 CA ASN A 310 31.269 52.581 12.435 1.00 36.15 C ATOM 1903 C ASN A 310 31.555 51.994 11.044 1.00 36.12 C ATOM 1904 O ASN A 310 31.076 50.903 10.733 1.00 36.73 O ATOM 1905 CB ASN A 310 30.109 53.588 12.378 1.00 36.27 C ATOM 1906 CG ASN A 310 28.822 52.996 11.826 1.00 36.32 C ATOM 1907 OD1 ASN A 310 28.224 53.548 10.908 1.00 38.15 O ATOM 1908 ND2 ASN A 310 28.380 51.888 12.394 1.00 35.77 N ATOM 1909 N ILE A 311 32.348 52.700 10.232 1.00 35.64 N ATOM 1910 CA ILE A 311 32.746 52.213 8.898 1.00 35.85 C ATOM 1911 C ILE A 311 33.722 51.036 9.007 1.00 36.22 C ATOM 1912 O ILE A 311 33.533 50.002 8.365 1.00 35.69 O ATOM 1913 CB ILE A 311 33.378 53.331 8.030 1.00 35.62 C ATOM 1914 CG1 ILE A 311 32.382 54.482 7.789 1.00 35.20 C ATOM 1915 CG2 ILE A 311 33.862 52.778 6.692 1.00 35.98 C ATOM 1916 CD1 ILE A 311 31.054 54.084 7.179 1.00 35.15 C ATOM 1917 N VAL A 312 34.756 51.196 9.829 1.00 36.56 N ATOM 1918 CA VAL A 312 35.723 50.117 10.085 1.00 35.99 C ATOM 1919 C VAL A 312 34.991 48.846 10.563 1.00 36.21 C ATOM 1920 O VAL A 312 35.310 47.742 10.129 1.00 35.25 O ATOM 1921 CB VAL A 312 36.812 50.559 11.109 1.00 35.29 C ATOM 1922 CG1 VAL A 312 37.686 49.386 11.543 1.00 34.89 C ATOM 1923 CG2 VAL A 312 37.684 51.667 10.528 1.00 34.60 C ATOM 1924 N ASN A 313 33.997 49.016 11.433 1.00 37.70 N ATOM 1925 CA ASN A 313 33.276 47.887 12.021 1.00 39.28 C ATOM 1926 C ASN A 313 32.358 47.117 11.051 1.00 40.53 C ATOM 1927 O ASN A 313 32.187 45.905 11.211 1.00 39.73 O ATOM 1928 CB ASN A 313 32.481 48.351 13.244 1.00 40.12 C ATOM 1929 CG ASN A 313 31.980 47.194 14.087 1.00 40.65 C ATOM 1930 OD1 ASN A 313 32.768 46.403 14.612 1.00 41.20 O ATOM 1931 ND2 ASN A 313 30.665 47.083 14.218 1.00 42.93 N ATOM 1932 N VAL A 314 31.767 47.794 10.063 1.00 41.51 N ATOM 1933 CA VAL A 314 30.990 47.077 9.030 1.00 42.72 C ATOM 1934 C VAL A 314 31.861 46.269 8.063 1.00 42.68 C ATOM 1935 O VAL A 314 31.386 45.287 7.502 1.00 44.38 O ATOM 1936 CB VAL A 314 30.002 47.972 8.227 1.00 42.75 C ATOM 1937 CG1 VAL A 314 28.946 48.545 9.156 1.00 42.25 C ATOM 1938 CG2 VAL A 314 30.708 49.069 7.427 1.00 42.88 C ATOM 1939 N PHE A 315 33.111 46.682 7.856 1.00 43.58 N ATOM 1940 CA PHE A 315 34.037 45.925 6.998 1.00 44.94 C ATOM 1941 C PHE A 315 34.655 44.744 7.730 1.00 45.79 C ATOM 1942 O PHE A 315 34.861 43.685 7.133 1.00 47.32 O ATOM 1943 CB PHE A 315 35.130 46.829 6.415 1.00 45.05 C ATOM 1944 CG PHE A 315 34.623 47.755 5.355 1.00 46.32 C ATOM 1945 CD1 PHE A 315 34.064 47.239 4.194 1.00 48.38 C ATOM 1946 CD2 PHE A 315 34.673 49.134 5.514 1.00 47.51 C ATOM 1947 CE1 PHE A 315 33.570 48.073 3.210 1.00 48.55 C ATOM 1948 CE2 PHE A 315 34.180 49.978 4.528 1.00 48.19 C ATOM 1949 CZ PHE A 315 33.628 49.446 3.373 1.00 48.53 C ATOM 1950 N ASN A 316 34.947 44.930 9.016 1.00 44.86 N ATOM 1951 CA ASN A 316 35.514 43.874 9.846 1.00 42.19 C ATOM 1952 C ASN A 316 35.097 44.087 11.297 1.00 40.95 C ATOM 1953 O ASN A 316 35.508 45.061 11.928 1.00 41.56 O ATOM 1954 CB ASN A 316 37.039 43.889 9.706 1.00 42.00 C ATOM 1955 CG ASN A 316 37.694 42.619 10.212 1.00 41.96 C ATOM 1956 OD1 ASN A 316 37.081 41.805 10.905 1.00 41.28 O ATOM 1957 ND2 ASN A 316 38.962 42.448 9.868 1.00 42.22 N ATOM 1958 N ARG A 317 34.279 43.180 11.821 1.00 39.45 N ATOM 1959 CA ARG A 317 33.747 43.324 13.178 1.00 40.23 C ATOM 1960 C ARG A 317 34.812 43.118 14.270 1.00 38.73 C ATOM 1961 O ARG A 317 34.683 43.670 15.364 1.00 38.70 O ATOM 1962 CB ARG A 317 32.511 42.432 13.379 1.00 42.46 C ATOM 1963 CG ARG A 317 31.364 42.852 12.459 1.00 45.04 C ATOM 1964 CD ARG A 317 30.087 42.031 12.592 1.00 47.30 C ATOM 1965 NE ARG A 317 29.111 42.408 11.553 1.00 49.60 N ATOM 1966 CZ ARG A 317 28.032 41.701 11.196 1.00 50.53 C ATOM 1967 NH1 ARG A 317 27.730 40.540 11.780 1.00 51.86 N ATOM 1968 NH2 ARG A 317 27.237 42.165 10.236 1.00 52.12 N ATOM 1969 N ASP A 318 35.873 42.375 13.952 1.00 38.05 N ATOM 1970 CA ASP A 318 36.992 42.147 14.879 1.00 37.75 C ATOM 1971 C ASP A 318 37.903 43.361 15.080 1.00 36.98 C ATOM 1972 O ASP A 318 38.631 43.411 16.063 1.00 36.71 O ATOM 1973 CB ASP A 318 37.866 40.983 14.407 1.00 38.67 C ATOM 1974 CG ASP A 318 37.104 39.681 14.294 1.00 40.34 C ATOM 1975 OD1 ASP A 318 36.266 39.393 15.175 1.00 42.13 O ATOM 1976 OD2 ASP A 318 37.347 38.940 13.319 1.00 41.26 O ATOM 1977 N LEU A 319 37.888 44.314 14.150 1.00 37.30 N ATOM 1978 CA LEU A 319 38.698 45.532 14.280 1.00 37.57 C ATOM 1979 C LEU A 319 38.192 46.497 15.352 1.00 36.89 C ATOM 1980 O LEU A 319 38.957 47.332 15.820 1.00 36.79 O ATOM 1981 CB LEU A 319 38.812 46.270 12.935 1.00 38.42 C ATOM 1982 CG LEU A 319 39.776 45.682 11.895 1.00 39.00 C ATOM 1983 CD1 LEU A 319 39.717 46.492 10.609 1.00 38.88 C ATOM 1984 CD2 LEU A 319 41.204 45.639 12.425 1.00 39.10 C ATOM 1985 N VAL A 320 36.918 46.391 15.728 1.00 37.03 N ATOM 1986 CA VAL A 320 36.325 47.236 16.761 1.00 37.62 C ATOM 1987 C VAL A 320 35.506 46.359 17.718 1.00 37.26 C ATOM 1988 O VAL A 320 34.397 45.929 17.364 1.00 40.68 O ATOM 1989 CB VAL A 320 35.427 48.330 16.135 1.00 38.59 C ATOM 1990 CG1 VAL A 320 34.785 49.209 17.207 1.00 39.45 C ATOM 1991 CG2 VAL A 320 36.229 49.187 15.171 1.00 39.07 C ATOM 1992 N PRO A 321 36.034 46.099 18.934 1.00 35.68 N ATOM 1993 CA PRO A 321 35.232 45.391 19.933 1.00 35.71 C ATOM 1994 C PRO A 321 33.956 46.154 20.270 1.00 36.26 C ATOM 1995 O PRO A 321 33.952 47.388 20.256 1.00 37.78 O ATOM 1996 CB PRO A 321 36.151 45.317 21.160 1.00 35.60 C ATOM 1997 CG PRO A 321 37.524 45.554 20.649 1.00 35.94 C ATOM 1998 CD PRO A 321 37.391 46.406 19.427 1.00 35.85 C ATOM 1999 N ASP A 322 32.897 45.416 20.581 1.00 35.86 N ATOM 2000 CA ASP A 322 31.582 46.005 20.805 1.00 36.00 C ATOM 2001 C ASP A 322 31.593 47.015 21.940 1.00 34.92 C ATOM 2002 O ASP A 322 30.991 48.065 21.805 1.00 35.44 O ATOM 2003 CB ASP A 322 30.529 44.925 21.084 1.00 37.97 C ATOM 2004 CG ASP A 322 30.363 43.943 19.924 1.00 40.69 C ATOM 2005 OD1 ASP A 322 30.516 44.343 18.743 1.00 40.27 O ATOM 2006 OD2 ASP A 322 30.078 42.758 20.206 1.00 45.16 O ATOM 2007 N TRP A 323 32.278 46.709 23.043 1.00 34.12 N ATOM 2008 CA TRP A 323 32.341 47.634 24.189 1.00 33.69 C ATOM 2009 C TRP A 323 33.027 48.965 23.819 1.00 33.14 C ATOM 2010 O TRP A 323 32.645 50.028 24.319 1.00 32.61 O ATOM 2011 CB TRP A 323 33.009 46.976 25.413 1.00 34.09 C ATOM 2012 CG TRP A 323 34.498 46.781 25.309 1.00 34.65 C ATOM 2013 CD1 TRP A 323 35.156 45.648 24.911 1.00 35.40 C ATOM 2014 CD2 TRP A 323 35.513 47.747 25.615 1.00 34.76 C ATOM 2015 NE1 TRP A 323 36.519 45.852 24.947 1.00 35.35 N ATOM 2016 CE2 TRP A 323 36.765 47.131 25.373 1.00 34.95 C ATOM 2017 CE3 TRP A 323 35.486 49.076 26.064 1.00 34.17 C ATOM 2018 CZ2 TRP A 323 37.975 47.798 25.569 1.00 34.48 C ATOM 2019 CZ3 TRP A 323 36.695 49.740 26.259 1.00 34.04 C ATOM 2020 CH2 TRP A 323 37.920 49.099 26.008 1.00 34.39 C ATOM 2021 N LEU A 324 34.018 48.890 22.933 1.00 31.53 N ATOM 2022 CA LEU A 324 34.719 50.065 22.430 1.00 31.08 C ATOM 2023 C LEU A 324 33.833 50.886 21.495 1.00 30.25 C ATOM 2024 O LEU A 324 33.814 52.124 21.571 1.00 29.53 O ATOM 2025 CB LEU A 324 35.998 49.641 21.701 1.00 31.52 C ATOM 2026 CG LEU A 324 36.980 50.749 21.339 1.00 31.84 C ATOM 2027 CD1 LEU A 324 37.557 51.432 22.572 1.00 31.69 C ATOM 2028 CD2 LEU A 324 38.093 50.175 20.480 1.00 32.99 C ATOM 2029 N PHE A 325 33.126 50.187 20.607 1.00 28.70 N ATOM 2030 CA PHE A 325 32.050 50.775 19.796 1.00 28.15 C ATOM 2031 C PHE A 325 31.064 51.565 20.670 1.00 26.50 C ATOM 2032 O PHE A 325 30.732 52.717 20.359 1.00 25.57 O ATOM 2033 CB PHE A 325 31.322 49.662 19.023 1.00 29.20 C ATOM 2034 CG PHE A 325 30.214 50.143 18.125 1.00 30.04 C ATOM 2035 CD1 PHE A 325 30.483 50.508 16.813 1.00 30.35 C ATOM 2036 CD2 PHE A 325 28.890 50.198 18.580 1.00 30.17 C ATOM 2037 CE1 PHE A 325 29.464 50.935 15.973 1.00 30.85 C ATOM 2038 CE2 PHE A 325 27.866 50.629 17.744 1.00 30.38 C ATOM 2039 CZ PHE A 325 28.152 50.994 16.434 1.00 30.49 C ATOM 2040 N VAL A 326 30.630 50.951 21.769 1.00 24.93 N ATOM 2041 CA VAL A 326 29.702 51.591 22.707 1.00 25.00 C ATOM 2042 C VAL A 326 30.347 52.842 23.328 1.00 24.93 C ATOM 2043 O VAL A 326 29.715 53.892 23.379 1.00 24.77 O ATOM 2044 CB VAL A 326 29.215 50.606 23.807 1.00 25.56 C ATOM 2045 CG1 VAL A 326 28.327 51.302 24.826 1.00 25.84 C ATOM 2046 CG2 VAL A 326 28.441 49.436 23.201 1.00 25.56 C ATOM 2047 N ALA A 327 31.605 52.737 23.762 1.00 24.66 N ATOM 2048 CA ALA A 327 32.326 53.873 24.349 1.00 24.36 C ATOM 2049 C ALA A 327 32.355 55.064 23.396 1.00 24.74 C ATOM 2050 O ALA A 327 32.042 56.189 23.793 1.00 24.30 O ATOM 2051 CB ALA A 327 33.743 53.473 24.742 1.00 24.35 C ATOM 2052 N PHE A 328 32.724 54.811 22.139 1.00 25.63 N ATOM 2053 CA PHE A 328 32.658 55.838 21.089 1.00 25.79 C ATOM 2054 C PHE A 328 31.248 56.404 20.923 1.00 23.58 C ATOM 2055 O PHE A 328 31.089 57.617 20.749 1.00 22.17 O ATOM 2056 CB PHE A 328 33.141 55.299 19.738 1.00 28.08 C ATOM 2057 CG PHE A 328 34.630 55.108 19.651 1.00 30.97 C ATOM 2058 CD1 PHE A 328 35.481 56.192 19.736 1.00 33.61 C ATOM 2059 CD2 PHE A 328 35.183 53.849 19.451 1.00 33.08 C ATOM 2060 CE1 PHE A 328 36.855 56.024 19.651 1.00 34.66 C ATOM 2061 CE2 PHE A 328 36.558 53.682 19.366 1.00 33.79 C ATOM 2062 CZ PHE A 328 37.394 54.771 19.460 1.00 34.00 C ATOM 2063 N ASN A 329 30.234 55.539 20.972 1.00 21.87 N ATOM 2064 CA ASN A 329 28.848 56.017 20.936 1.00 21.59 C ATOM 2065 C ASN A 329 28.533 56.951 22.108 1.00 22.16 C ATOM 2066 O ASN A 329 27.879 57.971 21.893 1.00 22.44 O ATOM 2067 CB ASN A 329 27.817 54.874 20.879 1.00 20.71 C ATOM 2068 CG ASN A 329 26.515 55.256 20.151 1.00 20.25 C ATOM 2069 OD1 ASN A 329 25.853 54.385 19.598 1.00 19.90 O ATOM 2070 ND2 ASN A 329 26.133 56.532 20.158 1.00 20.22 N ATOM 2071 N TRP A 330 28.999 56.624 23.316 1.00 23.16 N ATOM 2072 CA TRP A 330 28.716 57.455 24.511 1.00 24.23 C ATOM 2073 C TRP A 330 29.446 58.793 24.510 1.00 23.27 C ATOM 2074 O TRP A 330 28.943 59.770 25.067 1.00 23.17 O ATOM 2075 CB TRP A 330 28.932 56.671 25.824 1.00 25.75 C ATOM 2076 CG TRP A 330 27.754 55.766 26.075 1.00 28.28 C ATOM 2077 CD1 TRP A 330 27.589 54.499 25.610 1.00 29.11 C ATOM 2078 CD2 TRP A 330 26.537 56.100 26.761 1.00 30.23 C ATOM 2079 NE1 TRP A 330 26.366 54.001 25.983 1.00 30.19 N ATOM 2080 CE2 TRP A 330 25.697 54.961 26.696 1.00 30.98 C ATOM 2081 CE3 TRP A 330 26.084 57.241 27.447 1.00 30.37 C ATOM 2082 CZ2 TRP A 330 24.428 54.926 27.288 1.00 30.85 C ATOM 2083 CZ3 TRP A 330 24.825 57.209 28.031 1.00 30.94 C ATOM 2084 CH2 TRP A 330 24.010 56.053 27.947 1.00 31.43 C ATOM 2085 N LEU A 331 30.609 58.846 23.869 1.00 22.37 N ATOM 2086 CA LEU A 331 31.257 60.122 23.562 1.00 21.68 C ATOM 2087 C LEU A 331 30.355 60.990 22.679 1.00 21.70 C ATOM 2088 O LEU A 331 30.313 62.208 22.842 1.00 22.46 O ATOM 2089 CB LEU A 331 32.612 59.883 22.891 1.00 21.38 C ATOM 2090 CG LEU A 331 33.439 61.082 22.447 1.00 21.20 C ATOM 2091 CD1 LEU A 331 33.725 62.030 23.596 1.00 21.65 C ATOM 2092 CD2 LEU A 331 34.736 60.588 21.833 1.00 21.35 C ATOM 2093 N GLY A 332 29.633 60.365 21.750 1.00 21.78 N ATOM 2094 CA GLY A 332 28.646 61.065 20.926 1.00 21.45 C ATOM 2095 C GLY A 332 27.485 61.625 21.723 1.00 21.15 C ATOM 2096 O GLY A 332 27.175 62.814 21.619 1.00 20.19 O ATOM 2097 N TYR A 333 26.847 60.764 22.515 1.00 21.69 N ATOM 2098 CA TYR A 333 25.749 61.176 23.413 1.00 22.66 C ATOM 2099 C TYR A 333 26.176 62.288 24.369 1.00 23.08 C ATOM 2100 O TYR A 333 25.396 63.203 24.623 1.00 24.26 O ATOM 2101 CB TYR A 333 25.213 59.999 24.246 1.00 22.72 C ATOM 2102 CG TYR A 333 24.545 58.855 23.487 1.00 23.04 C ATOM 2103 CD1 TYR A 333 23.926 59.037 22.235 1.00 23.35 C ATOM 2104 CD2 TYR A 333 24.503 57.582 24.051 1.00 23.54 C ATOM 2105 CE1 TYR A 333 23.316 57.969 21.574 1.00 23.21 C ATOM 2106 CE2 TYR A 333 23.896 56.518 23.402 1.00 23.66 C ATOM 2107 CZ TYR A 333 23.310 56.707 22.167 1.00 23.42 C ATOM 2108 OH TYR A 333 22.710 55.626 21.562 1.00 23.20 O ATOM 2109 N ALA A 334 27.411 62.201 24.880 1.00 23.28 N ATOM 2110 CA ALA A 334 28.023 63.239 25.736 1.00 23.36 C ATOM 2111 C ALA A 334 28.013 64.659 25.152 1.00 23.37 C ATOM 2112 O ALA A 334 27.975 65.632 25.899 1.00 23.10 O ATOM 2113 CB ALA A 334 29.451 62.846 26.096 1.00 23.22 C ATOM 2114 N ASN A 335 28.067 64.777 23.831 1.00 24.22 N ATOM 2115 CA ASN A 335 27.885 66.069 23.157 1.00 25.24 C ATOM 2116 C ASN A 335 26.603 66.794 23.580 1.00 25.96 C ATOM 2117 O ASN A 335 26.596 68.019 23.690 1.00 25.52 O ATOM 2118 CB ASN A 335 27.874 65.891 21.634 1.00 24.94 C ATOM 2119 CG ASN A 335 27.740 67.204 20.903 1.00 24.82 C ATOM 2120 OD1 ASN A 335 26.691 67.503 20.343 1.00 26.68 O ATOM 2121 ND2 ASN A 335 28.781 68.010 20.942 1.00 24.41 N ATOM 2122 N SER A 336 25.529 66.040 23.814 1.00 27.54 N ATOM 2123 CA SER A 336 24.268 66.622 24.289 1.00 29.54 C ATOM 2124 C SER A 336 24.377 67.316 25.657 1.00 30.44 C ATOM 2125 O SER A 336 23.628 68.247 25.930 1.00 31.91 O ATOM 2126 CB SER A 336 23.153 65.569 24.296 1.00 29.80 C ATOM 2127 OG SER A 336 22.875 65.130 22.970 1.00 30.30 O ATOM 2128 N ALA A 337 25.315 66.869 26.492 1.00 31.78 N ATOM 2129 CA ALA A 337 25.640 67.530 27.770 1.00 32.72 C ATOM 2130 C ALA A 337 26.551 68.758 27.648 1.00 33.58 C ATOM 2131 O ALA A 337 26.521 69.626 28.522 1.00 33.74 O ATOM 2132 CB ALA A 337 26.282 66.529 28.722 1.00 32.65 C ATOM 2133 N MET A 338 27.372 68.812 26.595 1.00 34.37 N ATOM 2134 CA MET A 338 28.402 69.850 26.437 1.00 34.50 C ATOM 2135 C MET A 338 27.871 71.224 26.046 1.00 32.88 C ATOM 2136 O MET A 338 28.379 72.236 26.528 1.00 31.27 O ATOM 2137 CB MET A 338 29.441 69.430 25.388 1.00 36.49 C ATOM 2138 CG MET A 338 30.250 68.190 25.746 1.00 38.57 C ATOM 2139 SD MET A 338 31.328 68.392 27.177 1.00 42.64 S ATOM 2140 CE MET A 338 32.545 69.535 26.522 1.00 43.76 C ATOM 2141 N ASN A 339 26.879 71.267 25.160 1.00 32.87 N ATOM 2142 CA ASN A 339 26.421 72.540 24.583 1.00 32.90 C ATOM 2143 C ASN A 339 25.884 73.574 25.570 1.00 30.88 C ATOM 2144 O ASN A 339 26.241 74.744 25.452 1.00 30.24 O ATOM 2145 CB ASN A 339 25.404 72.307 23.458 1.00 34.85 C ATOM 2146 CG ASN A 339 26.039 71.758 22.200 1.00 36.97 C ATOM 2147 OD1 ASN A 339 27.256 71.581 22.124 1.00 36.75 O ATOM 2148 ND2 ASN A 339 25.212 71.491 21.195 1.00 39.99 N ATOM 2149 N PRO A 340 25.036 73.158 26.534 1.00 29.98 N ATOM 2150 CA PRO A 340 24.595 74.101 27.567 1.00 30.23 C ATOM 2151 C PRO A 340 25.746 74.650 28.395 1.00 29.88 C ATOM 2152 O PRO A 340 25.739 75.830 28.743 1.00 29.60 O ATOM 2153 CB PRO A 340 23.657 73.263 28.459 1.00 30.45 C ATOM 2154 CG PRO A 340 23.328 72.042 27.677 1.00 30.62 C ATOM 2155 CD PRO A 340 24.486 71.808 26.757 1.00 30.50 C ATOM 2156 N ILE A 341 26.729 73.799 28.686 1.00 30.69 N ATOM 2157 CA ILE A 341 27.911 74.203 29.459 1.00 31.15 C ATOM 2158 C ILE A 341 28.740 75.207 28.654 1.00 31.17 C ATOM 2159 O ILE A 341 29.216 76.194 29.217 1.00 32.73 O ATOM 2160 CB ILE A 341 28.776 72.993 29.894 1.00 31.63 C ATOM 2161 CG1 ILE A 341 27.949 72.020 30.752 1.00 32.20 C ATOM 2162 CG2 ILE A 341 29.988 73.453 30.699 1.00 32.18 C ATOM 2163 CD1 ILE A 341 28.667 70.738 31.132 1.00 32.59 C ATOM 2164 N ILE A 342 28.897 74.959 27.349 1.00 30.17 N ATOM 2165 CA ILE A 342 29.595 75.886 26.446 1.00 29.60 C ATOM 2166 C ILE A 342 28.842 77.203 26.326 1.00 31.51 C ATOM 2167 O ILE A 342 29.452 78.269 26.357 1.00 30.52 O ATOM 2168 CB ILE A 342 29.801 75.278 25.035 1.00 28.40 C ATOM 2169 CG1 ILE A 342 30.847 74.154 25.096 1.00 28.05 C ATOM 2170 CG2 ILE A 342 30.235 76.339 24.019 1.00 27.64 C ATOM 2171 CD1 ILE A 342 30.782 73.169 23.948 1.00 27.25 C ATOM 2172 N LEU A 343 27.525 77.121 26.157 1.00 34.98 N ATOM 2173 CA LEU A 343 26.672 78.317 26.077 1.00 37.88 C ATOM 2174 C LEU A 343 26.688 79.130 27.376 1.00 40.53 C ATOM 2175 O LEU A 343 26.580 80.350 27.332 1.00 41.51 O ATOM 2176 CB LEU A 343 25.235 77.947 25.685 1.00 38.02 C ATOM 2177 CG LEU A 343 25.054 77.505 24.224 1.00 37.88 C ATOM 2178 CD1 LEU A 343 23.752 76.737 24.047 1.00 38.16 C ATOM 2179 CD2 LEU A 343 25.111 78.691 23.270 1.00 37.32 C ATOM 2180 N CYS A 344 26.866 78.455 28.510 1.00 43.49 N ATOM 2181 CA CYS A 344 27.035 79.116 29.815 1.00 47.77 C ATOM 2182 C CYS A 344 28.187 80.130 29.869 1.00 48.59 C ATOM 2183 O CYS A 344 28.081 81.121 30.585 1.00 50.27 O ATOM 2184 CB CYS A 344 27.207 78.067 30.929 1.00 50.78 C ATOM 2185 SG CYS A 344 26.708 78.602 32.581 1.00 55.80 S ATOM 2186 N ARG A 345 29.270 79.888 29.126 1.00 48.79 N ATOM 2187 CA ARG A 345 30.437 80.794 29.107 1.00 48.30 C ATOM 2188 C ARG A 345 30.329 81.951 28.109 1.00 49.01 C ATOM 2189 O ARG A 345 31.172 82.850 28.132 1.00 49.30 O ATOM 2190 CB ARG A 345 31.727 80.019 28.815 1.00 49.53 C ATOM 2191 CG ARG A 345 32.096 78.954 29.836 1.00 50.48 C ATOM 2192 CD ARG A 345 32.530 79.538 31.170 1.00 50.08 C ATOM 2193 NE ARG A 345 32.819 78.474 32.136 1.00 50.38 N ATOM 2194 CZ ARG A 345 34.012 77.918 32.369 1.00 49.78 C ATOM 2195 NH1 ARG A 345 35.108 78.305 31.721 1.00 50.73 N ATOM 2196 NH2 ARG A 345 34.114 76.953 33.279 1.00 49.65 N ATOM 2197 N SER A 346 29.339 81.924 27.216 1.00 50.42 N ATOM 2198 CA SER A 346 28.994 83.111 26.430 1.00 53.69 C ATOM 2199 C SER A 346 28.430 84.164 27.383 1.00 57.28 C ATOM 2200 O SER A 346 27.697 83.808 28.313 1.00 59.77 O ATOM 2201 CB SER A 346 27.957 82.777 25.366 1.00 54.89 C ATOM 2202 OG SER A 346 28.402 81.703 24.563 1.00 56.57 O ATOM 2203 N PRO A 347 28.762 85.454 27.167 1.00 61.16 N ATOM 2204 CA PRO A 347 28.406 86.513 28.140 1.00 63.37 C ATOM 2205 C PRO A 347 26.892 86.698 28.378 1.00 63.28 C ATOM 2206 O PRO A 347 26.436 86.674 29.526 1.00 61.06 O ATOM 2207 CB PRO A 347 29.028 87.785 27.535 1.00 63.80 C ATOM 2208 CG PRO A 347 29.265 87.479 26.093 1.00 63.45 C ATOM 2209 CD PRO A 347 29.440 85.995 25.973 1.00 62.27 C ATOM 2210 N ASP A 348 26.143 86.870 27.291 1.00 64.37 N ATOM 2211 CA ASP A 348 24.680 87.064 27.334 1.00 64.13 C ATOM 2212 C ASP A 348 23.918 85.880 27.939 1.00 62.17 C ATOM 2213 O ASP A 348 23.002 86.076 28.740 1.00 64.87 O ATOM 2214 CB ASP A 348 24.120 87.410 25.936 1.00 66.18 C ATOM 2215 CG ASP A 348 24.693 86.532 24.818 1.00 69.08 C ATOM 2216 OD1 ASP A 348 25.453 85.584 25.113 1.00 71.46 O ATOM 2217 OD2 ASP A 348 24.396 86.802 23.636 1.00 72.76 O ATOM 2218 N PHE A 349 24.301 84.664 27.559 1.00 60.64 N ATOM 2219 CA PHE A 349 23.706 83.442 28.124 1.00 59.05 C ATOM 2220 C PHE A 349 24.007 83.258 29.617 1.00 60.54 C ATOM 2221 O PHE A 349 23.178 82.708 30.348 1.00 60.29 O ATOM 2222 CB PHE A 349 24.190 82.201 27.367 1.00 57.96 C ATOM 2223 CG PHE A 349 23.375 81.859 26.152 1.00 56.16 C ATOM 2224 CD1 PHE A 349 23.685 82.407 24.910 1.00 55.55 C ATOM 2225 CD2 PHE A 349 22.319 80.958 26.241 1.00 54.99 C ATOM 2226 CE1 PHE A 349 22.947 82.073 23.783 1.00 55.35 C ATOM 2227 CE2 PHE A 349 21.577 80.621 25.120 1.00 54.95 C ATOM 2228 CZ PHE A 349 21.891 81.180 23.889 1.00 55.81 C ATOM 2229 N ARG A 350 25.189 83.697 30.059 1.00 62.51 N ATOM 2230 CA ARG A 350 25.586 83.575 31.470 1.00 65.40 C ATOM 2231 C ARG A 350 24.688 84.417 32.369 1.00 67.46 C ATOM 2232 O ARG A 350 24.188 83.919 33.380 1.00 68.95 O ATOM 2233 CB ARG A 350 27.051 83.981 31.682 1.00 66.31 C ATOM 2234 CG ARG A 350 27.639 83.496 33.001 1.00 66.33 C ATOM 2235 CD ARG A 350 29.158 83.622 33.022 1.00 67.71 C ATOM 2236 NE ARG A 350 29.785 82.778 34.044 1.00 69.58 N ATOM 2237 CZ ARG A 350 29.930 81.451 33.976 1.00 70.49 C ATOM 2238 NH1 ARG A 350 29.480 80.754 32.934 1.00 71.26 N ATOM 2239 NH2 ARG A 350 30.525 80.803 34.971 1.00 73.62 N ATOM 2240 N LYS A 351 24.487 85.681 31.985 1.00 67.88 N ATOM 2241 CA LYS A 351 23.559 86.589 32.679 1.00 69.80 C ATOM 2242 C LYS A 351 22.166 85.969 32.809 1.00 68.58 C ATOM 2243 O LYS A 351 21.576 85.977 33.892 1.00 68.34 O ATOM 2244 CB LYS A 351 23.441 87.928 31.936 1.00 72.05 C ATOM 2245 CG LYS A 351 24.684 88.804 31.995 1.00 74.36 C ATOM 2246 CD LYS A 351 24.622 89.928 30.968 1.00 75.88 C ATOM 2247 CE LYS A 351 25.983 90.572 30.746 1.00 75.95 C ATOM 2248 NZ LYS A 351 26.879 89.748 29.888 1.00 75.31 N ATOM 2249 N ALA A 352 21.667 85.425 31.697 1.00 66.57 N ATOM 2250 CA ALA A 352 20.339 84.807 31.634 1.00 64.83 C ATOM 2251 C ALA A 352 20.186 83.605 32.565 1.00 64.76 C ATOM 2252 O ALA A 352 19.144 83.460 33.201 1.00 63.77 O ATOM 2253 CB ALA A 352 20.010 84.408 30.203 1.00 64.94 C ATOM 2254 N PHE A 353 21.213 82.752 32.641 1.00 66.51 N ATOM 2255 CA PHE A 353 21.221 81.629 33.600 1.00 67.84 C ATOM 2256 C PHE A 353 21.302 82.119 35.054 1.00 66.44 C ATOM 2257 O PHE A 353 20.719 81.502 35.949 1.00 63.39 O ATOM 2258 CB PHE A 353 22.375 80.639 33.326 1.00 69.42 C ATOM 2259 CG PHE A 353 22.329 79.960 31.969 1.00 69.31 C ATOM 2260 CD1 PHE A 353 21.125 79.670 31.325 1.00 69.70 C ATOM 2261 CD2 PHE A 353 23.514 79.567 31.350 1.00 69.63 C ATOM 2262 CE1 PHE A 353 21.118 79.037 30.089 1.00 69.59 C ATOM 2263 CE2 PHE A 353 23.502 78.931 30.114 1.00 68.77 C ATOM 2264 CZ PHE A 353 22.305 78.667 29.485 1.00 67.98 C ATOM 2265 N LYS A 354 22.035 83.213 35.280 1.00 66.82 N ATOM 2266 CA LYS A 354 22.049 83.895 36.577 1.00 66.96 C ATOM 2267 C LYS A 354 20.729 84.633 36.794 1.00 65.32 C ATOM 2268 O LYS A 354 19.855 84.160 37.518 1.00 64.98 O ATOM 2269 CB LYS A 354 23.214 84.889 36.669 1.00 66.95 C ATOM 2270 CG LYS A 354 24.593 84.246 36.683 1.00 68.04 C ATOM 2271 CD LYS A 354 25.702 85.276 36.874 1.00 69.50 C ATOM 2272 CE LYS A 354 25.844 86.208 35.678 1.00 69.79 C ATOM 2273 NZ LYS A 354 27.106 86.999 35.727 1.00 69.84 N TER 2274 LYS A 354 HETATM 2275 NA NA A 401 16.177 42.380 17.781 1.00 45.23 NA HETATM 2276 NA NA A 402 22.732 66.620 19.169 1.00 48.23 NA HETATM 2277 N3 XTK A 501 25.211 52.119 9.997 1.00 18.68 N HETATM 2278 C16 XTK A 501 24.893 53.120 10.505 1.00 18.53 C HETATM 2279 C1 XTK A 501 24.536 54.295 11.033 1.00 18.29 C HETATM 2280 N1 XTK A 501 23.902 55.253 10.328 1.00 18.40 N HETATM 2281 C8 XTK A 501 23.669 56.297 11.158 1.00 18.31 C HETATM 2282 C7 XTK A 501 23.026 57.624 11.006 1.00 18.47 C HETATM 2283 C6 XTK A 501 22.933 58.488 12.091 1.00 18.45 C HETATM 2284 C5 XTK A 501 23.429 58.144 13.349 1.00 18.40 C HETATM 2285 C2 XTK A 501 24.752 54.611 12.363 1.00 18.44 C HETATM 2286 C3 XTK A 501 24.197 55.921 12.485 1.00 18.32 C HETATM 2287 C4 XTK A 501 24.050 56.906 13.594 1.00 18.23 C HETATM 2288 O1 XTK A 501 24.545 56.565 14.825 1.00 18.11 O HETATM 2289 C9 XTK A 501 24.206 57.254 16.029 1.00 18.09 C HETATM 2290 C10 XTK A 501 24.384 56.340 17.224 1.00 18.29 C HETATM 2291 O2 XTK A 501 24.023 57.083 18.391 1.00 17.53 O HETATM 2292 C11 XTK A 501 23.523 55.088 17.041 1.00 18.51 C HETATM 2293 N2 XTK A 501 23.428 54.333 18.275 1.00 18.81 N HETATM 2294 C12 XTK A 501 22.972 52.948 18.314 1.00 19.05 C HETATM 2295 C15 XTK A 501 24.067 52.063 17.704 1.00 19.15 C HETATM 2296 C14 XTK A 501 22.683 52.556 19.766 1.00 19.14 C HETATM 2297 C13 XTK A 501 21.663 52.839 17.533 1.00 19.48 C HETATM 2298 C17 XTK A 501 22.474 58.006 9.670 1.00 18.94 C HETATM 2299 N1 MHA A 801 7.762 40.377 22.346 1.00 37.23 N HETATM 2300 C1 MHA A 801 8.013 40.131 20.895 1.00 37.26 C HETATM 2301 C2 MHA A 801 8.574 41.277 20.060 1.00 37.91 C HETATM 2302 O1 MHA A 801 9.004 42.323 20.593 1.00 37.15 O HETATM 2303 O2 MHA A 801 8.601 41.130 18.817 1.00 37.26 O HETATM 2304 C3 MHA A 801 8.989 40.538 23.161 1.00 38.51 C HETATM 2305 C4 MHA A 801 9.569 39.195 23.561 1.00 39.47 C HETATM 2306 O3 MHA A 801 10.476 39.194 24.413 1.00 40.35 O HETATM 2307 O4 MHA A 801 9.158 38.132 23.048 1.00 40.63 O HETATM 2308 C5 MHA A 801 6.805 41.474 22.583 1.00 37.74 C HETATM 2309 C6 MHA A 801 5.973 41.328 23.849 1.00 39.21 C HETATM 2310 O5 MHA A 801 5.107 42.160 24.072 1.00 40.11 O HETATM 2311 N2 MHA A 801 6.176 40.325 24.716 1.00 39.95 N HETATM 2312 C18 OLC A2001 43.534 89.951 16.078 1.00 69.01 C HETATM 2313 C10 OLC A2001 36.416 85.017 15.409 1.00 56.63 C HETATM 2314 C9 OLC A2001 35.197 84.091 15.365 1.00 54.26 C HETATM 2315 C17 OLC A2001 42.763 88.750 16.618 1.00 69.09 C HETATM 2316 C11 OLC A2001 36.641 85.435 16.850 1.00 60.02 C HETATM 2317 C8 OLC A2001 35.081 83.286 14.074 1.00 50.38 C HETATM 2318 C16 OLC A2001 41.344 89.133 17.045 1.00 69.43 C HETATM 2319 C12 OLC A2001 37.289 86.542 17.222 1.00 64.10 C HETATM 2320 C7 OLC A2001 34.613 81.854 14.334 1.00 47.97 C HETATM 2321 C15 OLC A2001 40.317 88.149 16.490 1.00 69.83 C HETATM 2322 C13 OLC A2001 37.887 87.522 16.234 1.00 66.53 C HETATM 2323 C6 OLC A2001 33.760 81.323 13.192 1.00 45.99 C HETATM 2324 C14 OLC A2001 38.882 88.465 16.921 1.00 68.15 C HETATM 2325 C5 OLC A2001 33.178 79.955 13.521 1.00 43.95 C HETATM 2326 C4 OLC A2001 32.113 79.560 12.503 1.00 44.01 C HETATM 2327 C3 OLC A2001 30.748 80.145 12.804 1.00 43.21 C HETATM 2328 C18 OLC A2002 39.707 69.912 15.818 1.00 56.36 C HETATM 2329 C10 OLC A2002 36.046 76.590 13.184 1.00 56.73 C HETATM 2330 C9 OLC A2002 36.765 77.499 13.865 1.00 58.63 C HETATM 2331 C17 OLC A2002 38.325 70.443 15.481 1.00 55.64 C HETATM 2332 C11 OLC A2002 35.448 75.340 13.797 1.00 55.57 C HETATM 2333 C8 OLC A2002 37.105 77.427 15.346 1.00 58.52 C HETATM 2334 C24 OLC A2002 40.758 85.261 22.932 1.00 79.93 C HETATM 2335 C16 OLC A2002 38.103 70.483 13.972 1.00 54.54 C HETATM 2336 C12 OLC A2002 35.096 74.319 12.712 1.00 53.76 C HETATM 2337 C7 OLC A2002 36.204 78.349 16.163 1.00 58.70 C HETATM 2338 C15 OLC A2002 36.674 70.886 13.604 1.00 53.89 C HETATM 2339 C13 OLC A2002 35.121 72.880 13.229 1.00 52.58 C HETATM 2340 C6 OLC A2002 36.966 79.101 17.244 1.00 58.64 C HETATM 2341 C14 OLC A2002 36.540 72.402 13.539 1.00 53.20 C HETATM 2342 C5 OLC A2002 37.750 80.289 16.691 1.00 60.72 C HETATM 2343 C4 OLC A2002 38.207 81.172 17.843 1.00 63.18 C HETATM 2344 C3 OLC A2002 39.017 82.392 17.417 1.00 66.16 C HETATM 2345 C2 OLC A2002 39.174 83.325 18.621 1.00 68.99 C HETATM 2346 C21 OLC A2002 41.378 83.745 21.037 1.00 76.30 C HETATM 2347 C1 OLC A2002 40.524 83.995 18.651 1.00 72.43 C HETATM 2348 C22 OLC A2002 40.738 85.082 21.416 1.00 79.09 C HETATM 2349 O19 OLC A2002 40.775 84.889 17.865 1.00 76.22 O HETATM 2350 O25 OLC A2002 40.079 86.470 23.296 1.00 81.10 O HETATM 2351 O23 OLC A2002 41.465 86.148 20.792 1.00 82.79 O HETATM 2352 O20 OLC A2002 41.540 83.598 19.621 1.00 74.89 O HETATM 2353 C18 OLC A2003 20.382 80.474 0.381 0.50 47.03 C HETATM 2354 C10 OLC A2003 28.798 78.560 1.024 0.50 49.81 C HETATM 2355 C9 OLC A2003 29.725 79.196 -0.008 0.50 50.85 C HETATM 2356 C17 OLC A2003 21.094 79.284 -0.254 0.50 46.99 C HETATM 2357 C11 OLC A2003 27.412 79.194 0.993 0.50 48.99 C HETATM 2358 C8 OLC A2003 31.089 79.519 0.595 0.50 51.51 C HETATM 2359 C16 OLC A2003 22.520 79.647 -0.657 0.50 46.95 C HETATM 2360 C12 OLC A2003 27.003 79.473 -0.433 0.50 48.24 C HETATM 2361 C7 OLC A2003 32.204 79.324 -0.427 0.50 52.10 C HETATM 2362 C15 OLC A2003 23.432 78.425 -0.594 0.50 47.29 C HETATM 2363 C13 OLC A2003 25.752 79.256 -0.826 0.50 47.63 C HETATM 2364 C6 OLC A2003 32.860 80.652 -0.791 0.50 52.24 C HETATM 2365 C14 OLC A2003 24.728 78.729 0.149 0.50 47.39 C HETATM 2366 C10 OLC A2004 27.965 87.950 13.489 1.00 48.05 C HETATM 2367 C9 OLC A2004 28.011 88.637 12.332 1.00 51.01 C HETATM 2368 C11 OLC A2004 26.749 87.186 13.933 1.00 45.33 C HETATM 2369 C8 OLC A2004 26.877 88.780 11.325 1.00 51.89 C HETATM 2370 C24 OLC A2004 16.560 89.060 15.209 1.00 68.58 C HETATM 2371 C12 OLC A2004 26.707 86.778 15.397 1.00 44.67 C HETATM 2372 C7 OLC A2004 26.408 90.243 11.290 1.00 53.42 C HETATM 2373 C13 OLC A2004 25.249 86.561 15.793 1.00 44.90 C HETATM 2374 C6 OLC A2004 25.028 90.461 10.660 1.00 55.56 C HETATM 2375 C14 OLC A2004 25.095 85.537 16.905 1.00 45.82 C HETATM 2376 C5 OLC A2004 23.974 89.663 11.420 1.00 56.79 C HETATM 2377 C4 OLC A2004 22.554 90.213 11.426 1.00 57.63 C HETATM 2378 C3 OLC A2004 21.601 89.151 11.981 1.00 60.31 C HETATM 2379 C2 OLC A2004 21.888 88.755 13.435 1.00 64.19 C HETATM 2380 C21 OLC A2004 18.947 89.084 14.469 1.00 68.65 C HETATM 2381 C1 OLC A2004 20.930 87.674 13.885 1.00 67.07 C HETATM 2382 C22 OLC A2004 17.497 89.278 14.029 1.00 69.46 C HETATM 2383 O19 OLC A2004 21.348 86.594 14.291 1.00 66.09 O HETATM 2384 O25 OLC A2004 15.216 89.374 14.833 1.00 67.79 O HETATM 2385 O23 OLC A2004 17.310 90.599 13.502 1.00 71.35 O HETATM 2386 O20 OLC A2004 19.495 87.923 13.843 1.00 68.15 O HETATM 2387 C18 OLC A2005 16.478 58.302 1.001 1.00 48.53 C HETATM 2388 C10 OLC A2005 21.068 51.469 1.221 1.00 49.03 C HETATM 2389 C9 OLC A2005 20.990 50.172 0.926 1.00 49.64 C HETATM 2390 C17 OLC A2005 17.048 57.493 2.144 1.00 48.04 C HETATM 2391 C11 OLC A2005 19.867 52.385 1.236 1.00 47.73 C HETATM 2392 C8 OLC A2005 19.690 49.495 0.580 1.00 51.04 C HETATM 2393 C24 OLC A2005 27.831 42.538 4.369 1.00 58.39 C HETATM 2394 C16 OLC A2005 18.577 57.473 2.114 1.00 48.35 C HETATM 2395 C12 OLC A2005 20.052 53.465 2.297 1.00 48.55 C HETATM 2396 C7 OLC A2005 19.958 48.069 0.136 1.00 52.61 C HETATM 2397 C15 OLC A2005 19.141 56.475 3.131 1.00 48.66 C HETATM 2398 C13 OLC A2005 20.368 54.811 1.662 1.00 48.54 C HETATM 2399 C6 OLC A2005 20.153 47.139 1.327 1.00 53.23 C HETATM 2400 C14 OLC A2005 20.494 55.906 2.717 1.00 48.21 C HETATM 2401 C5 OLC A2005 20.603 45.751 0.899 1.00 55.31 C HETATM 2402 C4 OLC A2005 21.974 45.821 0.244 1.00 56.94 C HETATM 2403 C3 OLC A2005 22.914 44.719 0.705 1.00 58.01 C HETATM 2404 C2 OLC A2005 24.317 45.161 0.345 1.00 58.28 C HETATM 2405 C21 OLC A2005 27.168 44.283 2.758 1.00 54.86 C HETATM 2406 C1 OLC A2005 25.334 44.229 0.930 1.00 59.71 C HETATM 2407 C22 OLC A2005 26.878 42.874 3.219 1.00 57.02 C HETATM 2408 O19 OLC A2005 25.290 43.027 0.716 1.00 62.32 O HETATM 2409 O25 OLC A2005 28.016 43.579 5.340 1.00 59.41 O HETATM 2410 O23 OLC A2005 25.516 42.754 3.651 1.00 57.79 O HETATM 2411 O20 OLC A2005 26.359 44.864 1.742 1.00 54.58 O HETATM 2412 O HOH A3001 22.206 72.679 22.785 1.00 43.86 O HETATM 2413 O HOH A3002 23.064 81.015 12.493 1.00 51.34 O HETATM 2414 O HOH A3003 21.140 65.298 19.682 1.00 37.05 O HETATM 2415 O HOH A3004 24.039 68.796 19.557 1.00 52.53 O HETATM 2416 O HOH A3005 17.250 47.493 27.865 1.00 29.09 O HETATM 2417 O HOH A3006 12.981 43.070 24.605 1.00 24.78 O HETATM 2418 O HOH A3007 8.419 47.223 21.714 1.00 20.38 O HETATM 2419 O HOH A3008 7.531 44.676 20.696 1.00 27.26 O HETATM 2420 O HOH A3009 14.863 44.077 19.396 1.00 33.78 O HETATM 2421 O HOH A3010 21.405 60.620 19.151 1.00 34.52 O HETATM 2422 O HOH A3011 18.204 55.612 8.277 1.00 37.42 O HETATM 2423 O HOH A3012 20.033 57.694 6.618 1.00 54.71 O HETATM 2424 O HOH A3013 14.018 44.368 15.458 1.00 45.52 O HETATM 2425 O HOH A3014 16.651 43.737 15.986 1.00 32.73 O HETATM 2426 O HOH A3015 13.975 41.906 17.180 1.00 45.06 O HETATM 2427 O HOH A3016 21.349 44.519 22.246 1.00 35.60 O HETATM 2428 O HOH A3017 18.582 45.681 15.919 1.00 33.38 O HETATM 2429 O HOH A3018 29.559 55.522 9.799 1.00 34.23 O HETATM 2430 O HOH A3019 31.418 90.011 11.857 1.00 60.80 O HETATM 2431 O HOH A3020 28.907 70.710 20.206 1.00 27.56 O HETATM 2432 O HOH A3021 32.624 59.180 19.078 1.00 20.20 O HETATM 2433 O HOH A3022 24.828 65.658 19.401 1.00 42.25 O HETATM 2434 O HOH A3023 24.495 63.646 21.319 1.00 25.93 O HETATM 2435 O HOH A3024 26.108 70.508 18.628 1.00 49.66 O HETATM 2436 O HOH A3025 22.821 63.158 18.940 1.00 24.14 O HETATM 2437 O HOH A3026 5.238 44.191 22.321 1.00 25.96 O CONECT 380 2276 CONECT 586 1272 CONECT 692 2276 CONECT 1218 2275 CONECT 1220 1266 CONECT 1245 2275 CONECT 1264 2275 CONECT 1266 1220 CONECT 1272 586 CONECT 2275 1218 1245 1264 2420 CONECT 2275 2425 2426 CONECT 2276 380 692 2414 2415 CONECT 2276 2433 CONECT 2277 2278 CONECT 2278 2277 2279 CONECT 2279 2278 2280 2285 CONECT 2280 2279 2281 CONECT 2281 2280 2282 2286 CONECT 2282 2281 2283 2298 CONECT 2283 2282 2284 CONECT 2284 2283 2287 CONECT 2285 2279 2286 CONECT 2286 2281 2285 2287 CONECT 2287 2284 2286 2288 CONECT 2288 2287 2289 CONECT 2289 2288 2290 CONECT 2290 2289 2291 2292 CONECT 2291 2290 CONECT 2292 2290 2293 CONECT 2293 2292 2294 CONECT 2294 2293 2295 2296 2297 CONECT 2295 2294 CONECT 2296 2294 CONECT 2297 2294 CONECT 2298 2282 CONECT 2299 2300 2304 2308 CONECT 2300 2299 2301 CONECT 2301 2300 2302 2303 CONECT 2302 2301 CONECT 2303 2301 CONECT 2304 2299 2305 CONECT 2305 2304 2306 2307 CONECT 2306 2305 CONECT 2307 2305 CONECT 2308 2299 2309 CONECT 2309 2308 2310 2311 CONECT 2310 2309 CONECT 2311 2309 CONECT 2312 2315 CONECT 2313 2314 2316 CONECT 2314 2313 2317 CONECT 2315 2312 2318 CONECT 2316 2313 2319 CONECT 2317 2314 2320 CONECT 2318 2315 2321 CONECT 2319 2316 2322 CONECT 2320 2317 2323 CONECT 2321 2318 2324 CONECT 2322 2319 2324 CONECT 2323 2320 2325 CONECT 2324 2321 2322 CONECT 2325 2323 2326 CONECT 2326 2325 2327 CONECT 2327 2326 CONECT 2328 2331 CONECT 2329 2330 2332 CONECT 2330 2329 2333 CONECT 2331 2328 2335 CONECT 2332 2329 2336 CONECT 2333 2330 2337 CONECT 2334 2348 2350 CONECT 2335 2331 2338 CONECT 2336 2332 2339 CONECT 2337 2333 2340 CONECT 2338 2335 2341 CONECT 2339 2336 2341 CONECT 2340 2337 2342 CONECT 2341 2338 2339 CONECT 2342 2340 2343 CONECT 2343 2342 2344 CONECT 2344 2343 2345 CONECT 2345 2344 2347 CONECT 2346 2348 2352 CONECT 2347 2345 2349 2352 CONECT 2348 2334 2346 2351 CONECT 2349 2347 CONECT 2350 2334 CONECT 2351 2348 CONECT 2352 2346 2347 CONECT 2353 2356 CONECT 2354 2355 2357 CONECT 2355 2354 2358 CONECT 2356 2353 2359 CONECT 2357 2354 2360 CONECT 2358 2355 2361 CONECT 2359 2356 2362 CONECT 2360 2357 2363 CONECT 2361 2358 2364 CONECT 2362 2359 2365 CONECT 2363 2360 2365 CONECT 2364 2361 CONECT 2365 2362 2363 CONECT 2366 2367 2368 CONECT 2367 2366 2369 CONECT 2368 2366 2371 CONECT 2369 2367 2372 CONECT 2370 2382 2384 CONECT 2371 2368 2373 CONECT 2372 2369 2374 CONECT 2373 2371 2375 CONECT 2374 2372 2376 CONECT 2375 2373 CONECT 2376 2374 2377 CONECT 2377 2376 2378 CONECT 2378 2377 2379 CONECT 2379 2378 2381 CONECT 2380 2382 2386 CONECT 2381 2379 2383 2386 CONECT 2382 2370 2380 2385 CONECT 2383 2381 CONECT 2384 2370 CONECT 2385 2382 CONECT 2386 2380 2381 CONECT 2387 2390 CONECT 2388 2389 2391 CONECT 2389 2388 2392 CONECT 2390 2387 2394 CONECT 2391 2388 2395 CONECT 2392 2389 2396 CONECT 2393 2407 2409 CONECT 2394 2390 2397 CONECT 2395 2391 2398 CONECT 2396 2392 2399 CONECT 2397 2394 2400 CONECT 2398 2395 2400 CONECT 2399 2396 2401 CONECT 2400 2397 2398 CONECT 2401 2399 2402 CONECT 2402 2401 2403 CONECT 2403 2402 2404 CONECT 2404 2403 2406 CONECT 2405 2407 2411 CONECT 2406 2404 2408 2411 CONECT 2407 2393 2405 2410 CONECT 2408 2406 CONECT 2409 2393 CONECT 2410 2407 CONECT 2411 2405 2406 CONECT 2414 2276 CONECT 2415 2276 CONECT 2420 2275 CONECT 2425 2275 CONECT 2426 2275 CONECT 2433 2276 MASTER 388 0 9 13 0 0 21 6 2433 1 154 25 END