PDB
6D35
Resolution
3.9 Å
Released
May 23, 2018
Receptor
smo.S
Class
F
Species
Xenopus laevis
Ligand
Cholesterol
Function
Agonist
Reference
10.1016/J.CELL.2018.04.029

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Ligand Amino Acid Generic Number Segment Interaction Type
Cholesterol D68 N-term polar (charge-assisted hydrogen bond)
Cholesterol L81 N-term hydrophobic
Cholesterol L81 N-term Van der Waals
Cholesterol W82 N-term hydrophobic
Cholesterol W82 N-term Van der Waals
Cholesterol L85 N-term hydrophobic
Cholesterol I129 N-term Van der Waals
Cholesterol V130 N-term Van der Waals
Cholesterol V130 N-term hydrophobic
Cholesterol E133 N-term Van der Waals
Cholesterol R134 N-term Van der Waals
Cholesterol P137 N-term hydrophobic

NGL is a WebGL based 3D viewer powered by MMTF.

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Snake plot — Download: PNG | SVG
ICL1 W K N S N ICL1ECL1 Q F M D G A R D E I V C R G D G T M R L G E P T S N E T ECL1ICL2 T H Q P ICL2ECL2 A Q V D G D S V S G I C F V G Y K ECL2ICL3 P G L L S E K A ICL3ECL3 T N K P I P E C Y I K N R P ECL3N-term M S S M V P W I C W I G G F G F L L F I C T S G G V Q I N E T F Y M D K C K K T T T C E P L K Y N I C L G S V L P Y A L T S T V L A E D S S S Q D E V H D K L S L W S G L R N A P R C W D A I R P L L C A V Y M P K C E G G K V E L P S Q G L C Q T T R V P C A I V A R E R G W P D F L K C T T D Y F P E G C P N E V Q N I K F N S S G Q C E A P L V R T D N P K S W Y E D V E G C G I Q C Q N P L F N-termC-term G R S D D E P K R I K K S K M I A K A F S K R K E L L N N P E K E L S F S L H S V S H E G P V A G L N F D M N E P S A D M S S A W A Q H V T K M V A R R G A I L P Q D V S V T P V A T P V P P E E R D Q W F I E G D I P Q G M V K K M S K K K K R R K K K E I Q P L E A K T V K E H F H S R A N T A V P R L P K L P L K T G L V T R S K P Q E V D E T L P G S Y R E F R R L P N I Q E K L Y P V E G V N N N L G Y T R Y P Q S N M I S H P F A A D K M P L T D E S R V A Y V P V P K H D G V F Q Y S S A N S Y S N P M D L T S Y R G R T Q P R W T E N P P M H S R A N L M D A E L M D T D S D F C-term T N K E H R E M H I Y I A I F S S V T I F C T F F T L A T F L A D R Y P A V I L F Y V N A C F F V G S I G W L A L S C V I I F I I V Y Y S M M S G V I W F V M L T Y A W H T S F K A L G T L S G K T S Y F H L I T W S I P F V L T V A I L A V N Y H Y R A G F V L A P I G L V L I G G G Y F L I R G V M T L F S I K S N H A S K I N E T M L R L G I F G F L A F G F V L I T F G C H F Y D F F N Q A E W E R S F R E Y V L C E A N V T I A E Q S L L V E K I N L F A M F G T G I S M S T W V W T K A W K R I L T I I I A W C R
Helix box plot — Download: PNG | SVG F T C F I T V S S F I A I Y I H M E R H 1 F Y V N A C F F V G S I G W L A 2 M V F W I V G S M M S Y Y V I I F I I V 3 T S Y F H L I T W S I P F V L T V A I L 4 L F Y G G G I L V L G I P A L V F G A R Y 5 G I F G F L A F G F V L I T F G C H F Y 6 T S M S I G T G F M A F L N I K E V L L 7

GPCRdb(A)
GPCRdb(F)
smo.S