Number of structures, including multiple of same receptor (complex)

Class
(Family)		 A (Rhodopsin) B1 (Secretin) B2 (Adhesion) C (Glutamate) D1
(Ste2-like fungal pheromone) 		F (Frizzled) T2 (Taste 2) Total
Receptors 904 125 31 74 1 22 3 1160
Receptor - ligand complexes 896 124 29 73 1 20 3 1146
Receptor - G protein complexes 433 103 31 7 1 6 3 584
Active-state receptors* 520 108 31 23 1 7 3 693


Number of unique receptor complexes

Class
(Family)		 A (Rhodopsin) B1 (Secretin) B2 (Adhesion) C (Glutamate) D1
(Ste2-like fungal pheromone) 		F (Frizzled) T2 (Taste 2) Total
Receptors** 147 15 9 10 1 4 1 187
Receptor - ligand complexes 602 80 13 47 1 14 2 759
Receptor - G protein complexes 126 15 9 3 1 2 1 157
Active-state receptors* 130 15 9 6 1 2 1 164
*Active state is defined as agonist-bound and opened intracellular TM bundle. **Receptor-orthologues are only counted once.

Specific sets of structures can be downloaded from the Structures page.
The latest released structure is from 2023-08-16.



By class By ligand type The number of unique receptors with structures available. The number of unique receptors GPCR-ligand complexes. The number of structures available. The number of unique receptors with structures. The number of unique GPCR-ligand complexes. The number of structures available.


Structural coverage of GPCR Classes


Receptor names:

Class A
(Rhodopsin)


Structure state frequency (from low to high)
Structure state
○ Active ○ Intermediate ○ Inactive




Class A
Orphans

Class B1
(Secretin)

Class B2
(Adhesion)




Class C
(Glutamate)

Class F
(Frizzled)

Class T
(Taste 2)