ArrestinDb contains reference data, interactive visualization and experiment design tools for arrestins. ArrestinDb curates sequence alignments, structures and mutations from literature. Interactive diagrams visualise arrestin residues (e.g. snakeplot) and interactions with receptors.

ArrestinDb is developed by the David Gloriam group, integrates data from the research community and maintains an active collaboration with the Guide To Pharmacology (IUPHAR), GPCRmd, ERNEST and DrGPCR. If you use the ArrestinDb, please remember to cite us.

ArrestinDb statistics

  • 424 Human proteins
  • 43,132 Species orthologs
  • 69,605 Genetic variants
  • 1,789 Drugs
  • 209,520 Ligands
  • 432,715 Ligand bioactivities
  • 35,189 Ligand site mutations
  • 24,919 Ligand interactions
  • Experimental structures
  • 757 GPCRs
  • 399 G proteins
  • Structure models
  • 967 GPCRs
  • 3,091 GPCR-G protein complexes
  • 672 Refined GPCR structures
GPCRdb, GproteinDb, and ArrestinDb had 53,287 different users since this date last year and 5,486 users in the last 30 days (Google Analytics).

Latest release

April 30, 2022
  • Updated GPCR and G protein structures.
  • Updated GPCR ligand and bioactivity data to ChEMBL v30.
  • Updated GPCR homology and refined structure models.
  • Minor bug and performance fixes.