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ARRESTIN
| STRUCTURE
| RECEPTOR
| OTHER PROTEINS
| STRUCTURE LIGAND
| PHYSIOLOGICAL LIGAND
| REFERENCE
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Fam. | Arrestin | Species | Note | % of Seq | Method | PDB
| Resolution | UniProt
| IUPHAR | Receptor family | Class | Species | Receptor fusion | Antibodies | Other | Name | Type | Function | Name | Type | Authors | Reference | PDB Date | |||
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| Beta | Beta-arrestin-1 | Human | - | 86 | Cryo-EM | 8WU1 | - | 3.2 | CNR1 | CB1 | Cannabinoid | A (Rhodopsin) | Human | - |
Fab heavy chain Fab light chain |
- |
MDMB-Fubinaca
pubchem
gtoplig
|
small-molecule | Agonist | 2-arachidonoylglycerol, anandamide | small-molecule | Liao YY, Zhang H, Shen Q, Cai C, Ding Y, Shen DD, Guo J, Qin J, Dong Y, Zhang Y, Li XM | 10.1016/J.CELL.2023.11.017 | 2024-03-20 | 56847 | |
| Beta | Beta-arrestin-1 | Human | - | 84 | Cryo-EM | 8WRZ | - | 3.6 | CNR1 | CB1 | Cannabinoid | A (Rhodopsin) | Human | BRIL | scFv30 | - |
AM841
pubchem
gtoplig
chembl_ligand
|
small-molecule | Agonist | 2-arachidonoylglycerol, anandamide | small-molecule | Wang Y, Wu L, Wang T, Liu J, Li F, Jiang L, Fan Z, Yu Y, Chen N, Sun Q, Tan Q, Hua T, Liu ZJ | 10.1093/PROCEL/PWAD055 | 2024-02-28 | 56847 | |
| Beta | Beta-arrestin-1 | Bovine | - | - | Cryo-EM | 8J97 | - | 3.2 | - | - | - | - | - | - |
Fab30 Heavy Chain Fab30 Light Chain |
Muscarinic acetylcholine receptor M2 | - | - | - | - | - | Maharana J, Sano FK, Sarma P, Yadav MK, Duan L, Stepniewski TM, Chaturvedi M, Ranjan A, Singh V, Saha S, Mahajan G, Chami M, Shihoya W, Selent J, Chung KY, Banerjee R, Nureki O, Shukla AK | 38175886 | 2023-12-27 | 56851 | |
| Beta | Beta-arrestin-1 | Bovine | - | - | Cryo-EM | 8JAF | - | 3.1 | - | - | - | - | - | - |
Fab30 heavy chain Fab30 light chain |
Muscarinic acetylcholine receptor M2 | - | - | - | - | - | Maharana J, Sano FK, Sarma P, Yadav MK, Duan L, Stepniewski TM, Chaturvedi M, Ranjan A, Singh V, Saha S, Mahajan G, Chami M, Shihoya W, Selent J, Chung KY, Banerjee R, Nureki O, Shukla AK | 38175886 | 2023-12-27 | 56851 | |
| Beta | Beta-arrestin-1 | Rat | - | - | Cryo-EM | 8J8Z | - | 3.4 | - | - | - | - | - | - |
Fab30 Heavy Chain Fab30 Light Chain |
Atypical chemokine receptor 2 | - | - | - | - | - | Maharana J, Sano FK, Sarma P, Yadav MK, Duan L, Stepniewski TM, Chaturvedi M, Ranjan A, Singh V, Saha S, Mahajan G, Chami M, Shihoya W, Selent J, Chung KY, Banerjee R, Nureki O, Shukla AK | 38175886 | 2023-12-27 | 56850 | |
| Beta | Beta-arrestin-1 | Rat | - | - | Cryo-EM | 8JA3 | - | 3.9 | - | - | - | - | - | - |
Fab30 heavy chain Fab30 light chain |
C3a anaphylatoxin chemotactic receptor | - | - | - | - | - | Maharana J, Sano FK, Sarma P, Yadav MK, Duan L, Stepniewski TM, Chaturvedi M, Ranjan A, Singh V, Saha S, Mahajan G, Chami M, Shihoya W, Selent J, Chung KY, Banerjee R, Nureki O, Shukla AK | 38175886 | 2023-12-27 | 56850 | |
| Beta | Beta-arrestin-2 | Bovine | - | - | Cryo-EM | 8GO9 | - | 3.4 | - | - | - | - | - | - |
Fab30 Heavy Chain Fab30 Light Chain |
Atypical chemokine receptor 2 | - | - | - | - | - | Maharana J, Sano FK, Sarma P, Yadav MK, Duan L, Stepniewski TM, Chaturvedi M, Ranjan A, Singh V, Saha S, Mahajan G, Chami M, Shihoya W, Selent J, Chung KY, Banerjee R, Nureki O, Shukla AK | 38175886 | 2023-12-27 | 56888 | |
| Beta | Beta-arrestin-2 | Bovine | - | - | Cryo-EM | 8J8R | - | 2.9 | - | - | - | - | - | - |
Fab30 Heavy Chain Fab30 Light Chain |
Muscarinic acetylcholine receptor M2 | - | - | - | - | - | Maharana J, Sano FK, Sarma P, Yadav MK, Duan L, Stepniewski TM, Chaturvedi M, Ranjan A, Singh V, Saha S, Mahajan G, Chami M, Shihoya W, Selent J, Chung KY, Banerjee R, Nureki O, Shukla AK | 38175886 | 2023-12-27 | 56888 | |
| Beta | Beta-arrestin-2 | Bovine | - | - | Cryo-EM | 8J8V | - | 3.2 | - | - | - | - | - | - |
Fab30 Heavy Chain Fab30 Light Chain |
Atypical chemokine receptor 2 | - | - | - | - | - | Maharana J, Sano FK, Sarma P, Yadav MK, Duan L, Stepniewski TM, Chaturvedi M, Ranjan A, Singh V, Saha S, Mahajan G, Chami M, Shihoya W, Selent J, Chung KY, Banerjee R, Nureki O, Shukla AK | 38175886 | 2023-12-27 | 56888 | |
| Beta | Beta-arrestin-2 | Rat | - | - | Cryo-EM | 8J9K | - | 3.5 | - | - | - | - | - | - |
Fab6 light chain Fab6 heavy chain |
- | - | - | - | - | - | Maharana J, Sano FK, Sarma P, Yadav MK, Duan L, Stepniewski TM, Chaturvedi M, Ranjan A, Singh V, Saha S, Mahajan G, Chami M, Shihoya W, Selent J, Chung KY, Banerjee R, Nureki O, Shukla AK | 38175886 | 2023-12-27 | 56887 | |
| Beta | Beta-arrestin-1 | Bovine | - | 83 | Cryo-EM | 8JRU | - | 3.5 | GLR | glucagon | Glucagon | B1 (Secretin) | Human | - |
scFv30 Nanobody-32 |
- |
Apo (no ligand)
|
none | Apo (no ligand) | glucagon | peptide | Chen K, Zhang C, Lin S, Yan X, Cai H, Yi C, Ma L, Chu X, Liu Y, Zhu Y, Han S, Zhao Q, Wu B | 10.1038/S41586-023-06420-X | 2023-08-16 | 56851 | |
| Beta | Beta-arrestin-1 | Human | - | 85 | Cryo-EM | 8JRV | - | 3.3 | GLR | glucagon | Glucagon | B1 (Secretin) | Human | - |
scFv30 Nanobody-32 |
- |
glucagon
pubchem
gtoplig
chembl_ligand
drugbank
drug_central
gtoplig
pubchem
pubchem
pubchem
pubchem
pubchem
|
peptide | Agonist | glucagon | peptide | Chen K, Zhang C, Lin S, Yan X, Cai H, Yi C, Ma L, Chu X, Liu Y, Zhu Y, Han S, Zhao Q, Wu B | 10.1038/S41586-023-06420-X | 2023-08-16 | 56847 | |
| Beta | Beta-arrestin-1 | Rat | - | - | X-ray | 8HST | - | 2.7 | - | - | - | - | - | - | - | - | - | - | - | - | - | Yun Y, Yoon HJ, Jeong Y, Choi Y, Jang S, Chung KY, Lee HH | 37399373 | 2023-07-19 | 56850 | |
| Beta | Beta-arrestin-1 | Rat | - | - | X-ray | 8HSV | - | 3.0 | - | - | - | - | - | - | - | peptide from E3 ubiquitin-protein ligase Mdm2 | - | - | - | - | - | Yun Y, Yoon HJ, Jeong Y, Choi Y, Jang S, Chung KY, Lee HH | 37399373 | 2023-07-19 | 56850 | |
| Beta | Beta-arrestin-1 | Human | - | - | X-ray | 8AS2 | - | 3.2 | - | - | - | - | - | - |
Fab30 heavy chain Fab30 light chain |
C-C chemokine receptor type 5 | - | - | - | - | - | Isaikina P, Petrovic I, Jakob RP, Sarma P, Ranjan A, Baruah M, Panwalkar V, Maier T, Shukla AK, Grzesiek S | 37244255 | 2023-06-07 | 56847 | |
| Beta | Beta-arrestin-1 | Human | - | - | X-ray | 8AS3 | - | 3.5 | - | - | - | - | - | - |
Fab30 heavy chain Fab30 light chain |
C-C chemokine receptor type 5 | - | - | - | - | - | Isaikina P, Petrovic I, Jakob RP, Sarma P, Ranjan A, Baruah M, Panwalkar V, Maier T, Shukla AK, Grzesiek S | 37244255 | 2023-06-07 | 56847 | |
| Beta | Beta-arrestin-1 | Human | - | - | X-ray | 8AS4 | - | 2.3 | - | - | - | - | - | - | - | - | - | - | - | - | - | Isaikina P, Petrovic I, Jakob RP, Sarma P, Ranjan A, Baruah M, Panwalkar V, Maier T, Shukla AK, Grzesiek S | 37244255 | 2023-06-07 | 56847 | |
| Beta | Beta-arrestin-1 | Rat | - | - | Cryo-EM | 8GO8 | - | 3.4 | - | - | - | - | - | - |
Fab30 heavy chain Fab30 light chain |
C5a anaphylatoxin chemotactic receptor 1 | - | - | - | - | - | Maharana J, Sarma P, Yadav MK, Saha S, Singh V, Saha S, Chami M, Banerjee R, Shukla AK | 37209686 | 2023-05-17 | 56850 | |
| Beta | Beta-arrestin-1 | Rat | - | - | Cryo-EM | 8GP3 | - | 4.8 | - | - | - | - | - | - |
Fab30 Heavy Chain Fab30 Light Chain |
C-X-C chemokine receptor type 4 | - | - | - | - | - | Maharana J, Sarma P, Yadav MK, Saha S, Singh V, Saha S, Chami M, Banerjee R, Shukla AK | 37209686 | 2023-05-17 | 56850 | |
| Beta | Beta-arrestin-1 | Rat | - | - | Cryo-EM | 8I0Q | - | 4.5 | - | - | - | - | - | - |
Fab30 Heavy Chain Fab30 Light Chain |
C-X-C chemokine receptor type 4 | - | - | - | - | - | Maharana J, Sarma P, Yadav MK, Saha S, Singh V, Saha S, Chami M, Banerjee R, Shukla AK | 37209686 | 2023-05-17 | 56850 | |
| Beta | Beta-arrestin-2 | Bovine | - | - | Cryo-EM | 8GOC | - | 4.2 | - | - | - | - | - | - |
Fab30 Heavy Chain Fab30 Light Chain |
Vasopressin V2 receptor | - | - | - | - | - | Maharana J, Sarma P, Yadav MK, Saha S, Singh V, Saha S, Chami M, Banerjee R, Shukla AK | 37209686 | 2023-05-17 | 56888 | |
| Beta | Beta-arrestin-2 | Bovine | - | - | Cryo-EM | 8GOO | - | 4.4 | - | - | - | - | - | - |
Fab30 Heavy Chain Fab30 Light Chain |
C5a anaphylatoxin chemotactic receptor 1 | - | - | - | - | - | Maharana J, Sarma P, Yadav MK, Saha S, Singh V, Saha S, Chami M, Banerjee R, Shukla AK | 37209686 | 2023-05-17 | 56888 | |
| Beta | Beta-arrestin-2 | Bovine | - | - | Cryo-EM | 8I0Z | - | 4.3 | - | - | - | - | - | - |
Fab30 Heavy Chain Fab30 Light Chain |
C5a anaphylatoxin chemotactic receptor 1 | - | - | - | - | - | Maharana J, Sarma P, Yadav MK, Saha S, Singh V, Saha S, Chami M, Banerjee R, Shukla AK | 37209686 | 2023-05-17 | 56888 | |
| Beta | Beta-arrestin-2 | Bovine | - | - | Cryo-EM | 8I10 | - | 4.0 | - | - | - | - | - | - |
Fab30 Heavy Chain Fab30 Light Chain |
Vasopressin V2 receptor | - | - | - | - | - | Maharana J, Sarma P, Yadav MK, Saha S, Singh V, Saha S, Chami M, Banerjee R, Shukla AK | 37209686 | 2023-05-17 | 56888 | |
| Beta | Beta-arrestin-1 | Human | - | 85 | Cryo-EM | 7SRS | - | 3.3 | 5HT2B | 5-HT2B | 5-Hydroxytryptamine | A (Rhodopsin) | Human | - |
Fab light chain Fab heavy chain Fab30 heavy chain Fab30 light chain |
- |
Lysergide
pubchem
gtoplig
chembl_ligand
drugbank
drug_central
|
small-molecule | Agonist | 5-hydroxytryptamine | small-molecule | Cao C, Barros-Alvarez X, Zhang S, Kim K, Damgen MA, Panova O, Suomivuori CM, Fay JF, Zhong X, Krumm BE, Gumpper RH, Seven AB, Robertson MJ, Krogan NJ, Huttenhain R, Nichols DE, Dror RO, Skiniotis G, Roth BL | 10.1016/J.NEURON.2022.08.006 | 2022-09-21 | 56847 | |
| Beta | Beta-arrestin-1 | Human | - | 84 | Cryo-EM | 7R0C | - | 4.7 | V2R | V2 | Vasopressin and oxytocin | A (Rhodopsin) | Human | - | scFv30 | - |
vasopressin
pubchem
gtoplig
chembl_ligand
drugbank
drug_central
pubchem
|
peptide | Agonist | oxytocin, vasopressin | peptide | Bous J, Fouillen A, Orcel H, Trapani S, Cong X, Fontanel S, Saint-Paul J, Lai-Kee-Him J, Urbach S, Sibille N, Sounier R, Granier S, Mouillac B, Bron P | 10.1126/SCIADV.ABO7761 | 2022-09-14 | 56847 | |
| Beta | Beta-arrestin-1 | Human | - | - | Cryo-EM | 7R0J | - | 4.2 | - | - | - | - | - | - | ScFv30 | V2R Cter | - | - | - | - | - | Bous J, Fouillen A, Orcel H, Trapani S, Cong X, Fontanel S, Saint-Paul J, Lai-Kee-Him J, Urbach S, Sibille N, Sounier R, Granier S, Mouillac B, Bron P | 36054364 | 2022-09-14 | 56847 | |
| Visual | S-arrestin | Bovine | - | - | X-ray | 7F1W | - | 3.1 | - | - | - | - | - | - | - | - | - | - | - | - | - | Sander CL, Luu J, Kim K, Furkert D, Jang K, Reichenwallner J, Kang M, Lee HJ, Eger BT, Choe HW, Fiedler D, Ernst OP, Kim YJ, Palczewski K, Kiser PD | 34678158 | 2021-10-27 | 56930 | |
| Visual | S-arrestin | Bovine | - | - | X-ray | 7F1X | - | 3.0 | - | - | - | - | - | - | - | - | - | - | - | - | - | Sander CL, Luu J, Kim K, Furkert D, Jang K, Reichenwallner J, Kang M, Lee HJ, Eger BT, Choe HW, Fiedler D, Ernst OP, Kim YJ, Palczewski K, Kiser PD | 34678158 | 2021-10-27 | 56930 | |
| Visual | S-arrestin | Bovine | - | - | X-ray | 7JSM | - | 2.5 | - | - | - | - | - | - | - | - | - | - | - | - | - | Sander CL, Luu J, Kim K, Furkert D, Jang K, Reichenwallner J, Kang M, Lee HJ, Eger BT, Choe HW, Fiedler D, Ernst OP, Kim YJ, Palczewski K, Kiser PD | 34678158 | 2021-10-13 | 56930 | |
| Visual | S-arrestin | Bovine | - | - | X-ray | 7JTB | - | 2.6 | - | - | - | - | - | - | - | - | - | - | - | - | - | Sander CL, Luu J, Kim K, Furkert D, Jang K, Reichenwallner J, Kang M, Lee HJ, Eger BT, Choe HW, Fiedler D, Ernst OP, Kim YJ, Palczewski K, Kiser PD | 34678158 | 2021-10-13 | 56930 | |
| Visual | S-arrestin | Bovine | - | - | X-ray | 7JXA | - | 2.4 | - | - | - | - | - | - | - | - | - | - | - | - | - | Sander CL, Luu J, Kim K, Furkert D, Jang K, Reichenwallner J, Kang M, Lee HJ, Eger BT, Choe HW, Fiedler D, Ernst OP, Kim YJ, Palczewski K, Kiser PD | 34678158 | 2021-10-13 | 56930 | |
| Visual | S-arrestin | Bovine | - | - | X-ray | 7MOR | - | 2.8 | - | - | - | - | - | - | - | - | - | - | - | - | - | Sander CL, Luu J, Kim K, Furkert D, Jang K, Reichenwallner J, Kang M, Lee HJ, Eger BT, Choe HW, Fiedler D, Ernst OP, Kim YJ, Palczewski K, Kiser PD | 34678158 | 2021-10-13 | 56930 | |
| Visual | S-arrestin | Bovine | - | - | X-ray | 7MP0 | - | 2.6 | - | - | - | - | - | - | - | - | - | - | - | - | - | Sander CL, Luu J, Kim K, Furkert D, Jang K, Reichenwallner J, Kang M, Lee HJ, Eger BT, Choe HW, Fiedler D, Ernst OP, Kim YJ, Palczewski K, Kiser PD | 34678158 | 2021-10-13 | 56930 | |
| Visual | S-arrestin | Bovine | - | - | X-ray | 7MP1 | - | 2.7 | - | - | - | - | - | - | - | - | - | - | - | - | - | Sander CL, Luu J, Kim K, Furkert D, Jang K, Reichenwallner J, Kang M, Lee HJ, Eger BT, Choe HW, Fiedler D, Ernst OP, Kim YJ, Palczewski K, Kiser PD | 34678158 | 2021-10-13 | 56930 | |
| Visual | S-arrestin | Bovine | - | - | X-ray | 7MP2 | - | 3.0 | - | - | - | - | - | - | - | - | - | - | - | - | - | Sander CL, Luu J, Kim K, Furkert D, Jang K, Reichenwallner J, Kang M, Lee HJ, Eger BT, Choe HW, Fiedler D, Ernst OP, Kim YJ, Palczewski K, Kiser PD | 34678158 | 2021-10-13 | 56930 | |
| Beta | Beta-arrestin-1 | Bovine | - | - | X-ray | 7DF9 | - | 3.2 | - | - | - | - | - | - |
Fab30 Light Chain Fab30 Heavy Chain |
Vasopressin V2 receptor phosphopeptide | - | - | - | - | - | He QT, Xiao P, Huang SM, Jia YL, Zhu ZL, Lin JY, Yang F, Tao XN, Zhao RJ, Gao FY, Niu XG, Xiao KH, Wang J, Jin C, Sun JP, Yu X | 33888704 | 2021-07-28 | 56851 | |
| Beta | Beta-arrestin-1 | Bovine | - | - | X-ray | 7DFA | - | 2.5 | - | - | - | - | - | - |
Fab30 Heavy Chain Fab30 Light Chain |
VaRpp-4 | - | - | - | - | - | He QT, Xiao P, Huang SM, Jia YL, Zhu ZL, Lin JY, Yang F, Tao XN, Zhao RJ, Gao FY, Niu XG, Xiao KH, Wang J, Jin C, Sun JP, Yu X | 33888704 | 2021-07-28 | 56851 | |
| Beta | Beta-arrestin-1 | Bovine | - | - | X-ray | 7DFB | - | 3.3 | - | - | - | - | - | - |
Fab30 Light Chain Fab30 Heavy Chain |
V2Rpp-6-7 | - | - | - | - | - | He QT, Xiao P, Huang SM, Jia YL, Zhu ZL, Lin JY, Yang F, Tao XN, Zhao RJ, Gao FY, Niu XG, Xiao KH, Wang J, Jin C, Sun JP, Yu X | 33888704 | 2021-07-28 | 56851 | |
| Beta | Beta-arrestin-1 | Bovine | - | - | X-ray | 7DFC | - | 2.5 | - | - | - | - | - | - |
Fab30 Light Chain Fab30 Heavy Chain |
V2Rpp-3 | - | - | - | - | - | He QT, Xiao P, Huang SM, Jia YL, Zhu ZL, Lin JY, Yang F, Tao XN, Zhao RJ, Gao FY, Niu XG, Xiao KH, Wang J, Jin C, Sun JP, Yu X | 33888704 | 2021-07-28 | 56851 | |
| Beta | Beta-arrestin-1 | Human | - | 82 | Cryo-EM | 6TKO | 6TKO_refined | 3.3 | ADRB1 | β1 | Adrenoceptors | A (Rhodopsin) | Wild turkey | - |
Fab30 heavy chain Fab30 light chain |
- |
ARFORMOTEROL
chembl_ligand
chembl_ligand
chembl_ligand
chembl_ligand
pubchem
drugbank
drugbank
pubchem
|
small-molecule | Agonist | - | - | Lee Y, Warne T, Nehme R, Pandey S, Dwivedi-Agnihotri H, Chaturvedi M, Edwards PC, Garcia-Nafria J, Leslie AGW, Shukla AK, Tate CG | 10.1038/S41586-020-2419-1 | 2020-06-17 | 56847 | |
| Beta | Beta-arrestin-2 | Rat | - | - | X-ray | 6K3F | - | 2.3 | - | - | - | - | - | - | - | Peptide from Atypical chemokine receptor 3 | - | - | - | - | - | Min K, Yoon HJ, Park JY, Baidya M, Dwivedi-Agnihotri H, Maharana J, Chaturvedi M, Chung KY, Shukla AK, Lee HH | 32579945 | 2020-06-10 | 56887 | |
| Beta | Beta-arrestin-1 | Rat | - | 86 | Cryo-EM | 6U1N | 6U1N_refined | 4.0 | ACM2 | M2 | Acetylcholine (muscarinic) | A (Rhodopsin) | Human | - |
Fab30 light chain Fab30 heavy chain |
- |
LY2119620
pubchem
gtoplig
chembl_ligand
|
small-molecule | Agonist | acetylcholine | small-molecule | Staus DP, Hu H, Robertson MJ, Kleinhenz ALW, Wingler LM, Capel WD, Latorraca NR, Lefkowitz RJ, Skiniotis G | 10.1038/S41586-020-1954-0 | 2020-02-26 | 56850 | |
| Beta | Beta-arrestin-1 | Human | - | 83 | Cryo-EM | 6UP7 | 6UP7_refined | 4.2 | NTR1 | NTS1 | Neurotensin | A (Rhodopsin) | Human | - | - | - |
JMV431
gtoplig
chembl_ligand
pubchem
|
peptide | Agonist | large neuromedin N, neuromedin N, neurotensin, large neurotensin | peptide | Huang W, Masureel M, Qu Q, Janetzko J, Inoue A, Kato HE, Robertson MJ, Nguyen KC, Glenn JS, Skiniotis G, Kobilka BK | 10.1038/S41586-020-1953-1 | 2020-02-26 | 56847 | |
| Beta | Beta-arrestin-1 | Rat | - | - | X-ray | 6KL7 | - | 2.8 | - | - | - | - | - | - | - | - | - | - | - | - | - | Kang H, Yang HS, Ki AY, Ko SB, Kim KW, Shim CY, Kim K, Choi HJ, Chung KY | 31948726 | 2020-01-29 | 56850 | |
| Beta | Beta-arrestin-1 | Human | - | 84 | Cryo-EM | 6PWC | 6PWC_refined | 4.9 | NTR1 | NTS1 | Neurotensin | A (Rhodopsin) | Human | - |
Fab30 heavy chain Fab30 light chain |
- |
CHEMBL48981
chembl_ligand
pubchem
|
protein | Agonist | large neuromedin N, neuromedin N, neurotensin, large neurotensin | peptide | Yin W, Li Z, Jin M, Yin YL, de Waal PW, Pal K, Yin Y, Gao X, He Y, Gao J, Wang X, Zhang Y, Zhou H, Melcher K, Jiang Y, Cong Y, Edward Zhou X, Yu X, Eric Xu H | 10.1038/S41422-019-0256-2 | 2019-12-04 | 56847 | |
| Beta | Beta-arrestin-1 | Bovine | - | - | Cryo-EM | 6NI2 | - | 4.0 | - | - | - | - | - | - |
Nanobody 32 Fab30 Heavy Chain Fab30 Light Chain |
Vasopressin V2 receptor | - | - | - | - | - | Nguyen AH, Thomsen ARB, Cahill TJ 3rd, Huang R, Huang LY, Marcink T, Clarke OB, Heissel S, Masoudi A, Ben-Hail D, Samaan F, Dandey VP, Tan YZ, Hong C, Mahoney JP, Triest S, Little J 4th, Chen X, Sunahara R, Steyaert J, Molina H, Yu Z, des Georges A, Lefkowitz RJ | 31740855 | 2019-11-20 | 56851 | |
| Visual | Visual arrestin | Longfin inshore squid | - | - | X-ray | 6BK9 | - | 3.0 | - | - | - | - | - | - | - | - | - | - | - | - | - | Bandyopadhyay A, Van Eps N, Eger BT, Rauscher S, Yedidi RS, Moroni T, West GM, Robinson KA, Griffin PR, Mitchell J, Ernst OP | 30120952 | 2018-09-19 | 56936 | |
| Beta | Beta-arrestin-2 | Bovine | - | - | X-ray | 5TV1 | - | 2.4 | - | - | - | - | - | - | - | - | - | - | - | - | - | Chen Q, Perry NA, Vishnivetskiy SA, Berndt S, Gilbert NC, Zhuo Y, Singh PK, Tholen J, Ohi MD, Gurevich EV, Brautigam CA, Klug CS, Gurevich VV, Iverson TM | 29127291 | 2017-11-22 | 56888 | |
| Visual | S-arrestin | Mouse | - | 90 | X-ray | 5W0P | 5W0P_refined | 3.0 | OPSD | Rhodopsin | Opsins | A (Rhodopsin) | Human | T4-Lysozyme | - | - |
Apo (no ligand)
|
none | Apo (no ligand) | - | - | Zhou XE, He Y, de Waal PW, Gao X, Kang Y, Van Eps N, Yin Y, Pal K, Goswami D, White TA, Barty A, Latorraca NR, Chapman HN, Hubbell WL, Dror RO, Stevens RC, Cherezov V, Gurevich VV, Griffin PR, Ernst OP, Melcher K, Xu HE | 10.1016/J.CELL.2017.07.002 | 2017-08-09 | 56919 | |
| Visual | S-arrestin | Mouse | - | 86 | X-ray | 5DGY | 5DGY_refined | 7.7 | OPSD | Rhodopsin | Opsins | A (Rhodopsin) | Human | T4-Lysozyme | - | - |
Apo (no ligand)
|
none | Apo (no ligand) | - | - | Zhou XE, Gao X, Barty A, Kang Y, He Y, Liu W, Ishchenko A, White TA, Yefanov O, Han GW, Xu Q, de Waal PW, Suino-Powell KM, Boutet S, Williams GJ, Wang M, Li D, Caffrey M, Chapman HN, Spence JC, Fromme P, Weierstall U, Stevens RC, Cherezov V, Melcher K, Xu HE | 10.1038/SDATA.2016.21 | 2016-03-23 | 56919 | |
| Visual | S-arrestin | Bovine | - | - | X-ray | 4ZRG | - | 2.7 | - | - | - | - | - | - | - | - | - | - | - | - | - | Granzin J, Stadler A, Cousin A, Schlesinger R, Batra-Safferling R | 26510463 | 2015-11-11 | 56930 | |
| Visual | S-arrestin | Mouse | - | 86 | X-ray | 4ZWJ | 4ZWJ_refined | 3.3 | OPSD | Rhodopsin | Opsins | A (Rhodopsin) | Human | T4-Lysozyme | - | - |
Apo (no ligand)
|
none | Apo (no ligand) | - | - | Kang Y, Zhou XE, Gao X, He Y, Liu W, Ishchenko A, Barty A, White TA, Yefanov O, Han GW, Xu Q, de Waal PW, Ke J, Tan MH, Zhang C, Moeller A, West GM, Pascal BD, Van Eps N, Caro LN, Vishnivetskiy SA, Lee RJ, Suino-Powell KM, Gu X, Pal K, Ma J, Zhi X, Boutet S, Williams GJ, Messerschmidt M, Gati C, Zatsepin NA, Wang D, James D, Basu S, Roy-Chowdhury S, Conrad CE, Coe J, Liu H, Lisova S, Kupitz C, Grotjohann I, Fromme R, Jiang Y, Tan M, Yang H, Li J, Wang M, Zheng Z, Li D, Howe N, Zhao Y, Standfuss J, Diederichs K, Dong Y, Potter CS, Carragher B, Caffrey M, Jiang H, Chapman HN, Spence JC, Fromme P, Weierstall U, Ernst OP, Katritch V, Gurevich VV, Griffin PR, Hubbell WL, Stevens RC, Cherezov V, Melcher K, Xu HE | 10.1038/NATURE14656 | 2015-07-29 | 56919 | |
| Visual | S-arrestin | Mouse | Fragment | 2 | X-ray | 4PXF | 4PXF_refined | 2.8 | OPSD | Rhodopsin | Opsins | A (Rhodopsin) | Bovine | - | - | - |
B-Octylglucoside
pubchem
|
small-molecule | unknown | - | - | Szczepek M, Beyriere F, Hofmann KP, Elgeti M, Kazmin R, Rose A, Bartl FJ, von Stetten D, Heck M, Sommer ME, Hildebrand PW, Scheerer P | 10.1038/NCOMMS5801 | 2014-09-17 | 56919 | |
| Visual | S-arrestin | Bovine | - | - | X-ray | 4J2Q | - | 3.0 | - | - | - | - | - | - | - | - | - | - | - | - | - | Kim YJ, Hofmann KP, Ernst OP, Scheerer P, Choe HW, Sommer ME | 23604253 | 2013-05-01 | 56930 | |
| Beta | Beta-arrestin-1 | Rat | - | - | X-ray | 4JQI | - | 2.6 | - | - | - | - | - | - |
Fab30 heavy chain Fab30 light chain |
Vasopressin V2 receptor phosphopeptide | - | - | - | - | - | Shukla AK, Manglik A, Kruse AC, Xiao K, Reis RI, Tseng WC, Staus DP, Hilger D, Uysal S, Huang LY, Paduch M, Tripathi-Shukla P, Koide A, Koide S, Weis WI, Kossiakoff AA, Kobilka BK, Lefkowitz RJ | 23604254 | 2013-04-17 | 56850 | |
| Visual | S-arrestin | Bovine | - | - | X-ray | 3UGU | - | 1.9 | - | - | - | - | - | - | - | - | - | - | - | - | - | Granzin J, Cousin A, Weirauch M, Schlesinger R, Buldt G, Batra-Safferling R | 22306737 | 2012-02-08 | 56930 | |
| Visual | S-arrestin | Bovine | - | - | X-ray | 3UGX | - | 2.6 | - | - | - | - | - | - | - | - | - | - | - | - | - | Granzin J, Cousin A, Weirauch M, Schlesinger R, Buldt G, Batra-Safferling R | 22306737 | 2012-02-08 | 56930 | |
| Beta | Beta-arrestin-2 | Bovine | - | - | X-ray | 3P2D | - | 3.0 | - | - | - | - | - | - | - | - | - | - | - | - | - | Zhan X, Gimenez LE, Gurevich VV, Spiller BW | 21215759 | 2011-01-26 | 56888 | |
| Beta | Beta-arrestin-1 | Bovine | - | - | X-ray | 2WTR | - | 2.9 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 2009-09-29 | 56851 | |
| Beta | Beta-arrestin-1 | Bovine | - | - | X-ray | 3GC3 | - | 2.2 | - | - | - | - | - | - | - | Clathrin heavy chain 1 | - | - | - | - | - | Kang DS, Kern RC, Puthenveedu MA, von Zastrow M, Williams JC, Benovic JL | 19710023 | 2009-08-25 | 56851 | |
| Beta | Beta-arrestin-1 | Bovine | - | - | X-ray | 3GD1 | - | 3.5 | - | - | - | - | - | - | - |
Clathrin heavy chain 1 clathrin |
- | - | - | - | - | Kang DS, Kern RC, Puthenveedu MA, von Zastrow M, Williams JC, Benovic JL | 19710023 | 2009-08-25 | 56851 | |
| Beta | Beta-arrestin-1 | Human | - | - | X-ray | 2IV8 | - | 2.8 | - | - | - | - | - | - | - | AP-2 complex subunit Beta-1 | - | - | - | - | - | Schmid EM, Ford MG, Burtey A, Praefcke GJ, Peak-Chew SY, Mills IG, Benmerah A, McMahon HT | 16903783 | 2007-06-12 | 56847 | |
| Beta | Beta-arrestin-1 | Bovine | - | - | X-ray | 1ZSH | - | 2.9 | - | - | - | - | - | - | - | - | - | - | - | - | - | Milano SK, Kim YM, Stefano FP, Benovic JL, Brenner C | 16439357 | 2006-01-31 | 56851 | |
| Visual | Arrestin-C | Eastern tiger salamander | - | - | X-ray | 1SUJ | - | 2.4 | - | - | - | - | - | - | - | - | - | - | - | - | - | Sutton RB, Vishnivetskiy SA, Robert J, Hanson SM, Raman D, Knox BE, Kono M, Navarro J, Gurevich VV | 16289201 | 2005-08-23 | 56917 | |
| Beta | Beta-arrestin-1 | Bovine | - | - | X-ray | 1JSY | - | 2.9 | - | - | - | - | - | - | - | - | - | - | - | - | - | Milano SK, Pace HC, Kim YM, Brenner C, Benovic JL | 11876640 | 2002-03-27 | 56851 | |
| Beta | Beta-arrestin-1 | Bovine | - | - | X-ray | 1G4M | - | 1.9 | - | - | - | - | - | - | - | - | - | - | - | - | - | Han M, Gurevich VV, Vishnivetskiy SA, Sigler PB, Schubert C | 11566136 | 2001-10-03 | 56851 | |
| Beta | Beta-arrestin-1 | Bovine | - | - | X-ray | 1G4R | - | 2.2 | - | - | - | - | - | - | - | - | - | - | - | - | - | Han M, Gurevich VV, Vishnivetskiy SA, Sigler PB, Schubert C | 11566136 | 2001-10-03 | 56851 | |
| Visual | S-arrestin | Bovine | - | - | X-ray | 1CF1 | - | 2.8 | - | - | - | - | - | - | - | - | - | - | - | - | - | Hirsch JA, Schubert C, Gurevich VV, Sigler PB | 10219246 | 1999-04-16 | 56930 | |
| Visual | S-arrestin | Bovine | - | - | X-ray | 1AYR | - | 3.3 | - | - | - | - | - | - | - | - | - | - | - | - | - | Granzin J, Wilden U, Choe HW, Labahn J, Krafft B, Buldt G | 9495348 | 1998-11-25 | 56930 | |
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