PDB
6FKA
Resolution
2.7 Å
Released
April 4, 2018
Receptor
Rhodopsin
Class
A
Species
Bos taurus
Ligand
RS11
Function
Agonist
Reference
10.1073/PNAS.1718084115

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Ligand Amino Acid Generic Number Segment Interaction Type
RS11 L125 3.40x40 TM3 hydrophobic
RS11 Y191 ECL2 hydrophobic
RS11 M207 5.42x43 TM5 hydrophobic
RS11 F208 5.43x44 TM5 hydrophobic
RS11 F212 5.47x47 TM5 hydrophobic
RS11 W265 6.48x48 TM6 hydrophobic
RS11 Y268 6.51x51 TM6 hydrophobic
RS11 A272 6.55x55 TM6 hydrophobic

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Snake plot — Download: PNG | SVG
ICL1 K K L R ICL1ECL1 Y F V F ECL1ICL2 P M S N F R F ICL2ECL2 W S R Y I P E G M Q C S C G I D Y Y T P H E E T ECL2ICL3 Q E ICL3ECL3 Q G S D F ECL3N-term M N G T E G P N F Y V P F S N K T G V V R S P F E A P Q Y Y L A N-termC-term C G K N P L G D D E A S T T V S K T E T S Q V A P A C-term E P W Q F S M L A A Y M F L L I M L G F P I N F L T L Y V T V Q H T P L N Y I L L N L A V A D L F M V F G G F T T T L Y T S L H G G P T G C N L E G F F A T L G G E I A L W S L V V L A I E R Y V V V C K G E N H A I M G V A F T W V M A L A C A A P P L V G N N E S F V I Y M F V V H F I I P L I V I F F C Y G Q L V F T V K E A A A Q Q S A T T Q K A E K E V T R M V I I M V I A F L I C W L P Y A G V A F Y I F T H G P I F M T I P A F F A K T S A V Y N P V I Y I M M N K Q M V T F R N C T L C
Helix box plot — Download: PNG | SVG F N I P F G L M I L L F M Y A A L M S F 1 L N L A V A D L F M V G F G F T T T L Y T 2 V V L S W L A I E G G L T A F F G E L N 3 A I M G V A F T W V M A L A C A A P P L 4 Y C F F I V I L P I I F H V V F M Y I V F 5 I I M V I A F L I C W L P Y A G V A F Y 6 V P N Y V A S T K A F F A P I T M F I 7

GPCRdb(A)
GPCRdb(A)
Rhodopsin
TM3
3x40 3.40x40 L125
TM5
5x43 5.42x43 M207
5x44 5.43x44 F208
5x47 5.47x47 F212
TM6
6x48 6.48x48 W265
6x51 6.51x51 Y268
6x55 6.55x55 A272