Structure information

δ receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

6PT2

SPECIES

Homo sapiens

RESOLUTION

2.800

PREFERRED CHAIN

A

REFERENCE

10.1126/SCIADV.AAX9115

PUBLICATION DATE

Dec. 11, 2019

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
KGCHM07 W114 23.50x50 ECL1 hydrophobic
KGCHM07 Y129 3.33x33 TM3 hydrophobic
KGCHM07 M132 3.36x36 TM3 hydrophobic
KGCHM07 K214 5.39x40 TM5 Van der Waals
KGCHM07 K214 5.39x40 TM5 polar (hydrogen bond with backbone)
KGCHM07 V217 5.42x43 TM5 Van der Waals
KGCHM07 V217 5.42x43 TM5 hydrophobic
KGCHM07 W274 6.48x48 TM6 hydrophobic
KGCHM07 W274 6.48x48 TM6 Van der Waals
KGCHM07 I277 6.51x51 TM6 Van der Waals
KGCHM07 I277 6.51x51 TM6 hydrophobic
KGCHM07 H278 6.52x52 TM6 polar (hydrogen bond)
KGCHM07 F280 6.54x54 TM6 hydrophobic
KGCHM07 F280 6.54x54 TM6 Van der Waals
KGCHM07 V281 6.55x55 TM6 hydrophobic
KGCHM07 V281 6.55x55 TM6 Van der Waals
KGCHM07 W284 6.58x58 TM6 polar (hydrogen bond)
KGCHM07 I289 ECL3 Van der Waals
KGCHM07 R291 ECL3 Van der Waals
KGCHM07 L300 7.35x34 TM7 hydrophobic
KGCHM07 L300 7.35x34 TM7 Van der Waals
KGCHM07 I304 7.39x38 TM7 hydrophobic
KGCHM07 I304 7.39x38 TM7 Van der Waals
KGCHM07 Y308 7.43x42 TM7 Van der Waals

Ligands

KGCHM07

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Residue Diagrams

V N G L L G V A C V A S Y L A T I A I A 1 F N L A L A D A L A T S T L P F Q S A K 2 M T L T F I S T F M N Y Y D I S L V A K 3 A K L I N I C I W V L A S G V G V P I M 4 Y C V T I I L I P V V F A F L F V C I K T 5 L V V V G A F V V C W A P I H I F V I V 6 V P N L S S N A Y G L A I C L H L A A 7
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ICL1 T K M K ICL1ECL1 T W P F ECL1ICL2 P V K A L D F R ICL2ECL2 V T R P R D G A V V C M L Q F P S ECL2ICL3 R L L S G ICL3ECL3 D I D R R ECL3N-term M E P A P S A G A E L Q P P L F A N A S D A Y P S A C P S A G A N A S G P P N-termC-term P C G R P D P S S F S R A R E A T A R E R V T A C T P S D G P G G G A A A C-term G A R S A S S L A L A I A I T A L Y S A V C A V G L L G N V L V M F G I V R Y T A T N I Y I F N L A L A D A L A T S T L P F Q S A K Y L M E G E L L C K A V L S I D Y Y N M F T S I F T L T M M S V D R Y I A V C H T P A K A K L I N I C I W V L A S G V G V P I M V M A P S W Y W D T V T K I C V F L F A F V V P I L I I T V C Y G L M L L R L R S V S K E K D R S L R R I T R M V L V V V G A F V V C W A P I H I F V I V W T L V D P L V V A A L H L C I A L G Y A N S S L N P V L Y A F L D E N F R Q F K R C L C R K
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Residue Table


GPCRdb(A)
GPCRdb(A)
δ receptor
ECL1
23x50 23.50x50 W114
TM3
3x33 3.33x33 Y129
3x36 3.36x36 M132
TM5
5x40 5.39x40 K214
5x43 5.42x43 V217
TM6
6x48 6.48x48 W274
6x51 6.51x51 I277
6x52 6.52x52 H278
6x54 6.54x54 F280
6x55 6.55x55 V281
6x58 6.58x58 W284
TM7
7x34 7.35x34 L300
7x38 7.39x38 I304
7x42 7.43x42 Y308