Structure information

BLT1 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

7VKT

SPECIES

Homo sapiens

RESOLUTION

2.900

PREFERRED CHAIN

A

REFERENCE

10.1038/S41467-022-28820-9

PUBLICATION DATE

March 9, 2022

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
LTB<sub>4</sub> F74 2.60x60 TM2 hydrophobic
LTB<sub>4</sub> L78 2.64x64 TM2 hydrophobic
LTB<sub>4</sub> M101 3.36x36 TM3 hydrophobic
LTB<sub>4</sub> Y102 3.37x37 TM3 hydrophobic
LTB<sub>4</sub> W234 6.48x48 TM6 hydrophobic
LTB<sub>4</sub> N268 7.36x35 TM7 polar (hydrogen bond)
LTB<sub>4</sub> N268 7.36x35 TM7 Van der Waals
LTB<sub>4</sub> I271 7.39x38 TM7 hydrophobic
LTB<sub>4</sub> I271 7.39x38 TM7 Van der Waals
LTB<sub>4</sub> F275 7.43x42 TM7 Van der Waals
LTB<sub>4</sub> F275 7.43x42 TM7 hydrophobic

Ligands

LTB<sub>4</sub>

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Residue Diagrams

S N G P L G V A L A V S L L I I A L L S 1 L N L A L A D L A V L L T A P F F L H F 2 A T I L L V S A Y M S V G C V Y H C L R 3 A R R V L A G I W V L S F L L A T P V 4 Y S A V V A L F P L L F G T V A E F I L H 5 V L I I L T F A A F W L P Y H V V N L A 6 V P N V S S S L F A L A I L V N R A L 7
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ICL1 M Q K R ICL1ECL1 T W S F ECL1ICL2 P F V S Q K L R ICL2ECL2 T V V P W K T N M S L C F P R Y P ECL2ICL3 R F R R ICL3ECL3 Q A A G L ECL3N-term M N T T S S A A P P S L N-termC-term G V G F V A K L L E G T G S E A S S T R R G G S L G Q T A R S G P A A L E P G P S E S L T A S S P L K L N E L N C-term G V E F I S L L A I I L L S V A L A V G L P G N S F V V W S I L K R S V T A L M V L N L A L A D L A V L L T A P F F L H F L A Q G G L A G C R L C H Y V C G V S M Y A S V L L I T A M S L D R S L A V A R T K A M A R R V L A G I W V L S F L L A T P V L A Y R S E G H R A F H L I F E A V T G F L L P F L A V V A S Y S D I G R R L Q A R S R R T G R L V V L I I L T F A A F W L P Y H V V N L A E A G R A L A G G L V G K R L S L A R N V L I A L A F L S S S V N P V L Y A C A G G G L L R S A
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Residue Table


GPCRdb(A)
GPCRdb(A)
BLT1 receptor
TM2
2x60 2.60x60 F74
2x64 2.64x64 L78
TM3
3x36 3.36x36 M101
3x37 3.37x37 Y102
TM6
6x48 6.48x48 W234
TM7
7x35 7.36x35 N268
7x38 7.39x38 I271
7x42 7.43x42 F275