Structure information

μ receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

8EFQ

SPECIES

Homo sapiens

RESOLUTION

3.300

PREFERRED CHAIN

R

REFERENCE

10.1016/J.CELL.2022.09.041

PUBLICATION DATE

Nov. 9, 2022

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Ligand Interaction Browser

Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
DAMGO V145 3.28x28 TM3 hydrophobic
DAMGO D149 3.32x32 TM3 polar (charge-assisted hydrogen bond)
DAMGO M153 3.36x36 TM3 hydrophobic
DAMGO M153 3.36x36 TM3 Van der Waals
DAMGO C219 45.50x50 ECL2 Van der Waals
DAMGO V238 5.42x43 TM5 hydrophobic
DAMGO V238 5.42x43 TM5 Van der Waals
DAMGO I298 6.51x51 TM6 Van der Waals
DAMGO I298 6.51x51 TM6 hydrophobic
DAMGO H299 6.52x52 TM6 Van der Waals
DAMGO V302 6.55x55 TM6 Van der Waals
DAMGO V302 6.55x55 TM6 hydrophobic
DAMGO W320 7.35x34 TM7 Van der Waals
DAMGO I324 7.39x38 TM7 hydrophobic
DAMGO I324 7.39x38 TM7 Van der Waals
DAMGO Y328 7.43x42 TM7 Van der Waals

Ligands

DAMGO

3D interaction viewer Download PDB file

NGL is a WebGL based 3D viewer powered by MMTF.


Residue Diagrams

F N G F L G V V C V I S Y L A M I T I A 1 F N L A L A D A L A T S T L P F Q S V N 2 T C L T F I S T F M N Y Y D I S I V I K 3 A K I I N V C N W I L S S A I G L P V M 4 Y C V T I I L V P M I F A F I F V C I K L 5 L V V V A V F I V C W T P I H I Y V I I 6 V P N L C S N T Y G L A I C F H W S V 7
Download: PNG | SVG
ICL1 T K M K ICL1ECL1 T W P F ECL1ICL2 P V K A L D F R ICL2ECL2 T T K Y R Q G S I D C T L T F S H ECL2ICL3 R M L S G ICL3ECL3 T I P E ECL3N-term M D S S A A P T N A S N C T D A L A Y S S C S P A P S P G S W V N L S H L D G N L S D P C G P N R T D L G G R D S L C P P T G S P S N-termC-term P T S S N I E Q Q N S T R I R Q N T R D H P S T A N T V D R T N H Q L E N L E A E T A P L P C-term M I T A I T I M A L Y S I V C V V G L F G N F L V M Y V I V R Y T A T N I Y I F N L A L A D A L A T S T L P F Q S V N Y L M G G T I L C K I V I S I D Y Y N M F T S I F T L C T M S V D R Y I A V C H T P R N A K I I N V C N W I L S S A I G L P V M F M A P T W Y W E N L L K I C V F I F A F I M P V L I I T V C Y G L M I L R L K S V S K E K D R N L R R I T R M V L V V V A V F I V C W T P I H I Y V I I K A L V T T F Q T V S W H F C I A L G Y T N S C L N P V L Y A F L D E N F R E F K R C F C I
Download: PNG | SVG

Residue Table


GPCRdb(A)
GPCRdb(A)
μ receptor
TM3
3x28 3.28x28 V145
3x32 3.32x32 D149
3x36 3.36x36 M153
ECL2
45x50 45.50x50 C219
TM5
5x43 5.42x43 V238
TM6
6x51 6.51x51 I298
6x52 6.52x52 H299
6x55 6.55x55 V302
TM7
7x34 7.35x34 W320
7x38 7.39x38 I324
7x42 7.43x42 Y328