Structure information

CXCR3

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

8HNM

SPECIES

Homo sapiens

RESOLUTION

2.940

PREFERRED CHAIN

R

REFERENCE

10.1038/S41594-023-01175-5

PUBLICATION DATE

Nov. 29, 2023

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
CHEMBL2220409 Y60 1.39x39 TM1 hydrophobic
CHEMBL2220409 W109 2.60x60 TM2 hydrophobic
CHEMBL2220409 F131 3.32x32 TM3 hydrophobic
CHEMBL2220409 F135 3.36x36 TM3 aromatic (edge-to-face)
CHEMBL2220409 W268 6.48x48 TM6 hydrophobic
CHEMBL2220409 Y271 6.51x51 TM6 aromatic (face-to-edge)
CHEMBL2220409 Y308 7.43x42 TM7 hydrophobic

Ligands

CHEMBL2220409

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Residue Diagrams

G N G L L G L L F L L S Y L A P L F A R 1 L H L A V A D T L L V L T L P L W A V D 2 C A L L L A G A Y F N I N F L A G A V K 3 V T L T C L A V W G L C L L F A L P D 4 Y C Y A M V L L P L L F G A V L Q L V R L 5 V V V V V A F A L C W T P Y H L V V L V 6 L P N L C C H M Y G L G S T V S K A V 7
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ICL1 R T A L ICL1ECL1 Q W V F ECL1ICL2 A T Q L Y R R G P P ICL2ECL2 S A H H D E R L N A T H C Q Y N F ECL2ICL3 R G Q ICL3ECL3 A L A R ECL3N-term M V L E V S D H Q V L N D A E V A A L L E N F S S S Y D Y G E N E S D S C C T S P P C P N-termC-term G C P N Q R G L Q R Q P S S S R R D S S W S E T S E A S Y S G L C-term Q D F S L N F D R A F L P A L Y S L L F L L G L L G N G A V A A V L L S R S S T D T F L L H L A V A D T L L V L T L P L W A V D A A V G S G L C K V A G A L F N I N F Y A G A L L L A C I S F D R Y L N I V H A R V T L T C L A V W G L C L L F A L P D F I F L P Q V G R T A L R V L Q L V A G F L L P L L V M A Y C Y A H I L A V L L V S R R L R A M R L V V V V V V A F A L C W T P Y H L V V L V D I L M D L G N C G R E S R V D V A K S V T S G L G Y M H C C L N P L L Y A F V G V K M W M L F R E R L L L R
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Residue Table


GPCRdb(A)
GPCRdb(A)
CXCR3
TM1
1x39 1.39x39 Y60
TM2
2x60 2.60x60 W109
TM3
3x32 3.32x32 F131
3x36 3.36x36 F135
TM6
6x48 6.48x48 W268
6x51 6.51x51 Y271
TM7
7x42 7.43x42 Y308