Structure information

C5a1 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

8HQC

SPECIES

Mus musculus

RESOLUTION

3.890

PREFERRED CHAIN

A

REFERENCE

HTTPS://DOI.ORG/10.1016/J.CELL.2023.09.020

PUBLICATION DATE

Oct. 18, 2023

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
C5a I28 N-term hydrophobic
C5a H29 N-term polar (hydrogen bond)
C5a H29 N-term Van der Waals
C5a L92 2.60x60 TM2 Van der Waals
C5a L92 2.60x60 TM2 hydrophobic
C5a N100 ECL1 Van der Waals
C5a P113 3.29x29 TM3 Van der Waals
C5a R175 ECL2 Van der Waals
C5a E176 ECL2 polar (charge-assisted hydrogen bond)
C5a F181 ECL2 Van der Waals
C5a Y259 6.51x51 TM6 hydrophobic
C5a Y259 6.51x51 TM6 Van der Waals
C5a G263 6.55x55 TM6 Van der Waals
C5a I266 6.58x58 TM6 Van der Waals
C5a V287 7.39x38 TM7 Van der Waals
C5a V287 7.39x38 TM7 hydrophobic

Ligands

C5a

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Residue Diagrams

A N G P V G V L F V V S Y I I L A A V D 1 L N L A V A D L L S C L A L P V L F T T 2 T A L L L I S A Y M N L L I L S P L V I 3 A W M A C G V A W V L A L L L T I P S 4 Y C I N L T L L P L V F G V M L R L I A V 5 M A V V I C F F I F W L P Y Q V T G V M 6 I P N V C C N I Y A L S V C L S N L K 7
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ICL1 A R R ICL1ECL1 N Y W Y F ECL1ICL2 P I W C Q K V R ICL2ECL2 E A Y K D F Y S E H T V C G I N Y G G G ECL2ICL3 K A T R S ICL3ECL3 P P S ECL3N-term M D P I D N S S F E I N Y D H Y G T M D P N I P A D G I H L P K R N-termC-term L P S I I R N A L S E D S V G R D S K T F T P S T T D T S T R K S Q A V C-term Q P G D V A A L I I Y S V V F L V G V P G N A L V V W V T A F E A V N A I W F L N L A V A D L L S C L A L P V L F T T V L N H D A T A C I V L P S L I L L N M Y A S I L L L A T I S A D R F L L V F K G T G L A W M A C G V A W V L A L L L T I P S F V Y R S F P K E K A V A I L R L M V G F V L P L L T L N I C Y T F L L L R T W S R T K T L K V V M A V V I C F F I F W L P Y Q V T G V M I A W L S P T L K R V E K L N S L C V S L A Y I N C C V N P I I Y V M A G Q G F L R S H G R L
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Residue Table


GPCRdb(A)
GPCRdb(A)
C5a1 receptor
TM2
2x60 2.60x60 L92
TM3
3x29 3.29x29 P113
TM6
6x51 6.51x51 Y259
6x55 6.55x55 G263
6x58 6.58x58 I266
TM7
7x38 7.39x38 V287