PDB
9UWJ
Resolution
3.0 Å
Released
Feb. 4, 2026
Receptor
V1A
Class
A
Species
Homo sapiens
Ligand
balovaptan
Function
Antagonist
Reference
—

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file
Download list in excel
Ligand Amino Acid Generic Number Segment Interaction Type
balovaptan E54 1.35x35 TM1 polar (charge-assisted hydrogen bond)
balovaptan L58 1.39x39 TM1 hydrophobic
balovaptan L58 1.39x39 TM1 Van der Waals
balovaptan Q104 2.57x56 TM2 polar (hydrogen bond)
balovaptan Q104 2.57x56 TM2 polar (hydrogen bond)
balovaptan Q108 2.61x60 TM2 Van der Waals
balovaptan K128 3.29x29 TM3 polar (charge-assisted hydrogen bond)
balovaptan Q131 3.32x32 TM3 polar (hydrogen bond)
balovaptan V132 3.33x33 TM3 polar (hydrogen bond)
balovaptan M135 3.36x36 TM3 polar (hydrogen bond)
balovaptan Q185 4.60x61 TM4 polar (hydrogen bond)
balovaptan Q185 4.60x61 TM4 polar (hydrogen bond)
balovaptan F189 4.64x65 TM4 polar (hydrogen bond)
balovaptan F207 ECL2 Van der Waals
balovaptan Y216 5.38x39 TM5 hydrophobic
balovaptan Y216 5.38x39 TM5 Van der Waals
balovaptan V217 5.39x40 TM5 hydrophobic
balovaptan V217 5.39x40 TM5 Van der Waals
balovaptan M220 5.42x43 TM5 Van der Waals
balovaptan M220 5.42x43 TM5 hydrophobic
balovaptan F307 6.51x51 TM6 hydrophobic
balovaptan F307 6.51x51 TM6 Van der Waals
balovaptan F308 6.52x52 TM6 hydrophobic
balovaptan F308 6.52x52 TM6 Van der Waals
balovaptan Q311 6.55x55 TM6 Van der Waals
balovaptan A334 7.39x38 TM7 polar (hydrogen bond)
balovaptan L335 7.40x39 TM7 Van der Waals
balovaptan S338 7.43x42 TM7 polar (hydrogen bond)
balovaptan S338 7.43x42 TM7 polar (hydrogen bond)

NGL is a WebGL based 3D viewer powered by MMTF.

Download PDB file

Snake plot — Download: PNG | SVG
ICL1 P R K T ICL1ECL1 R F R G ECL1ICL2 P L K T L Q Q ICL2ECL2 S M I E V N N V T K A R D C W A T F I Q P ECL2ICL3 Q S K G A E Q A G V A F Q K G F L L A P C V S S V ICL3ECL3 P M S V W T E ECL3N-term M R L S A G P D A G P S G N S S P W W P L A T G A G N T S R E A E A L G E G N G P P R D V R N-termC-term M K E K F N K E D T D S M S R R Q T F Y S N N R S P T N S T G M W K D S P K S S K S I K F I P V S T C-term N E E L A K L E I A V L A V T F A V A V L G N S S V L L A L H R T S R M H L F I R H L S L A D L A V A F F Q V L P Q M C W D I T Y P D W L C R V V K H L Q V F G M F A S A Y M L V V M T A D R Y I A V C H P A R R S R L M I A A A W V L S F V L S T P Q Y F V F W G S R A Y V T W M T G G I F V A P V V I L G T C Y G F I C Y N I W C N V R G K T A S R K S I S R A K I R T V K M T F V I V T A Y I V C W A P F F I I Q M W S V W D S E N P T I T I T A L L G S L N S C C N P W I Y M F F S G H C V Q C Q N L L Q D S F P C
Helix box plot — Download: PNG | SVG S N G L V A V A F T V A L V A I E L K A 1 R H L S L A D L A V A F F Q V L P Q M C W 2 V V L M Y A S A F M G F V Q L H K V V R 3 S R L M I A A A W V L S F V L S T P Q 4 Y C T G L I V V P A V F I G G T M W T V Y 5 F V I V T A Y I V C W A P F F I I Q M W 6 W P N C C S N L S G L L A T I T I T P 7

GPCRdb(A)
GPCRdb(A)
V1A receptor
TM1
1x35 1.35x35 E54
1x39 1.39x39 L58
TM2
2x56 2.57x56 Q104
2x60 2.61x60 Q108
TM3
3x29 3.29x29 K128
3x32 3.32x32 Q131
3x33 3.33x33 V132
3x36 3.36x36 M135
TM4
4x61 4.60x61 Q185
4x65 4.64x65 F189
TM5
5x39 5.38x39 Y216
5x40 5.39x40 V217
5x43 5.42x43 M220
TM6
6x51 6.51x51 F307
6x52 6.52x52 F308
6x55 6.55x55 Q311
TM7
7x38 7.39x38 A334
7x39 7.40x39 L335
7x42 7.43x42 S338