oxytocin


SMILES None
InChIKey XNOPRXBHLZRZKH-DSZYJQQASA-N
Sequence CYIQNCPLG

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Peptide
Endogenous/Surrogate Endogenous
Approved drug Yes

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
V1A V1AR Human Vasopressin and oxytocin A pKi 6.9 7.6 8.3 Guide to Pharmacology
V1A V1AR Human Vasopressin and oxytocin A pKd 6.9 6.9 6.9 Guide to Pharmacology
V1B V1BR Human Vasopressin and oxytocin A pKi 5.7 6.35 7.0 Guide to Pharmacology
V1B V1BR Human Vasopressin and oxytocin A pKd 5.8 5.8 5.8 Guide to Pharmacology
V2 V2R Human Vasopressin and oxytocin A pKi 5.4 6.1 6.8 Guide to Pharmacology
V2 V2R Human Vasopressin and oxytocin A pKd 5.8 5.8 5.8 Guide to Pharmacology
OT OXYR Human Vasopressin and oxytocin A pKi 8.2 8.9 9.6 Guide to Pharmacology
OT OXYR Human Vasopressin and oxytocin A pKd 8.2 8.85 9.5 Guide to Pharmacology
V1A V1AR Rat Vasopressin and oxytocin A pKi 6.1 6.1 6.1 Guide to Pharmacology
OT OXYR Rat Vasopressin and oxytocin A pKi 8.7 8.7 8.7 Guide to Pharmacology
OT OXYR Rat Vasopressin and oxytocin A pKi 8.77 8.91 9.05 ChEMBL
V1B V1BR Human Vasopressin and oxytocin A pKi 5.75 5.75 5.75 ChEMBL
V2 V2R Human Vasopressin and oxytocin A pKi 5.46 5.63 5.81 ChEMBL
OT OXYR Human Vasopressin and oxytocin A pKd 8.17 8.17 8.17 ChEMBL
OT OXYR Human Vasopressin and oxytocin A pKi 8.02 8.85 9.36 ChEMBL
V1A V1AR Human Vasopressin and oxytocin A pKi 6.92 7.25 7.7 ChEMBL
V1B V1BR Rat Vasopressin and oxytocin A pKi 7.4 7.4 7.4 PDSP Ki database
V1A V1AR Rat Vasopressin and oxytocin A pKi 7.23 7.29 7.34 PDSP Ki database
V2 V2R Rat Vasopressin and oxytocin A pKi 6.0 6.08 6.17 PDSP Ki database
OT OXYR Rat Vasopressin and oxytocin A pKi 8.72 8.89 9.05 PDSP Ki database
V1A V1AR Human Vasopressin and oxytocin A pKi 6.91 6.91 6.91 PDSP Ki database
V2 V2R Human Vasopressin and oxytocin A pKi 5.81 5.81 5.81 PDSP Ki database
OT OXYR Human Vasopressin and oxytocin A pKi 9.15 9.23 9.3 PDSP Ki database
OT OXYR Human Vasopressin and oxytocin A pKi 8.04 8.04 8.04 Drug Central
V1A V1AR Rat Vasopressin and oxytocin A pKi 8.21 8.21 8.21 Drug Central
V2 V2R Rat Vasopressin and oxytocin A pKi 8.14 8.14 8.14 Drug Central
OT OXYR Rat Vasopressin and oxytocin A pKi 8.04 8.04 8.04 Drug Central
V1B V1BR Human Vasopressin and oxytocin A pKi 5.75 5.75 5.75 PDSP Ki database
V2 V2R Rat Vasopressin and oxytocin A pKi 7.06 7.13 7.21 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
OT OXYR Mouse Vasopressin and oxytocin A pEC50 8.7 8.7 8.7 ChEMBL
V1B V1BR Human Vasopressin and oxytocin A pEC50 6.62 8.0 9.7 ChEMBL
V2 V2R Human Vasopressin and oxytocin A pEC50 6.09 7.11 8.14 ChEMBL
OT OXYR Human Vasopressin and oxytocin A pIC50 8.57 8.57 8.57 ChEMBL
OT OXYR Human Vasopressin and oxytocin A pEC50 7.58 8.85 11.0 ChEMBL
V1A V1AR Human Vasopressin and oxytocin A pEC50 6.58 8.28 9.74 ChEMBL
V1A V1AR Human Vasopressin and oxytocin A pEC50 8.16 8.16 8.16 Drug Central
V1B V1BR Human Vasopressin and oxytocin A pEC50 8.2 8.2 8.2 Drug Central
V2 V2R Human Vasopressin and oxytocin A pEC50 8.21 8.21 8.21 Drug Central