TRH (Human) [8390]



TRH (Human)


SMILES NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1c[nH]cn1)NC(=O)[C@@H]1CCC(=O)N1
InChIKey XNSAINXGIQZQOO-SRVKXCTJSA-N
Sequence XHP
HELM PEPTIDE1{[Glp].H.P.[am]}$$$$

Chemical Properties

Hydrogen bond acceptors 5
Hydrogen bond donors 4
Rotatable bonds 6
Log P -1.808
Molecular weight (Da) 362.2
Stereochemistry info unspecified

Database connections

Structure pdb 7WKD 7XW9 7X1U
Model (Boltz2) TRH1

Bioactivities

Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database
Receptor Activity Source
Protein Gene Species Family Class Type Min Avg Max Database

TRH (Human)


Drug properties

Molecular type Peptide
Physiological/Surrogate Endogenous
Approved drug Yes

Distribution across phases (no. indications)

Phase I 0
Phase II 1
Phase III 1
Phase IV 1

Database connections

Structure pdb 7WKD 7XW9 7X1U
Model (Boltz2) TRH1

Sankey plot