ArrestinDb

Ligand source activities (1 row/activity)

Potency
Affinity

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Ligands (move mouse cursor over ligand name to see structure)					Receptor			Assay information							Chemical information
Sel. page	Common name	GPCRdb ID	#Vendors	Reference ligand	Fold selectivity	# Tested GPCRs	Species	p-value (-log)	Activity Type	Activity Relation	Activity Value	AssayType	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI
	71460332	80933	4	None	-181	3	Human	5.7	pIC50	=	5.7	Functional	Antagonist activity at human GPR99 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-induced increase in intracellular calcium level at by FLIPR assayAntagonist activity at human GPR99 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-induced increase in intracellular calcium level at by FLIPR assay	ChEMBL	429	7	1	3	6.2	C[C@H](NC(=O)CCCc1ccc2cccnc2n1)c1ccc(-c2cccc(Cl)c2)cc1	10.1016/j.bmcl.2011.04.091
	CHEMBL2153446	80933	4	None	-181	3	Human	5.7	pIC50	=	5.7	Functional	Antagonist activity at human GPR99 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-induced increase in intracellular calcium level at by FLIPR assayAntagonist activity at human GPR99 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-induced increase in intracellular calcium level at by FLIPR assay	ChEMBL	429	7	1	3	6.2	C[C@H](NC(=O)CCCc1ccc2cccnc2n1)c1ccc(-c2cccc(Cl)c2)cc1	10.1016/j.bmcl.2011.04.091
	71456641	80960	0	None	-125	3	Human	5.3	pIC50	=	5.3	Functional	Antagonist activity at human GPR99 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-induced increase in intracellular calcium level at by FLIPR assayAntagonist activity at human GPR99 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-induced increase in intracellular calcium level at by FLIPR assay	ChEMBL	426	6	0	5	6.2	Clc1cccc(-c2ccc(-c3nnc(CCCc4ccc5cccnc5n4)o3)cc2)c1	10.1016/j.bmcl.2011.04.091
	CHEMBL2153586	80960	0	None	-125	3	Human	5.3	pIC50	=	5.3	Functional	Antagonist activity at human GPR99 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-induced increase in intracellular calcium level at by FLIPR assayAntagonist activity at human GPR99 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-induced increase in intracellular calcium level at by FLIPR assay	ChEMBL	426	6	0	5	6.2	Clc1cccc(-c2ccc(-c3nnc(CCCc4ccc5cccnc5n4)o3)cc2)c1	10.1016/j.bmcl.2011.04.091
	71462027	80927	0	None	-173	3	Human	5.2	pIC50	=	5.2	Functional	Antagonist activity at human GPR99 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-induced increase in intracellular calcium level at by FLIPR assayAntagonist activity at human GPR99 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-induced increase in intracellular calcium level at by FLIPR assay	ChEMBL	415	7	1	3	5.6	O=C(CCCc1ccc2cccnc2n1)NCc1ccc(-c2cccc(Cl)c2)cc1	10.1016/j.bmcl.2011.04.091
	CHEMBL2153440	80927	0	None	-173	3	Human	5.2	pIC50	=	5.2	Functional	Antagonist activity at human GPR99 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-induced increase in intracellular calcium level at by FLIPR assayAntagonist activity at human GPR99 receptor expressed in CHO-K1 cells co-expressing Galpha and Gqi5 G-protein assessed as inhibition of succinate-induced increase in intracellular calcium level at by FLIPR assay	ChEMBL	415	7	1	3	5.6	O=C(CCCc1ccc2cccnc2n1)NCc1ccc(-c2cccc(Cl)c2)cc1	10.1016/j.bmcl.2011.04.091
	3636	361	125	None	-22908	2	Human	3.9	pEC50	=	3.9	Functional	UnclassifiedUnclassified	Guide to Pharmacology	146	4	2	3	-0.5	OC(=O)CCC(=O)C(=O)O	15141213
	3636	361	125	None	-22908	2	Human	3.9	pEC50	=	3.9	Functional	UnclassifiedUnclassified	Guide to Pharmacology	146	4	2	3	-0.5	OC(=O)CCC(=O)C(=O)O	23396314
	51	361	125	None	-22908	2	Human	3.9	pEC50	=	3.9	Functional	UnclassifiedUnclassified	Guide to Pharmacology	146	4	2	3	-0.5	OC(=O)CCC(=O)C(=O)O	15141213
	51	361	125	None	-22908	2	Human	3.9	pEC50	=	3.9	Functional	UnclassifiedUnclassified	Guide to Pharmacology	146	4	2	3	-0.5	OC(=O)CCC(=O)C(=O)O	23396314
	CHEMBL1686	361	125	None	-22908	2	Human	3.9	pEC50	=	3.9	Functional	UnclassifiedUnclassified	Guide to Pharmacology	146	4	2	3	-0.5	OC(=O)CCC(=O)C(=O)O	15141213
	CHEMBL1686	361	125	None	-22908	2	Human	3.9	pEC50	=	3.9	Functional	UnclassifiedUnclassified	Guide to Pharmacology	146	4	2	3	-0.5	OC(=O)CCC(=O)C(=O)O	23396314
	DB08845	361	125	None	-22908	2	Human	3.9	pEC50	=	3.9	Functional	UnclassifiedUnclassified	Guide to Pharmacology	146	4	2	3	-0.5	OC(=O)CCC(=O)C(=O)O	15141213
	DB08845	361	125	None	-22908	2	Human	3.9	pEC50	=	3.9	Functional	UnclassifiedUnclassified	Guide to Pharmacology	146	4	2	3	-0.5	OC(=O)CCC(=O)C(=O)O	23396314

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Ligands (move mouse cursor over ligand name to see structure)					Receptor			Assay information							Chemical information
Sel. page	Similar- ity	Common name	GPCRdb ID	#Vendors	Reference ligand	Fold selectivity	# Tested GPCRs	Species	p-value (-log)	Activity Type	Activity Relation	Activity Value	Assay Type	Assay Description	Source	Mol weight	Rot Bonds	H don	H acc	LogP	Smiles	DOI
		46875342	202176	0	None	-	1	Rat	8.0	pKi	=	8	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	449	11	5	10	-0.4	CC(=O)NCCCCCCCCNC(=O)[C@H]1OC(n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	10.1021/jm000150k
		CHEMBL609487	202176	0	None	-	1	Rat	8.0	pKi	=	8	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	449	11	5	10	-0.4	CC(=O)NCCCCCCCCNC(=O)[C@H]1OC(n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	10.1021/jm000150k
		46875317	201974	0	None	-	1	Rat	6.0	pKi	=	6.0	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	414	3	4	9	0.1	Nc1ncnc2c1ncn2C1O[C@H](C(=O)NC23CC4CC(CC(C4)C2)C3)[C@@H](O)[C@H]1O	10.1021/jm000150k
		CHEMBL608000	201974	0	None	-	1	Rat	6.0	pKi	=	6.0	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	414	3	4	9	0.1	Nc1ncnc2c1ncn2C1O[C@H](C(=O)NC23CC4CC(CC(C4)C2)C3)[C@@H](O)[C@H]1O	10.1021/jm000150k
		10089226	79290	0	None	50	4	Rat	7.9	pKi	=	7.9	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	350	6	4	9	-0.7	CCCCCNC(=O)[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	10.1021/jm000150k
		CHEMBL2113492	79290	0	None	50	4	Rat	7.9	pKi	=	7.9	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	350	6	4	9	-0.7	CCCCCNC(=O)[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	10.1021/jm000150k
		10738295	77820	0	None	-	1	Rat	7.9	pKi	=	7.9	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	376	3	4	9	-0.3	C[C@H]1CC[C@H](NC(=O)[C@H]2O[C@@H](n3cnc4c(N)ncnc43)[C@H](O)[C@@H]2O)CC1	10.1021/jm000150k
		CHEMBL2092859	77820	0	None	-	1	Rat	7.9	pKi	=	7.9	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	376	3	4	9	-0.3	C[C@H]1CC[C@H](NC(=O)[C@H]2O[C@@H](n3cnc4c(N)ncnc43)[C@H](O)[C@@H]2O)CC1	10.1021/jm000150k
		46875267	202219	0	None	-	1	Rat	6.9	pKi	=	6.9	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	434	12	4	9	1.7	CCCCCCCCCCCNC(=O)[C@H]1OC(n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	10.1021/jm000150k
		CHEMBL609768	202219	0	None	-	1	Rat	6.9	pKi	=	6.9	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	434	12	4	9	1.7	CCCCCCCCCCCNC(=O)[C@H]1OC(n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	10.1021/jm000150k
		46875320	201975	0	None	-	1	Rat	6.9	pKi	=	6.9	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	430	6	4	11	-0.6	COc1ccc(CNC(=O)[C@H]2OC(n3cnc4c(N)ncnc43)[C@H](O)[C@@H]2O)cc1OC	10.1021/jm000150k
		CHEMBL608003	201975	0	None	-	1	Rat	6.9	pKi	=	6.9	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	430	6	4	11	-0.6	COc1ccc(CNC(=O)[C@H]2OC(n3cnc4c(N)ncnc43)[C@H](O)[C@@H]2O)cc1OC	10.1021/jm000150k
		46875266	202175	0	None	-	1	Rat	6.8	pKi	=	6.8	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	448	13	4	9	2.1	CCCCCCCCCCCCNC(=O)[C@H]1OC(n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	10.1021/jm000150k
		CHEMBL609485	202175	0	None	-	1	Rat	6.8	pKi	=	6.8	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	448	13	4	9	2.1	CCCCCCCCCCCCNC(=O)[C@H]1OC(n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	10.1021/jm000150k
		9996282	19489	0	None	-3	4	Rat	6.8	pKi	=	6.8	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	323	4	5	10	-2.9	NCCNC(=O)[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	10.1021/jm000150k
		CHEMBL129903	19489	0	None	-3	4	Rat	6.8	pKi	=	6.8	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	323	4	5	10	-2.9	NCCNC(=O)[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	10.1021/jm000150k
		49797674	202147	0	None	-	1	Rat	7.8	pKi	=	7.8	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	336	5	4	9	-1.1	CCCCNC(=O)[C@H]1OC(n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	10.1021/jm000150k
		CHEMBL609186	202147	0	None	-	1	Rat	7.8	pKi	=	7.8	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	336	5	4	9	-1.1	CCCCNC(=O)[C@H]1OC(n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	10.1021/jm000150k
		10316575	79287	0	None	141	4	Rat	7.8	pKi	=	7.8	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	362	3	4	9	-0.5	Nc1ncnc2c1ncn2[C@@H]1O[C@H](C(=O)NC2CCCCC2)[C@@H](O)[C@H]1O	10.1021/jm000150k
		CHEMBL2113489	79287	0	None	141	4	Rat	7.8	pKi	=	7.8	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	362	3	4	9	-0.5	Nc1ncnc2c1ncn2[C@@H]1O[C@H](C(=O)NC2CCCCC2)[C@@H](O)[C@H]1O	10.1021/jm000150k
		21152082	201938	0	None	-	1	Rat	7.7	pKi	=	7.7	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	364	7	4	9	-0.3	CCCCCCNC(=O)[C@H]1OC(n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	10.1021/jm000150k
		CHEMBL607719	201938	0	None	-	1	Rat	7.7	pKi	=	7.7	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	364	7	4	9	-0.3	CCCCCCNC(=O)[C@H]1OC(n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	10.1021/jm000150k
		46875402	202104	0	None	-	1	Rat	6.7	pKi	=	6.7	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	336	4	4	9	-1.1	CCC(C)NC(=O)[C@H]1OC(n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	10.1021/jm000150k
		CHEMBL608895	202104	0	None	-	1	Rat	6.7	pKi	=	6.7	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	336	4	4	9	-1.1	CCC(C)NC(=O)[C@H]1OC(n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	10.1021/jm000150k
		56668023	63262	0	None	44	3	Rat	7.7	pKi	=	7.7	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	291	2	4	9	-2.0	C#CC(O)[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	10.1021/jm000150k
		CHEMBL1791423	63262	0	None	44	3	Rat	7.7	pKi	=	7.7	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	291	2	4	9	-2.0	C#CC(O)[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	10.1021/jm000150k
		46875323	202014	0	None	-	1	Rat	7.7	pKi	=	7.7	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	352	5	4	10	-1.3	CC(C)CONC(=O)[C@H]1OC(n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	10.1021/jm000150k
		CHEMBL608293	202014	0	None	-	1	Rat	7.7	pKi	=	7.7	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	352	5	4	10	-1.3	CC(C)CONC(=O)[C@H]1OC(n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	10.1021/jm000150k
		46875257	202102	0	None	-	1	Rat	7.7	pKi	=	7.7	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	378	8	4	9	0.1	CCCCCCCNC(=O)[C@H]1OC(n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	10.1021/jm000150k
		CHEMBL608888	202102	0	None	-	1	Rat	7.7	pKi	=	7.7	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	378	8	4	9	0.1	CCCCCCCNC(=O)[C@H]1OC(n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	10.1021/jm000150k
		46875347	202222	0	None	-	1	Rat	5.7	pKi	=	5.7	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	414	3	4	9	-0.0	Nc1ncnc2c1ncn2C1O[C@H](C(=O)NC2C3CC4CC(C3)CC2C4)[C@@H](O)[C@H]1O	10.1021/jm000150k
		CHEMBL609774	202222	0	None	-	1	Rat	5.7	pKi	=	5.7	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	414	3	4	9	-0.0	Nc1ncnc2c1ncn2C1O[C@H](C(=O)NC2C3CC4CC(C3)CC2C4)[C@@H](O)[C@H]1O	10.1021/jm000150k
		46875326	202015	0	None	-	1	Rat	7.7	pKi	=	7.7	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	392	9	4	9	0.5	CCCCCCCCNC(=O)[C@H]1OC(n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	10.1021/jm000150k
		CHEMBL608296	202015	0	None	-	1	Rat	7.7	pKi	=	7.7	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	392	9	4	9	0.5	CCCCCCCCNC(=O)[C@H]1OC(n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	10.1021/jm000150k
		46875346	202221	0	None	-	1	Rat	7.7	pKi	=	7.7	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	376	3	4	9	-0.1	Nc1ncnc2c1ncn2C1O[C@H](C(=O)NC2CCCCCC2)[C@@H](O)[C@H]1O	10.1021/jm000150k
		CHEMBL609773	202221	0	None	-	1	Rat	7.7	pKi	=	7.7	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	376	3	4	9	-0.1	Nc1ncnc2c1ncn2C1O[C@H](C(=O)NC2CCCCCC2)[C@@H](O)[C@H]1O	10.1021/jm000150k
		46875336	202103	0	None	-	1	Rat	7.6	pKi	=	7.6	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	390	3	4	9	0.3	Nc1ncnc2c1ncn2C1O[C@H](C(=O)NC2CCCCCCC2)[C@@H](O)[C@H]1O	10.1021/jm000150k
		CHEMBL608893	202103	0	None	-	1	Rat	7.6	pKi	=	7.6	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	390	3	4	9	0.3	Nc1ncnc2c1ncn2C1O[C@H](C(=O)NC2CCCCCCC2)[C@@H](O)[C@H]1O	10.1021/jm000150k
		377	2758	53	None	-70	15	Rat	7.6	pKi	=	7.6	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	308	3	4	9	-1.8	CCNC(=O)[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2N	10.1021/jm000150k
		425	2758	53	None	-70	15	Rat	7.6	pKi	=	7.6	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	308	3	4	9	-1.8	CCNC(=O)[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2N	10.1021/jm000150k
		448222	2758	53	None	-70	15	Rat	7.6	pKi	=	7.6	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	308	3	4	9	-1.8	CCNC(=O)[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2N	10.1021/jm000150k
		CHEMBL464859	2758	53	None	-70	15	Rat	7.6	pKi	=	7.6	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	308	3	4	9	-1.8	CCNC(=O)[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2N	10.1021/jm000150k
		46875307	202615	0	None	-	1	Rat	7.6	pKi	=	7.6	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	420	11	4	9	1.3	CCCCCCCCCCNC(=O)[C@H]1OC(n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	10.1021/jm000150k
		CHEMBL612154	202615	0	None	-	1	Rat	7.6	pKi	=	7.6	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	420	11	4	9	1.3	CCCCCCCCCCNC(=O)[C@H]1OC(n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	10.1021/jm000150k
		46875349	202224	0	None	-	1	Rat	7.5	pKi	=	7.5	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	407	10	5	10	-0.6	NCCCCCCCCNC(=O)[C@H]1OC(n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	10.1021/jm000150k
		CHEMBL609776	202224	0	None	-	1	Rat	7.5	pKi	=	7.5	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	407	10	5	10	-0.6	NCCCCCCCCNC(=O)[C@H]1OC(n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	10.1021/jm000150k
		3044933	16483	6	None	-2	6	Rat	7.5	pKi	=	7.5	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	322	4	4	9	-1.4	CCCNC(=O)[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	10.1021/jm000150k
		CHEMBL1235128	16483	6	None	-2	6	Rat	7.5	pKi	=	7.5	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	322	4	4	9	-1.4	CCCNC(=O)[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	10.1021/jm000150k
		46875268	202220	0	None	-	1	Rat	7.5	pKi	=	7.5	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	406	10	4	9	0.9	CCCCCCCCCNC(=O)[C@H]1OC(n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	10.1021/jm000150k
		CHEMBL609769	202220	0	None	-	1	Rat	7.5	pKi	=	7.5	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	406	10	4	9	0.9	CCCCCCCCCNC(=O)[C@H]1OC(n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	10.1021/jm000150k
		377	2758	53	None	-70	15	Rat	7.4	pKi	=	7.4	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	308	3	4	9	-1.8	CCNC(=O)[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2N	10.1021/jm000150k
		425	2758	53	None	-70	15	Rat	7.4	pKi	=	7.4	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	308	3	4	9	-1.8	CCNC(=O)[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2N	10.1021/jm000150k
		448222	2758	53	None	-70	15	Rat	7.4	pKi	=	7.4	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	308	3	4	9	-1.8	CCNC(=O)[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2N	10.1021/jm000150k
		CHEMBL464859	2758	53	None	-70	15	Rat	7.4	pKi	=	7.4	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	308	3	4	9	-1.8	CCNC(=O)[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2N	10.1021/jm000150k
		46875399	202051	0	None	-	1	Rat	7.4	pKi	=	7.4	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	296	2	5	10	-2.5	Nc1ncnc2c1ncn2C1O[C@H](C(=O)NO)[C@@H](O)[C@H]1O	10.1021/jm000150k
		CHEMBL608595	202051	0	None	-	1	Rat	7.4	pKi	=	7.4	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	296	2	5	10	-2.5	Nc1ncnc2c1ncn2C1O[C@H](C(=O)NO)[C@@H](O)[C@H]1O	10.1021/jm000150k
		21152084	201937	0	None	-	1	Rat	7.4	pKi	=	7.4	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	370	4	4	9	-0.7	Nc1ncnc2c1ncn2C1O[C@H](C(=O)NCc2ccccc2)[C@@H](O)[C@H]1O	10.1021/jm000150k
		CHEMBL607717	201937	0	None	-	1	Rat	7.4	pKi	=	7.4	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	370	4	4	9	-0.7	Nc1ncnc2c1ncn2C1O[C@H](C(=O)NCc2ccccc2)[C@@H](O)[C@H]1O	10.1021/jm000150k
		46875348	202223	0	None	-	1	Rat	7.3	pKi	=	7.3	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	365	5	5	10	-2.7	CC(=O)NCCNC(=O)[C@H]1OC(n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	10.1021/jm000150k
		CHEMBL609775	202223	0	None	-	1	Rat	7.3	pKi	=	7.3	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	365	5	5	10	-2.7	CC(=O)NCCNC(=O)[C@H]1OC(n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	10.1021/jm000150k
		215610	76935	4	None	-1	6	Rat	7.3	pKi	=	7.3	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	348	3	4	9	-0.9	Nc1ncnc2c1ncn2[C@@H]1O[C@H](C(=O)NC2CCCC2)[C@@H](O)[C@H]1O	10.1021/jm000150k
		CHEMBL2070508	76935	4	None	-1	6	Rat	7.3	pKi	=	7.3	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	348	3	4	9	-0.9	Nc1ncnc2c1ncn2[C@@H]1O[C@H](C(=O)NC2CCCC2)[C@@H](O)[C@H]1O	10.1021/jm000150k
		98567	191781	18	None	-4	7	Rat	7.3	pKi	=	7.3	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	294	2	4	9	-2.2	CNC(=O)[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	10.1021/jm000150k
		CHEMBL519809	191781	18	None	-4	7	Rat	7.3	pKi	=	7.3	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	294	2	4	9	-2.2	CNC(=O)[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	10.1021/jm000150k
		10738295	77810	0	None	-	1	Rat	7.3	pKi	=	7.3	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	376	3	4	9	-0.3	C[C@H]1CC[C@@H](NC(=O)[C@H]2O[C@@H](n3cnc4c(N)ncnc43)[C@H](O)[C@@H]2O)CC1	10.1021/jm000150k
		CHEMBL2092773	77810	0	None	-	1	Rat	7.3	pKi	=	7.3	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	376	3	4	9	-0.3	C[C@H]1CC[C@@H](NC(=O)[C@H]2O[C@@H](n3cnc4c(N)ncnc43)[C@H](O)[C@@H]2O)CC1	10.1021/jm000150k
		3042985	79232	2	None	1	4	Rat	7.2	pKi	=	7.2	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	310	3	4	10	-2.3	CONC(=O)[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	10.1021/jm000150k
		CHEMBL2113434	79232	2	None	1	4	Rat	7.2	pKi	=	7.2	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	310	3	4	10	-2.3	CONC(=O)[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	10.1021/jm000150k
		25244925	201622	0	None	1	3	Rat	7.2	pKi	=	7.2	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	280	2	4	9	-2.5	NC(=O)[C@H]1OC(n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	10.1021/jm000150k
		CHEMBL605866	201622	0	None	1	3	Rat	7.2	pKi	=	7.2	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	280	2	4	9	-2.5	NC(=O)[C@H]1OC(n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	10.1021/jm000150k
		46875400	202052	0	None	-	1	Rat	6.2	pKi	=	6.2	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	374	3	4	9	-0.7	Nc1ncnc2c1ncn2C1O[C@H](C(=O)NC2CC3CCC2C3)[C@@H](O)[C@H]1O	10.1021/jm000150k
		CHEMBL608596	202052	0	None	-	1	Rat	6.2	pKi	=	6.2	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	374	3	4	9	-0.7	Nc1ncnc2c1ncn2C1O[C@H](C(=O)NC2CC3CCC2C3)[C@@H](O)[C@H]1O	10.1021/jm000150k
		46875327	202048	0	None	-	1	Rat	7.2	pKi	=	7.2	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	324	4	4	10	-1.9	CCONC(=O)[C@H]1OC(n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	10.1021/jm000150k
		CHEMBL608587	202048	0	None	-	1	Rat	7.2	pKi	=	7.2	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	324	4	4	10	-1.9	CCONC(=O)[C@H]1OC(n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	10.1021/jm000150k
		10735584	79234	0	None	-5	4	Rat	5.2	pKi	=	5.2	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	336	2	4	9	-1.1	CC(C)(C)NC(=O)[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	10.1021/jm000150k
		CHEMBL2113436	79234	0	None	-5	4	Rat	5.2	pKi	=	5.2	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	336	2	4	9	-1.1	CC(C)(C)NC(=O)[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	10.1021/jm000150k
		46875331	202049	0	None	-	1	Rat	7.2	pKi	=	7.2	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	376	3	4	9	-0.3	CC1CCCCC1NC(=O)[C@H]1OC(n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	10.1021/jm000150k
		CHEMBL608591	202049	0	None	-	1	Rat	7.2	pKi	=	7.2	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	376	3	4	9	-0.3	CC1CCCCC1NC(=O)[C@H]1OC(n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O	10.1021/jm000150k
		46875260	202146	0	None	-	1	Rat	6.1	pKi	=	6.1	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	400	3	4	9	-0.3	Nc1ncnc2c1ncn2C1O[C@H](C(=O)NC23CC4CC(C2)C(C4)C3)[C@@H](O)[C@H]1O	10.1021/jm000150k
		CHEMBL609179	202146	0	None	-	1	Rat	6.1	pKi	=	6.1	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	400	3	4	9	-0.3	Nc1ncnc2c1ncn2C1O[C@H](C(=O)NC23CC4CC(C2)C(C4)C3)[C@@H](O)[C@H]1O	10.1021/jm000150k
		10449535	76934	0	None	-15	6	Rat	7.1	pKi	=	7.1	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	334	3	4	9	-1.3	Nc1ncnc2c1ncn2[C@@H]1O[C@H](C(=O)NC2CCC2)[C@@H](O)[C@H]1O	10.1021/jm000150k
		CHEMBL2070507	76934	0	None	-15	6	Rat	7.1	pKi	=	7.1	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	334	3	4	9	-1.3	Nc1ncnc2c1ncn2[C@@H]1O[C@H](C(=O)NC2CCC2)[C@@H](O)[C@H]1O	10.1021/jm000150k
		10403711	96333	33	None	-50	9	Rat	7.0	pKi	=	7.0	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	320	3	4	9	-1.7	Nc1ncnc2c1ncn2[C@@H]1O[C@H](C(=O)NC2CC2)[C@@H](O)[C@H]1O	10.1021/jm000150k
		CHEMBL261482	96333	33	None	-50	9	Rat	7.0	pKi	=	7.0	Binding	Binding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranesBinding activity of P3 purinoceptor-like protein (P3LP) using radioligand 40 nM [3H]NECA from rat brain membranes	ChEMBL	320	3	4	9	-1.7	Nc1ncnc2c1ncn2[C@@H]1O[C@H](C(=O)NC2CC2)[C@@H](O)[C@H]1O	10.1021/jm000150k
		3352	2371	28	None	15	3	Mouse	8.6	pKd	=	8.6	Binding	UnclassifiedUnclassified	Guide to Pharmacology	439	18	4	5	4.3	CCCCC/C=C\C/C=C\C=C\C=C\[C@H]([C@H](CCCC(=O)O)O)SC[C@@H](C(=O)O)N	23504326
		5280879	2371	28	None	15	3	Mouse	8.6	pKd	=	8.6	Binding	UnclassifiedUnclassified	Guide to Pharmacology	439	18	4	5	4.3	CCCCC/C=C\C/C=C\C=C\C=C\[C@H]([C@H](CCCC(=O)O)O)SC[C@@H](C(=O)O)N	23504326
		5863	2371	28	None	15	3	Mouse	8.6	pKd	=	8.6	Binding	UnclassifiedUnclassified	Guide to Pharmacology	439	18	4	5	4.3	CCCCC/C=C\C/C=C\C=C\C=C\[C@H]([C@H](CCCC(=O)O)O)SC[C@@H](C(=O)O)N	23504326
		CHEMBL509456	2371	28	None	15	3	Mouse	8.6	pKd	=	8.6	Binding	UnclassifiedUnclassified	Guide to Pharmacology	439	18	4	5	4.3	CCCCC/C=C\C/C=C\C=C\C=C\[C@H]([C@H](CCCC(=O)O)O)SC[C@@H](C(=O)O)N	23504326

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Main reference

Ligand source activities (1 row/activity)