G13 - Olfactory receptor 51V1 complex model

GPCR CLASS (FAMILY)

A (Rhodopsin)

SPECIES

Homo sapiens

G PROTEIN FAMILY

G12/13

DATE

2023-09-15

3D VIEW

NGL is a WebGL based 3D viewer powered by MMTF.


Tertiary structure confidence

(pLDDT score) avg.: 81.7

Very high (>90)
Confident (90-70)
Low (70-50)
Very low (<50)
Disordered

PTM Score: 0.5
iPTM Score: 0.3
PAE mean: 24.5


GPCR - G protein interface interactions



The biflare plot is a modified version of a flareplot, where lines are drawn between an inner concentric circle (Gα residues) and an outer concentric circle (GPCR residues) depicting the interface interactions.
Different interaction types are shown with different line types (aromatic - solid, hydrophobic - dashed, ionic - long dashed, polar - dotted, Van der Waals - dash-dot).
The interactive features include filtering on interaction type, segments, residues and backbone or sidechain interactions.


Interaction cut-off:

Residue numbering:

GPCR-G protein backbone (bb) or sidechain (sc):





Structures

Sequence Color

Gα, GPCR
Interaction cut-off: strict (stick), loose (line)

NGL is a WebGL based 3D viewer powered by MMTF.

Interaction
type		 GPCR
Segment
AA
Number		 Generic
number		 Gα
segment
AA
Number		 Generic
number
Polar TM3 R 131 3x50 G.H5 L 374 G.H5.23
Hydrophobic TM3 R 131 3x50 G.H5 L 374 G.H5.23
Van-der-waals TM3 R 131 3x50 G.H5 L 374 G.H5.23
Polar ICL2 P 138 34x50 G.H5 N 370 G.H5.19
Hydrophobic ICL2 P 138 34x50 G.H5 N 370 G.H5.19
Van-der-waals ICL2 P 138 34x50 G.H5 N 370 G.H5.19
Polar TM6 K 245 6x32 G.H5 H 368 G.H5.17
Hydrophobic TM6 K 245 6x32 G.H5 H 368 G.H5.17
Van-der-waals TM6 K 245 6x32 G.H5 H 368 G.H5.17
Hydrophobic TM3 I 135 3x54 G.H5 L 371 G.H5.20
Hydrophobic TM6 E 242 6x29 G.H5 D 364 G.H5.13
Van-der-waals TM6 E 242 6x29 G.H5 D 364 G.H5.13
Hydrophobic H8 Q 307 8x49 G.H5 L 376 G.H5.25
Van-der-waals H8 Q 307 8x49 G.H5 L 376 G.H5.25
Hydrophobic TM3 I 135 3x54 G.H5 L 374 G.H5.23
Van-der-waals TM3 I 135 3x54 G.H5 L 374 G.H5.23
Hydrophobic ICL2 L 139 34x51 G.H5 I 366 G.H5.15
Van-der-waals ICL2 L 139 34x51 G.H5 I 366 G.H5.15
Hydrophobic ICL2 L 139 34x51 G.S3 V 216 G.S3.01
Hydrophobic ICL2 L 139 34x51 G.H5 N 370 G.H5.19
Van-der-waals ICL2 L 139 34x51 G.H5 N 370 G.H5.19
Hydrophobic TM2 F 69 2x40 G.H5 Q 377 G.H5.26
Van-der-waals TM2 F 69 2x40 G.H5 Q 377 G.H5.26
Polar ICL2 L 139 34x51 G.h2s4 T 241 G.h2s4.05
Hydrophobic ICL2 L 139 34x51 G.h2s4 T 241 G.h2s4.05
Van-der-waals ICL2 L 139 34x51 G.h2s4 T 241 G.h2s4.05
Hydrophobic ICL2 L 139 34x51 G.S3 F 218 G.S3.03
Polar H8 T 305 8x47 G.H5 L 376 G.H5.25
Hydrophobic H8 T 305 8x47 G.H5 L 376 G.H5.25
Van-der-waals H8 T 305 8x47 G.H5 L 376 G.H5.25
Polar ICL2 Y 141 34x53 G.H5 Q 377 G.H5.26
Hydrophobic ICL2 Y 141 34x53 G.H5 L 374 G.H5.23
Hydrophobic ICL2 P 138 34x50 G.H5 L 367 G.H5.16
Van-der-waals ICL2 P 138 34x50 G.H5 L 367 G.H5.16
Polar ICL2 R 140 34x52 G.hns1 V 45 G.hns1.01
Hydrophobic ICL2 R 140 34x52 G.hns1 V 45 G.hns1.01
Van-der-waals ICL2 R 140 34x52 G.hns1 V 45 G.hns1.01
Hydrophobic TM6 T 249 6x36 G.H5 L 374 G.H5.23
Polar TM3 N 137 3x56 G.hns1 R 47 G.hns1.03
Hydrophobic TM3 N 137 3x56 G.hns1 R 47 G.hns1.03
Van-der-waals TM3 N 137 3x56 G.hns1 R 47 G.hns1.03
Polar ICL2 R 140 34x52 G.hns1 K 46 G.hns1.02
Hydrophobic ICL2 R 140 34x52 G.hns1 K 46 G.hns1.02
Van-der-waals ICL2 R 140 34x52 G.hns1 K 46 G.hns1.02
Hydrophobic TM3 D 130 3x49 G.H5 L 374 G.H5.23
Van-der-waals TM3 D 130 3x49 G.H5 L 374 G.H5.23
Hydrophobic TM2 Q 66 2x37 G.H5 L 376 G.H5.25
Hydrophobic ICL2 R 140 34x52 G.hns1 R 47 G.hns1.03
Van-der-waals ICL2 R 140 34x52 G.hns1 R 47 G.hns1.03
Hydrophobic ICL2 L 139 34x51 G.H5 L 367 G.H5.16
Hydrophobic TM6 K 245 6x32 G.H5 M 375 G.H5.24
Van-der-waals TM6 K 245 6x32 G.H5 M 375 G.H5.24
Polar ICL2 Y 141 34x53 G.H5 Q 373 G.H5.22
Hydrophobic ICL2 Y 141 34x53 G.H5 Q 373 G.H5.22
Van-der-waals ICL2 Y 141 34x53 G.H5 Q 373 G.H5.22
Hydrophobic TM6 L 246 6x33 G.H5 L 371 G.H5.20
Van-der-waals TM6 L 246 6x33 G.H5 L 371 G.H5.20
Polar TM2 Q 66 2x37 G.H5 Q 377 G.H5.26
Polar ICL2 R 140 34x52 G.HN Y 44 G.HN.53
Hydrophobic ICL2 R 140 34x52 G.HN Y 44 G.HN.53
Van-der-waals ICL2 R 140 34x52 G.HN Y 44 G.HN.53
Polar TM3 Y 132 3x51 G.hns1 R 47 G.hns1.03
Hydrophobic TM6 T 249 6x36 G.H5 M 375 G.H5.24
Van-der-waals TM6 T 249 6x36 G.H5 M 375 G.H5.24
Polar TM3 R 131 3x50 G.H5 Q 377 G.H5.26
Hydrophobic TM3 R 131 3x50 G.H5 Q 377 G.H5.26
Van-der-waals TM3 R 131 3x50 G.H5 Q 377 G.H5.26
Hydrophobic ICL2 L 139 34x51 G.S1 V 49 G.S1.02
Van-der-waals ICL2 L 139 34x51 G.S1 V 49 G.S1.02
Hydrophobic TM2 Q 66 2x37 G.H5 Q 373 G.H5.22
Van-der-waals TM2 Q 66 2x37 G.H5 Q 373 G.H5.22
Polar TM2 M 68 2x39 G.H5 Q 377 G.H5.26
Hydrophobic TM2 M 68 2x39 G.H5 Q 377 G.H5.26
Van-der-waals TM2 M 68 2x39 G.H5 Q 377 G.H5.26
Polar ICL2 R 140 34x52 G.S1 L 48 G.S1.01
Hydrophobic ICL2 R 140 34x52 G.S1 L 48 G.S1.01
Van-der-waals ICL2 R 140 34x52 G.S1 L 48 G.S1.01
Hydrophobic ICL2 I 144 34x56 G.hns1 K 46 G.hns1.02
Van-der-waals ICL2 I 144 34x56 G.hns1 K 46 G.hns1.02
Hydrophobic TM2 F 69 2x40 G.H5 L 376 G.H5.25
Van-der-waals TM2 F 69 2x40 G.H5 L 376 G.H5.25
Hydrophobic TM3 A 134 3x53 G.H5 L 374 G.H5.23
Van-der-waals TM3 A 134 3x53 G.H5 L 374 G.H5.23
Hydrophobic TM3 A 134 3x53 G.H5 L 371 G.H5.20