Structure information

SMO

PROTEIN CLASS

Class F (Frizzled)

PDB CODE

6D32

SPECIES

Xenopus laevis

RESOLUTION

3.750

PREFERRED CHAIN

A

REFERENCE

10.1016/J.CELL.2018.04.029

PUBLICATION DATE

May 23, 2018
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Ligand Interaction Browser

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LigandAmino AcidGeneric NumberSegmentInteraction Type
Ligand
Amino Acid
Generic Number
Segment
Interaction Type
Ligand
Amino Acid
Generic Number
Segment
Interaction Type
cyclopamine D68 N-term polar (charge-assisted hydrogen bond)
cyclopamine L81 N-term hydrophobic
cyclopamine L81 N-term Van der Waals
cyclopamine W82 N-term Van der Waals
cyclopamine W82 N-term hydrophobic
cyclopamine V130 N-term hydrophobic
cyclopamine V130 N-term Van der Waals
cyclopamine E133 N-term polar (charge-assisted hydrogen bond)
cyclopamine R134 N-term polar (charge-assisted hydrogen bond)
cyclopamine P137 N-term hydrophobic
cyclopamine P137 N-term Van der Waals
LigandAmino AcidGeneric NumberSegmentInteraction Type
Showing 1 to 11 of 11 entries

Ligands

cyclopamine

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Residue Diagrams

F T C F I T V S S F I A I Y I H M E R H 1 F Y V N A C F F V G S I G W L A 2 M V F W I V G S M M S Y Y V I I F I I V 3 T S Y F H L I T W S I P F V L T V A I L 4 L F Y G G G I L V L G I P A L V F G A R Y 5 G I F G F L A F G F V L I T F G C H F Y 6 T S M S I G T G F M A F L N I K E V L L 7
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ICL1 ECL1 ICL2 ECL2 ICL3 ECL3 N-term C-term T N K E H R E M H I Y I A I F S S V T I F C T F F T L A T F L A D R Y P A V I L F Y V N A C F F V G S I G W L A L S C V I I F I I V Y Y S M M S G V I W F V M L T Y A W H T S F K A L G T L S G K T S Y F H L I T W S I P F V L T V A I L A V N Y H Y R A G F V L A P I G L V L I G G G Y F L I R G V M T L F S I K S N H A S K I N E T M L R L G I F G F L A F G F V L I T F G C H F Y D F F N Q A E W E R S F R E Y V L C E A N V T I A E Q S L L V E K I N L F A M F G T G I S M S T W V W T K A W K R I L T I I I A W C R
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Residue Table


GPCRdb(A)
GPCRdb(F)
SMO