Structure information

C5a1 receptor

PROTEIN CLASS

Class A (Rhodopsin)

PDB CODE

7Y67

SPECIES

Homo sapiens

RESOLUTION

2.800

PREFERRED CHAIN

D

REFERENCE

10.1038/S41422-023-00779-2

PUBLICATION DATE

March 1, 2023

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Ligand Interaction Browser

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Ligand Amino Acid Generic Number Segment Interaction Type
Ligand Amino Acid Generic Number Segment Interaction Type
C089 L187 ECL2 hydrophobic
C089 C188 45.50x50 ECL2 hydrophobic
C089 E199 5.35x36 TM5 polar (charge-assisted hydrogen bond)
C089 Y258 6.51x51 TM6 Van der Waals
C089 Y258 6.51x51 TM6 polar (hydrogen bond with backbone)
C089 T261 6.54x54 TM6 polar (hydrogen bond)
C089 G262 6.55x55 TM6 Van der Waals
C089 K279 7.32x31 TM7 polar (charge-assisted hydrogen bond)
C089 D282 7.35x34 TM7 polar (charge-assisted hydrogen bond)
C089 V286 7.39x38 TM7 hydrophobic
C089 V286 7.39x38 TM7 Van der Waals

Ligands

C089

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Residue Diagrams

A N G L V G V L F V V A F I V L A L I D 1 L N L A V A D F L S C L A L P I L F T S 2 T A L L L I S A Y M N L L I L S P L I S 3 A W I A C A V A W G L A L L L T I P S 4 Y C I T L T L L P W L F G L V L R V I A V 5 V A V V A S F F I F W L P Y Q V T G I M 6 I P N I C C N I Y A F S V C L S D L K 7
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ICL1 A K R ICL1ECL1 H H W P F ECL1ICL2 P I W C Q N F R ICL2ECL2 V V R E E Y F P P K V L C G V D Y S H ECL2ICL3 R A T R S ICL3ECL3 E P S ECL3N-term M D S F N Y T T P D Y G H Y D D K D T L D L N T P V D K T S N T L N-termC-term L P S L L R N V L T E E S V V R E S K S F T R S T V D T M A Q K T Q A V C-term R V P D I L A L V I F A V V F L V G V L G N A L V V W V T A F E T I N A I W F L N L A V A D F L S C L A L P I L F T S I V Q H G G A A C S I L P S L I L L N M Y A S I L L L A T I S A D R F L L V F K G A G L A W I A C A V A W G L A L L L T I P S F L Y R D K R R E R A V A I V R L V L G F L W P L L T L T I C Y T F I L L R T W S R T K T L K V V V A V V A S F F I F W L P Y Q V T G I M M S F L S P T F L L L K K L D S L C V S F A Y I N C C I N P I I Y V V A G Q G F R K S Q G R L
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Residue Table


GPCRdb(A)
GPCRdb(A)
C5a1 receptor
ECL2
45x50 45.50x50 C188
TM5
5x36 5.35x36 E199
TM6
6x51 6.51x51 Y258
6x54 6.54x54 T261
6x55 6.55x55 G262
TM7
7x31 7.32x31 K279
7x34 7.35x34 D282
7x38 7.39x38 V286