CHEMBL253318


SMILES CN1CCc2ccc3[nH]c(=O)c4cccc5c4c3c2[C@H]1C5
InChIKey GTFWUPYRBYXCRC-CQSZACIVSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 0
Molecular weight (Da) 276.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 6.47 6.47 6.47 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.26 7.26 7.26 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 6.75 6.75 6.75 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.43 6.43 6.43 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.21 5.21 5.21 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.26 7.26 7.26 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database