CHEMBL256694


SMILES C[C@@H]1NC(NCC(F)F)=Nc2ccc(Cl)c(Cl)c21
InChIKey KNZNKJDEMHGXSO-YFKPBYRVSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 2
Molecular weight (Da) 293.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 8.74 8.74 8.74 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 6.63 6.63 6.63 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.11 8.11 8.11 ChEMBL
H1 HRH1 Human Histamine A pKi 8.59 8.59 8.59 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.92 6.92 6.92 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.12 7.12 7.12 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database