sarafotoxin S6b


SMILES None
InChIKey ZHRYDGYRZIWZPS-RAALVGGVSA-N
Sequence CSCKDMTDKECLYFCHQDVIW

Chemical properties

Hydrogen bond acceptors None
Hydrogen bond donors None
Rotatable bonds None
Molecular weight (Da)

Drug properties

Molecular type Peptide
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Structure pdb 6LRY

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
ETB EDNRB Rat Endothelin A pKi 10.89 10.91 10.92 ChEMBL
ETA EDNRA Rat Endothelin A pKi 9.62 9.84 10.06 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
ETA EDNRA Human Endothelin A pIC50 7.5 7.8 8.1 Guide to Pharmacology