CHEMBL263555


SMILES CC[C@@H](c1ccc(C(F)(F)F)cc1)N1CCN(C2(C)CCN(C(=O)c3c(C)ncnc3C)CC2)C[C@@H]1C
InChIKey BQIFXNSKBXZEIQ-CYFREDJKSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 5
Molecular weight (Da) 517.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CCR5 CCR5 Human Chemokine A pKi 8.28 8.28 8.28 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 5.04 5.04 5.04 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pKi 5.32 5.32 5.32 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 5.41 5.41 5.41 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database