CHEMBL269576


SMILES Clc1ccc(N2CCN(Cc3cnn4c3ccc3ccccc34)CC2)cc1
InChIKey LADZDZFEEAEQNW-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 3
Molecular weight (Da) 376.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D1 DRD1 Bovine Dopamine A pKi 4.35 4.35 4.35 ChEMBL
D2 DRD2 Bovine Dopamine A pKi 5.32 5.32 5.32 ChEMBL
D4 DRD4 Human Dopamine A pKi 6.85 6.85 6.85 ChEMBL
D3 DRD3 Human Dopamine A pKi 4.68 4.68 4.68 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database