CHEMBL27460


SMILES O=C1NCN(c2ccccc2)C12CCN(C1CCCc3ccccc31)CC2
InChIKey NKJVDKFKDYMREK-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 361.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.68 8.77 8.85 ChEMBL
δ OPRD Human Opioid A pKi 5.46 5.89 6.32 ChEMBL
κ OPRK Human Opioid A pKi 7.19 7.58 7.97 ChEMBL
μ OPRM Human Opioid A pKi 6.46 7.17 7.89 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pEC50 7.06 7.06 7.06 ChEMBL