RIMCAZOLE


SMILES C[C@H]1CN(CCCn2c3ccccc3c3ccccc32)C[C@@H](C)N1
InChIKey GUDVQJXODNJRIJ-CALCHBBNSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 321.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Rat 5-Hydroxytryptamine A pKi 5.0 5.0 5.0 PDSP Ki database
5-HT6 5HT6R Rat 5-Hydroxytryptamine A pKi 5.3 5.3 5.3 PDSP Ki database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 5.3 5.3 5.3 PDSP Ki database
D2 DRD2 Human Dopamine A pKi 5.06 5.06 5.06 PDSP Ki database
D3 DRD3 Human Dopamine A pKi 5.0 5.0 5.0 PDSP Ki database
H1 HRH1 Human Histamine A pKi 5.3 5.3 5.3 PDSP Ki database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
TSH TSHR Human Glycoprotein hormone A Potency 4.4 4.4 4.4 ChEMBL