tasimelteon


SMILES CCC(=O)NC[C@@H]1C[C@H]1c1cccc2c1CCO2
InChIKey PTOIAAWZLUQTIO-GXFFZTMASA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 4
Molecular weight (Da) 245.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug Yes

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
MT1 MTR1A Human Melatonin A pKi 9.5 9.5 9.5 Guide to Pharmacology
MT2 MTR1B Human Melatonin A pKi 10.2 10.2 10.2 Guide to Pharmacology
MT1 MTR1A Human Melatonin A pKi 8.02 8.02 8.02 Drug Central
MT2 MTR1B Human Melatonin A pKi 8.01 8.01 8.01 Drug Central
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database