CHEMBL3120697


SMILES O=c1oc2c(Cl)c(OCCCCN3CCC(c4noc5cc(F)ccc45)CC3)ccc2c2c1CCC2
InChIKey ZPSMXADKWDNPGI-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 510.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pKi 7.86 7.86 7.86 ChEMBL
H1 HRH1 Guinea pig Histamine A pKi 7.87 7.87 7.87 ChEMBL
D2 DRD2 Rat Dopamine A pKi 7.72 7.72 7.72 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.94 7.94 7.94 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Rat Dopamine A pIC50 8.07 8.07 8.07 ChEMBL
5-HT2C 5HT2C Rat 5-Hydroxytryptamine A pIC50 5.72 5.72 5.72 ChEMBL