CHEMBL281274


SMILES O=C1NCN(c2ccccc2)C12CCN(C1Cc3cccc4cccc1c34)CC2
InChIKey BBOAHBVXCYBKLC-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 383.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 9.2 9.24 9.28 ChEMBL
δ OPRD Human Opioid A pKi 6.6 6.6 6.6 ChEMBL
κ OPRK Human Opioid A pKi 7.58 7.59 7.6 ChEMBL
μ OPRM Human Opioid A pKi 8.2 8.21 8.23 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pEC50 7.4 7.4 7.4 ChEMBL
μ OPRM Human Opioid A pEC50 5.6 5.6 5.6 ChEMBL