CHEMBL28172


SMILES O=C1NCN(c2ccccc2)C12CCN(C1Cc3ccccc3C1)CC2
InChIKey CQRVSNCDRSTFOM-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 347.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.6 8.6 8.6 ChEMBL
δ OPRD Human Opioid A pKi 6.15 6.15 6.15 ChEMBL
κ OPRK Human Opioid A pKi 6.79 6.79 6.79 ChEMBL
μ OPRM Human Opioid A pKi 7.58 7.58 7.58 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pEC50 6.3 6.3 6.3 ChEMBL