TIQ-15


SMILES NCCCCN([C@H]1CCCc2c1nccc2)C[C@@H]1NCc2c(C1)cccc2
InChIKey MYCKNKHATQGHEV-YADHBBJMSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 7
Molecular weight (Da) 364.3

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
CXCR4 CXCR4 Human Chemokine A pIC50 5.01 7.39 8.52 ChEMBL
α2C ADA2C Human Adrenoceptors A pIC50 4.64 4.64 4.64 ChEMBL
α2A ADA2A Human Adrenoceptors A pIC50 5.43 5.43 5.43 ChEMBL
M2 ACM2 Human Acetylcholine (muscarinic) A pIC50 5.12 5.12 5.12 ChEMBL
κ OPRK Human Opioid A pIC50 5.8 5.8 5.8 ChEMBL
μ OPRM Human Opioid A pIC50 4.82 4.83 4.83 ChEMBL
D2 DRD2 Human Dopamine A pIC50 5.24 5.24 5.24 ChEMBL
CXCR4 CXCR4 Human Chemokine A pIC50 8.2 8.2 8.2 Guide to Pharmacology