CHEMBL281924


SMILES CO[C@]1(C)c2cccc3c2-c2c1ccc1c2[C@@H](C3)N(C)CC1
InChIKey JVZCJQBRRXZMQR-OXQOHEQNSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 1
Molecular weight (Da) 291.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Rat 5-Hydroxytryptamine A pKi 8.96 8.96 8.96 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.96 8.96 8.96 ChEMBL
D2 DRD2 Rat Dopamine A pKi 8.15 8.15 8.15 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 7.77 7.77 7.77 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.76 7.76 7.76 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.15 8.15 8.15 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database