CHEMBL283432


SMILES COCN1CN(c2ccccc2)C2(CCN(C3CCc4cccc(Cl)c4C3)CC2)C1=O
InChIKey ZEJXBBLSIGQZQJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 439.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.07 8.07 8.07 ChEMBL
δ OPRD Human Opioid A pKi 6.62 6.62 6.62 ChEMBL
κ OPRK Human Opioid A pKi 7.76 7.76 7.76 ChEMBL
μ OPRM Human Opioid A pKi 8.12 8.12 8.12 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database