CHEMBL283480


SMILES O=C1NCN(c2ccccc2)C12CCN(C1CCc3c(Cl)ccc(Cl)c3C1)CC2
InChIKey GKBLBGBXCLKVGY-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 429.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.25 8.25 8.25 ChEMBL
δ OPRD Human Opioid A pKi 6.17 6.17 6.17 ChEMBL
κ OPRK Human Opioid A pKi 7.36 7.36 7.36 ChEMBL
μ OPRM Human Opioid A pKi 8.14 8.14 8.14 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pEC50 5.82 5.82 5.82 ChEMBL
μ OPRM Human Opioid A pEC50 6.51 6.51 6.51 ChEMBL