CHEMBL284414


SMILES O=C1NCN(c2ccccc2)C12CCN(C1CCc3ccccc31)CC2
InChIKey FQJXOOHCZZQVHD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 347.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pKi 8.92 9.04 9.15 ChEMBL
δ OPRD Human Opioid A pKi 5.73 6.0 6.27 ChEMBL
κ OPRK Human Opioid A pKi 7.5 7.89 8.28 ChEMBL
μ OPRM Human Opioid A pKi 7.72 8.1 8.47 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
NOP OPRX Human Opioid A pEC50 5.1 5.1 5.1 ChEMBL