CHEMBL286607


SMILES COc1ccccc1N1CCN(CCN(C(=O)c2ccc(F)cc2)c2ccccn2)CC1
InChIKey YJZYDPRMWYWYCG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 434.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1A ADA1A Human Adrenoceptors A pKi 6.82 6.82 6.82 ChEMBL
5-HT1A 5HT1A Rat 5-Hydroxytryptamine A pKi 8.48 8.48 8.49 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKd 9.47 9.47 9.47 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M1 ACM1 Rat Acetylcholine (muscarinic) A Potency 4.6 4.6 4.6 ChEMBL