VER-3323


SMILES C[C@@H](CN1CCc2c1cc(Br)cc2)N
InChIKey QGRQJMXAQYGAKK-QMMMGPOBSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 254.0

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.4 6.4 6.4 Guide to Pharmacology
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.5 7.5 7.5 Guide to Pharmacology
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 8.2 8.2 8.2 Guide to Pharmacology
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.34 7.34 7.34 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.62 7.62 7.62 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.46 6.46 6.46 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
M1 ACM1 Rat Acetylcholine (muscarinic) A Potency 4.8 4.8 4.8 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pEC50 7.96 7.96 7.96 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pEC50 7.36 7.36 7.36 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pEC50 6.14 6.14 6.14 ChEMBL
NPS NPSR1 Human Neuropeptide S A Potency 4.5 4.5 4.5 ChEMBL