CHEMBL294780


SMILES c1ccc(-c2nc(CN3CCN(c4ccccc4)CC3)co2)cc1
InChIKey YJLMHUBBYHISAU-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 319.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 6.6 6.6 6.6 ChEMBL
D3 DRD3 Human Dopamine A pKi 5.4 5.4 5.4 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.52 5.64 5.76 ChEMBL
D1 DRD1 Bovine Dopamine A pKi 4.94 4.94 4.94 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database