CHEMBL301224


SMILES O=C1CC2(CCCC2)CCN1CCN1CCN(c2cc(Cl)ccc2Cl)CC1
InChIKey RBBPCEWGOONAPO-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 4
Molecular weight (Da) 409.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
α1D ADA1D Rat Adrenoceptors A pKi 9.96 9.96 9.96 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 8.1 8.1 8.1 ChEMBL
α1A ADA1A Rat Adrenoceptors A pKi 7.37 7.37 7.37 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 7.38 7.44 7.47 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 7.76 7.76 7.76 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database