CHEMBL301242


SMILES O=C(NCCCCN1CCN(c2cccc(Cl)c2Cl)CC1)c1cccc2c1-c1ccccc1C2=O
InChIKey WOWYFQWPMWYJNL-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 507.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Rat Dopamine A pKi 6.82 6.94 7.05 ChEMBL
D4 DRD4 Human Dopamine A pKi 5.73 5.8 5.95 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.31 8.52 8.85 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.05 7.3 7.71 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D2 DRD2 Human Dopamine A pIC50 7.45 7.64 7.84 ChEMBL