CHEMBL3092753


SMILES NC(N)=NC(=O)c1ccc2c(c1)Cc1ccccc1-2
InChIKey FGQLNLNSOMKVOD-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 1
Hydrogen bond donors 2
Rotatable bonds 1
Molecular weight (Da) 251.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.91 7.91 7.91 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 8.74 8.74 8.74 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 6.7 6.7 6.7 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 6.0 6.0 6.0 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.85 5.85 5.85 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pIC50 7.44 7.44 7.44 ChEMBL