CHEMBL3104091


SMILES CN1CCc2c(c3cccc4c3n2-c2ccccc2CC4)C1
InChIKey DVSMVUMYJDOPJQ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 0
Molecular weight (Da) 288.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT1E 5HT1E Human 5-Hydroxytryptamine A pKi 5.39 5.39 5.39 ChEMBL
5-HT5A 5HT5A Human 5-Hydroxytryptamine A pKi 6.12 6.12 6.13 ChEMBL
D5 DRD5 Human Dopamine A pKi 6.24 6.24 6.24 ChEMBL
5-HT1B 5HT1B Human 5-Hydroxytryptamine A pKi 5.87 5.87 5.87 ChEMBL
5-HT1D 5HT1D Human 5-Hydroxytryptamine A pKi 7.07 7.07 7.07 ChEMBL
α1B ADA1B Human Adrenoceptors A pKi 5.48 5.49 5.5 ChEMBL
α1D ADA1D Human Adrenoceptors A pKi 6.22 6.22 6.23 ChEMBL
α2B ADA2B Human Adrenoceptors A pKi 6.38 6.38 6.38 ChEMBL
M5 ACM5 Human Acetylcholine (muscarinic) A pKi 5.29 5.29 5.29 ChEMBL
α2C ADA2C Human Adrenoceptors A pKi 6.76 6.76 6.76 ChEMBL
H2 HRH2 Human Histamine A pKi 7.09 7.09 7.09 ChEMBL
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 7.0 7.0 7.0 ChEMBL
H1 HRH1 Human Histamine A pKi 7.3 7.3 7.3 ChEMBL
M3 ACM3 Human Acetylcholine (muscarinic) A pKi 5.42 5.42 5.42 ChEMBL
α1A ADA1A Human Adrenoceptors A pKi 5.62 5.62 5.62 ChEMBL
α2A ADA2A Human Adrenoceptors A pKi 6.64 6.64 6.64 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.81 6.81 6.81 ChEMBL
5-HT2B 5HT2B Human 5-Hydroxytryptamine A pKi 7.06 7.06 7.06 ChEMBL
5-HT2C 5HT2C Human 5-Hydroxytryptamine A pKi 7.98 7.99 8.0 ChEMBL
M1 ACM1 Human Acetylcholine (muscarinic) A pKi 5.35 5.38 5.4 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 7.62 7.62 7.62 ChEMBL
5-HT1A 5HT1A Human 5-Hydroxytryptamine A pKi 6.2 6.21 6.22 ChEMBL
κ OPRK Human Opioid A pKi 5.66 5.68 5.7 ChEMBL
D2 DRD2 Human Dopamine A pKi 6.08 6.08 6.08 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database