CHEMBL3287392


SMILES Clc1cccc(N2CCN(CCCCOc3ccc4ccnn4c3)CC2)c1Cl
InChIKey OUJRMAKUNWMZPB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 7
Molecular weight (Da) 418.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Human Dopamine A pKi 8.36 8.36 8.36 ChEMBL
D3 DRD3 Human Dopamine A pKi 8.64 8.64 8.64 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.38 8.53 8.68 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D3 DRD3 Human Dopamine A pEC50 7.38 7.38 7.39 ChEMBL
D2 DRD2 Human Dopamine A pEC50 5.89 5.89 5.89 ChEMBL