CHEMBL328816


SMILES Cc1cn(S(=O)(=O)c2ccc(N)cc2)c2ccccc12
InChIKey ZNRJXSHXWJKTGJ-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 2
Molecular weight (Da) 286.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKd 7.0 7.0 7.0 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 7.9 7.92 7.92 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT6 5HT6R Human 5-Hydroxytryptamine A pIC50 6.5 6.51 6.52 ChEMBL