CHEMBL3289646


SMILES Cc1ccc(N2CCN(CCCOc3ccc(F)cc3)CC2)nc1
InChIKey VFOLOUVNAQBRDB-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 4
Hydrogen bond donors 0
Rotatable bonds 6
Molecular weight (Da) 329.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
D4 DRD4 Rat Dopamine A pKi 8.96 8.96 8.96 ChEMBL
D5 DRD5 Human Dopamine A pKi 5.59 5.59 5.6 ChEMBL
D1 DRD1 Human Dopamine A pKi 6.58 6.58 6.58 ChEMBL
D3 DRD3 Human Dopamine A pKi 6.7 6.71 6.73 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.98 5.98 5.98 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database