CHEMBL3289944


SMILES Cc1cccc(S(=O)(=O)NCCCCN2CCN(c3nsc4ccccc34)CC2)c1
InChIKey GCISKOCCNUBHDG-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 444.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.8 8.8 8.8 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 7.0 7.0 7.0 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 9.4 9.4 9.4 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.06 8.06 8.06 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database