CHEMBL3289953


SMILES O=S(=O)(NCCCN1CCN(c2nsc3ccccc23)CC1)c1ccc2ccccc2c1
InChIKey XILFFKQSRRILNP-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 466.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.82 8.82 8.82 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 7.4 7.4 7.4 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.0 8.0 8.0 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.66 8.66 8.66 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database