CHEMBL3289967


SMILES Cc1cccc(S(=O)(=O)NCCCN2CCN(c3noc4ccccc34)CC2)c1
InChIKey NYRDAOIKGSCMQF-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 414.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.0 8.0 8.0 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 5.82 5.82 5.82 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 5.38 5.38 5.38 ChEMBL
D2 DRD2 Human Dopamine A pKi 5.7 5.7 5.7 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database