CHEMBL3289997


SMILES O=S(=O)(NCCCN1CCC(c2noc3cc(F)ccc23)CC1)c1ccc(OC(F)(F)F)cc1
InChIKey XRUQWQMSCMPGRN-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 8
Molecular weight (Da) 501.1

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 8.06 8.06 8.06 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 7.46 7.46 7.46 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.42 8.42 8.42 ChEMBL
D2 DRD2 Human Dopamine A pKi 7.48 7.48 7.48 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database