CHEMBL3290002


SMILES O=S(=O)(NCCCN1CCC(c2noc3cc(F)ccc23)CC1)c1cccc2ccccc12
InChIKey MUGRBHXUBJDHNE-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 7
Molecular weight (Da) 467.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 9.3 9.3 9.3 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 7.08 7.08 7.08 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.77 8.77 8.77 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.4 8.4 8.4 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database