CHEMBL3290004


SMILES O=S(=O)(NCCN1CCC(c2noc3cc(F)ccc23)CC1)c1ccc2ccccc2c1
InChIKey UBEFEBGEUSHFSH-UHFFFAOYSA-N

Chemical properties

Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Molecular weight (Da) 453.2

Drug properties

Molecular type Small molecule
Physiological/Surrogate Surrogate
Approved drug No

Database connections

Bioactivities

Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database
5-HT7 5HT7R Human 5-Hydroxytryptamine A pKi 9.4 9.4 9.4 ChEMBL
5-HT6 5HT6R Human 5-Hydroxytryptamine A pKi 6.88 6.88 6.88 ChEMBL
5-HT2A 5HT2A Human 5-Hydroxytryptamine A pKi 8.74 8.74 8.74 ChEMBL
D2 DRD2 Human Dopamine A pKi 8.28 8.28 8.28 ChEMBL
Receptor Activity Source
GTP Uniprot Species Family Class Type Min Avg Max Database